iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115797

Ensembl Protein ID

ENSSSCP00000000747.2

UniProt Accession

F1SL44; F1SL44_PIG

Genbank Protein ID

ENSSSCP00000000747

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

CU914489

Gene Name

ING4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000000701.2	ENSSSCT00000000763.2	ENSSSCP00000000747.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.00e-10	39.0	188	235

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 188  TYC-LCHQVSYGE--MIGCDNpdCSiEWFHFACVGLT---TKPRGK-WFCPRCSQ 235
           69*.*******99..********999***********...899996.******97 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

GLGTQFLFFS PGIENLPFEL QRNFQLMRDL DQRTEDLKAE IDKLATEYMS SARSLSSEEK 60
LALLKQIQEA YGKCKEFGDD KVQLAMQTYE MVDKHIRRLD TDLARFEADL KEKQIESSDY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCCTAGGAA CTCAGTTTCT TTTCTTCTCC CCAGGTATTG AAAACCTGCC CTTTGAACTG 60
CAGAGAAACT TCCAGCTCAT GAGGGACCTG GACCAAAGAA CAGAGGGTAT GTACAGAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0007050--P:cell cycle arrest
GO:0006978--P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0006260--P:DNA replication
GO:0043966--P:histone H3 acetylation
GO:0043983--P:histone H4-K12 acetylation
GO:0043981--P:histone H4-K5 acetylation
GO:0043982--P:histone H4-K8 acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0045926--P:negative regulation of growth
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001338	Ailuropoda melanoleuca	92.28	5.00e-111	392.00
IUUC-Atr-002906	Amborella trichopoda	34.58	1.00e-34	139.00
IUUC-Apl-004097	Anas platyrhynchos	93.22	3.00e-109	387.00
IUUC-Aca-004593	Anolis carolinensis	89.84	2.00e-109	387.00
IUUC-Ame-011133	Astyanax mexicanus	77.33	2.00e-105	374.00
IUUC-Bta-012699	Bos taurus	91.06	1.00e-110	392.00
IUUC-Bdi-014504	Brachypodium distachyon	35.15	5.00e-39	154.00
IUUC-Bol-015245	Brassica oleracea	31.84	8.00e-31	126.00
IUUC-Bra-017027	Brassica rapa	31.91	1.00e-30	125.00
IUUC-Cja-019988	Callithrix jacchus	92.68	1.00e-104	372.00
IUUC-Cfa-021282	Canis familiaris	92.68	1.00e-104	372.00
IUUC-Cpo-022011	Cavia porcellus	92.68	5.00e-115	406.00
IUUC-Cre-022920	Chlamydomonas reinhardtii	38.51	2.00e-29	122.00
IUUC-Csa-023203	Chlorocebus sabaeus	92.68	1.00e-104	372.00
IUUC-Cin-025479	Ciona intestinalis	59.91	5.00e-73	266.00
IUUC-Csv-026288	Ciona savignyi	53.39	7.00e-69	253.00
IUUC-Dre-028264	Danio rerio	76.52	1.00e-103	368.00
IUUC-Dno-029766	Dasypus novemcinctus	96.61	7.00e-105	372.00
IUUC-Dor-031136	Dipodomys ordii	90.95	2.00e-87	315.00
IUUC-Dme-032200	Drosophila melanogaster	87.32	2.00e-40	159.00
IUUC-Eca-033565	Equus caballus	92.68	7.00e-115	405.00
IUUC-Eeu-034948	Erinaceus europaeus	78.30	2.00e-90	324.00
IUUC-Fca-036368	Felis catus	93.09	3.00e-105	373.00
IUUC-Fal-037120	Ficedula albicollis	93.22	7.00e-109	385.00
IUUC-Gmo-038982	Gadus morhua	76.52	7.00e-104	369.00
IUUC-Gga-040771	Gallus gallus	89.84	2.00e-109	387.00
IUUC-Gac-042184	Gasterosteus aculeatus	79.32	4.00e-104	370.00
IUUC-Gma-044339	Glycine max	30.42	5.00e-33	134.00
IUUC-Ggo-045559	Gorilla gorilla	92.68	1.00e-104	372.00
IUUC-Hsa-046852	Homo sapiens	92.68	1.00e-104	372.00
IUUC-Hvu-047046	Hordeum vulgare	35.63	8.00e-37	146.00
IUUC-Itr-047978	Ictidomys tridecemlineatus	92.28	1.00e-114	404.00
IUUC-Kpa-049229	Komagataella pastoris	59.18	1.00e-16	79.30
IUUC-Lpe-050822	Leersia perrieri	34.85	3.00e-37	147.00
IUUC-Loc-052725	Lepisosteus oculatus	67.25	2.00e-77	281.00
IUUC-Laf-054057	Loxodonta africana	93.09	3.00e-105	373.00
IUUC-Mcc-055212	Macaca mulatta	86.29	7.00e-99	352.00
IUUC-Meu-056511	Macropus eugenii	91.42	1.00e-105	375.00
IUUC-Mtr-058089	Medicago truncatula	33.89	2.00e-34	139.00
IUUC-Mga-059967	Meleagris gallopavo	92.83	3.00e-109	387.00
IUUC-Mmr-060843	Microcebus murinus	91.06	4.00e-111	393.00
IUUC-Mdo-062357	Monodelphis domestica	91.87	2.00e-114	404.00
IUUC-Mmu-064093	Mus musculus	92.68	5.00e-115	406.00
IUUC-Mac-064625	Musa acuminata	35.63	6.00e-37	146.00
IUUC-Mpu-066923	Mustela putorius furo	83.97	9.00e-82	295.00
IUUC-Mlu-067754	Myotis lucifugus	85.14	2.00e-104	371.00
IUUC-Nle-069062	Nomascus leucogenys	92.68	1.00e-104	372.00
IUUC-Opr-070207	Ochotona princeps	89.83	2.00e-104	370.00
IUUC-Ont-072446	Oreochromis niloticus	76.83	1.00e-103	368.00
IUUC-Oan-073652	Ornithorhynchus anatinus	65.94	1.00e-82	298.00
IUUC-Ocu-074235	Oryctolagus cuniculus	92.68	1.00e-104	372.00
IUUC-Obr-076266	Oryza brachyantha	35.68	3.00e-37	147.00
IUUC-Ogl-077118	Oryza glaberrima	33.47	9.00e-36	143.00
IUUC-Oin-079049	Oryza indica	34.01	7.00e-36	143.00
IUUC-Ome-081291	Oryza meridionalis	33.88	4.00e-36	144.00
IUUC-Oni-082218	Oryza nivara	34.01	7.00e-36	143.00
IUUC-Opu-084171	Oryza punctata	34.29	5.00e-37	147.00
IUUC-Osa-085563	Oryza sativa	33.88	4.00e-36	144.00
IUUC-Ola-086429	Oryzias latipes	71.95	1.00e-94	338.00
IUUC-Olu-087851	Ostreococcus lucimarinus	36.60	4.00e-19	87.40
IUUC-Oga-089123	Otolemur garnettii	93.09	3.00e-105	373.00
IUUC-Oar-089524	Ovis aries	91.06	1.00e-110	392.00
IUUC-Ptr-090908	Pan troglodytes	92.28	3.00e-104	370.00
IUUC-Pan-092837	Papio anubis	91.87	2.00e-110	391.00
IUUC-Psi-093828	Pelodiscus sinensis	93.13	6.00e-107	379.00
IUUC-Ppa-096009	Physcomitrella patens	33.20	1.00e-30	126.00
IUUC-Pfo-096617	Poecilia formosa	76.83	9.00e-104	369.00
IUUC-Pab-097978	Pongo abelii	95.76	4.00e-102	363.00
IUUC-Pop-099415	Populus trichocarpa	73.68	2.00e-26	112.00
IUUC-Pca-100475	Procavia capensis	63.68	4.00e-72	263.00
IUUC-Ppe-101441	Prunus persica	33.20	3.00e-36	144.00
IUUC-Pva-102325	Pteropus vampyrus	92.68	7.00e-115	405.00
IUUC-Rno-105178	Rattus norvegicus	87.80	1.00e-120	425.00
IUUC-Sha-106773	Sarcophilus harrisii	91.87	4.00e-114	404.00
IUUC-Smo-109441	Selaginella moellendorffii	34.15	1.00e-38	152.00
IUUC-Sit-109827	Setaria italica	34.31	7.00e-36	143.00
IUUC-Sly-111750	Solanum lycopersicum	35.83	2.00e-36	145.00
IUUC-Stu-112250	Solanum tuberosum	36.25	2.00e-36	145.00
IUUC-Sbi-114826	Sorghum bicolor	34.73	3.00e-37	147.00
IUUC-Sre-115124	Sporisorium reilianum	57.53	1.00e-22	101.00
IUUC-Tgu-117270	Taeniopygia guttata	89.84	2.00e-109	387.00
IUUC-Tru-118253	Takifugu rubripes	75.40	2.00e-103	367.00
IUUC-Tni-120024	Tetraodon nigroviridis	62.45	1.00e-69	255.00
IUUC-Tca-121597	Theobroma cacao	69.84	3.00e-28	118.00
IUUC-Tae-123043	Triticum aestivum	34.54	6.00e-37	147.00
IUUC-Tbe-127558	Tupaia belangeri	92.28	5.00e-111	392.00
IUUC-Ttr-128300	Tursiops truncatus	92.73	4.00e-58	217.00
IUUC-Uma-129581	Ustilago maydis	57.63	3.00e-21	97.10
IUUC-Vvi-131487	Vitis vinifera	65.08	2.00e-26	112.00
IUUC-Xtr-132189	Xenopus tropicalis	69.00	2.00e-83	301.00
IUUC-Xma-133297	Xiphophorus maculatus	63.76	7.00e-78	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence