iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010749

Ensembl Protein ID

ENSAMXP00000011678.1

UniProt Accession

W5KVR6; W5KVR6_ASTMX

Genbank Protein ID

ENSAMXP00000011678

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01011881

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000011366.1	ENSAMXT00000011678.1	ENSAMXP00000011678.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	7.30e-15	55.3	50	120
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.00e-09	36.6	154	184

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvv.....ggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l v     + + f ahk+vLa+sS+vF+a+f+++l+e    + v i+++ p v+  l++F Yt +++ 
   Q: 50   CDVTLRVkyndlEAVDFVAHKVVLASSSPVFRAMFTNGLKECG-MEVVPIEGIHPRVMGRLIEFAYTASISV 120
           899**996665559****************************9.***********************98875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++N++gi  fA++ +c++L+++a+++i  +F
   Q: 154  PSNAIGIANFAEQIGCTELHQKAREYIYMNF 184
           89****************************9 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MYAASGMTEC KAEVTPSTSN GHRIFSYTLE SHTGAAFAIM NELRLERQLC DVTLRVKYND 60
LEAVDFVAHK VVLASSSPVF RAMFTNGLKE CGMEVVPIEG IHPRVMGRLI EFAYTASISV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTTTGAGC GACCGGCAGA CGAAAACAGA TTCCAGGGCA CAGAACTTTT AAGACCTTCA 60
GTCCTGGCGG GATCAGCTGT GTAAAGCTGT GCTGTTTTCC TGGAGAAGAT TGTCTGTACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR030563--KEAP1
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0071379--P:cellular response to prostaglandin stimulus
GO:0071466--P:cellular response to xenobiotic stimulus
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001377	Ailuropoda melanoleuca	79.08	0.00e+00	976.00
IUUC-Aca-005389	Anolis carolinensis	78.62	0.00e+00	970.00
IUUC-Bta-013505	Bos taurus	78.40	0.00e+00	968.00
IUUC-Cja-018823	Callithrix jacchus	78.23	0.00e+00	966.00
IUUC-Cfa-021202	Canis familiaris	78.74	0.00e+00	970.00
IUUC-Cpo-021830	Cavia porcellus	76.92	0.00e+00	662.00
IUUC-Csa-023728	Chlorocebus sabaeus	78.57	0.00e+00	970.00
IUUC-Cin-025195	Ciona intestinalis	54.47	0.00e+00	658.00
IUUC-Csv-026155	Ciona savignyi	52.26	2.00e-174	605.00
IUUC-Dre-027388	Danio rerio	90.80	0.00e+00	1123.00
IUUC-Dno-029066	Dasypus novemcinctus	71.97	0.00e+00	853.00
IUUC-Dor-030674	Dipodomys ordii	76.87	0.00e+00	664.00
IUUC-Dme-032165	Drosophila melanogaster	50.27	5.00e-160	558.00
IUUC-Eca-034381	Equus caballus	77.11	0.00e+00	948.00
IUUC-Eeu-034791	Erinaceus europaeus	80.15	0.00e+00	675.00
IUUC-Fca-036067	Felis catus	78.91	0.00e+00	974.00
IUUC-Gmo-039691	Gadus morhua	89.55	0.00e+00	1102.00
IUUC-Gga-040266	Gallus gallus	75.51	0.00e+00	926.00
IUUC-Gac-041866	Gasterosteus aculeatus	89.37	0.00e+00	1100.00
IUUC-Ggo-044719	Gorilla gorilla	78.74	0.00e+00	974.00
IUUC-Hsa-046255	Homo sapiens	78.74	0.00e+00	974.00
IUUC-Itr-048457	Ictidomys tridecemlineatus	78.57	0.00e+00	974.00
IUUC-Lch-049646	Latimeria chalumnae	82.28	0.00e+00	1007.00
IUUC-Loc-052022	Lepisosteus oculatus	82.63	3.00e-99	355.00
IUUC-Laf-054579	Loxodonta africana	78.57	0.00e+00	972.00
IUUC-Mcc-055315	Macaca mulatta	78.57	0.00e+00	970.00
IUUC-Meu-056288	Macropus eugenii	73.94	0.00e+00	893.00
IUUC-Mmr-061639	Microcebus murinus	78.23	0.00e+00	970.00
IUUC-Mdo-062072	Monodelphis domestica	79.59	0.00e+00	979.00
IUUC-Mmu-063622	Mus musculus	77.89	0.00e+00	966.00
IUUC-Mpu-066737	Mustela putorius furo	78.82	0.00e+00	953.00
IUUC-Mlu-068173	Myotis lucifugus	78.74	0.00e+00	971.00
IUUC-Nle-069336	Nomascus leucogenys	51.28	2.00e-151	528.00
IUUC-Opr-070432	Ochotona princeps	78.74	0.00e+00	972.00
IUUC-Ont-072160	Oreochromis niloticus	89.66	0.00e+00	1097.00
IUUC-Oan-072691	Ornithorhynchus anatinus	72.67	0.00e+00	863.00
IUUC-Ocu-073798	Oryctolagus cuniculus	78.49	0.00e+00	965.00
IUUC-Obr-076181	Oryza brachyantha	33.33	3.00e-36	147.00
IUUC-Ola-086367	Oryzias latipes	83.62	0.00e+00	1032.00
IUUC-Oga-088231	Otolemur garnettii	78.57	0.00e+00	971.00
IUUC-Oar-089227	Ovis aries	77.21	0.00e+00	946.00
IUUC-Ptr-091460	Pan troglodytes	78.74	0.00e+00	974.00
IUUC-Pan-092713	Papio anubis	78.57	0.00e+00	970.00
IUUC-Pfo-096468	Poecilia formosa	89.98	0.00e+00	1085.00
IUUC-Pab-098357	Pongo abelii	78.74	0.00e+00	974.00
IUUC-Pca-100837	Procavia capensis	78.40	0.00e+00	963.00
IUUC-Pva-103249	Pteropus vampyrus	76.19	0.00e+00	911.00
IUUC-Rno-106086	Rattus norvegicus	77.38	0.00e+00	955.00
IUUC-Sha-107245	Sarcophilus harrisii	79.42	0.00e+00	980.00
IUUC-Sar-112985	Sorex araneus	79.00	0.00e+00	971.00
IUUC-Ssc-115756	Sus scrofa	78.74	0.00e+00	974.00
IUUC-Tgu-116838	Taeniopygia guttata	55.79	3.00e-121	428.00
IUUC-Tru-117644	Takifugu rubripes	89.66	0.00e+00	1110.00
IUUC-Tni-120245	Tetraodon nigroviridis	90.17	0.00e+00	1112.00
IUUC-Tbe-127472	Tupaia belangeri	79.24	2.00e-117	416.00
IUUC-Ttr-128953	Tursiops truncatus	77.95	2.00e-148	519.00
IUUC-Vpa-130683	Vicugna pacos	76.07	0.00e+00	852.00
IUUC-Xtr-132827	Xenopus tropicalis	73.64	0.00e+00	919.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence