iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037491

Ensembl Protein ID

ENSFALP00000008528.1

UniProt Accession

U3K0H4; U3K0H4_FICAL

Genbank Protein ID

ENSFALP00000008528

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

AGTO01011210

Gene Name

ABL2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000008184.1	ENSFALT00000008566.1	ENSFALP00000008528.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.50e-12	46.9	58	115

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 58   PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 115
           67899************************.*********98..788899*********997 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MYWKLKLYQL TWGALPSAYP PQEALHRPYG CDVEPQALNE AIRWSSKENL LGATESDPNL 60
FVALYDFVAS GDNTLSITKG EKLRVLGYNQ NGEWSEVRSK NGQGWVPSNY ITPVNSLEKH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAGAGAAGAA AATGGCTGTG GACGATGGTT TGAACAGCAT ATTGGTTGCT GACAAATGAG 60
GTTGACAGTT TCGTGATTTA TTTTTAGCTG GAGAATTTTT TTTAAAACAG AAGTACTGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE

SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005623--C:cell
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0071300--P:cellular response to retinoic acid
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002263	Ailuropoda melanoleuca	88.22	0.00e+00	1821.00
IUUC-Apl-003389	Anas platyrhynchos	93.01	0.00e+00	1885.00
IUUC-Ame-010629	Astyanax mexicanus	58.81	0.00e+00	1075.00
IUUC-Bta-013370	Bos taurus	87.86	0.00e+00	1804.00
IUUC-Cja-018894	Callithrix jacchus	88.11	0.00e+00	1826.00
IUUC-Cfa-020398	Canis familiaris	97.07	0.00e+00	1226.00
IUUC-Cpo-022367	Cavia porcellus	83.85	0.00e+00	1699.00
IUUC-Csa-023386	Chlorocebus sabaeus	88.22	0.00e+00	1823.00
IUUC-Cho-024714	Choloepus hoffmanni	92.23	0.00e+00	1369.00
IUUC-Dre-027741	Danio rerio	68.95	0.00e+00	1388.00
IUUC-Dno-029246	Dasypus novemcinctus	86.52	0.00e+00	1808.00
IUUC-Dor-030416	Dipodomys ordii	81.03	0.00e+00	1627.00
IUUC-Ete-032899	Echinops telfairi	66.50	0.00e+00	718.00
IUUC-Eca-033387	Equus caballus	88.40	0.00e+00	1790.00
IUUC-Eeu-035058	Erinaceus europaeus	79.86	0.00e+00	1675.00
IUUC-Fca-036578	Felis catus	81.98	0.00e+00	1637.00
IUUC-Gmo-038509	Gadus morhua	73.63	0.00e+00	1193.00
IUUC-Gga-040638	Gallus gallus	95.39	0.00e+00	2004.00
IUUC-Gac-042550	Gasterosteus aculeatus	69.51	0.00e+00	1383.00
IUUC-Ggo-044487	Gorilla gorilla	87.86	0.00e+00	1817.00
IUUC-Hsa-046636	Homo sapiens	87.95	0.00e+00	1817.00
IUUC-Itr-048685	Ictidomys tridecemlineatus	87.77	0.00e+00	1808.00
IUUC-Lch-049530	Latimeria chalumnae	78.85	0.00e+00	1601.00
IUUC-Lpe-051291	Leersia perrieri	31.05	2.00e-22	101.00
IUUC-Loc-051933	Lepisosteus oculatus	71.72	0.00e+00	1450.00
IUUC-Laf-053802	Loxodonta africana	87.70	0.00e+00	1847.00
IUUC-Mcc-054836	Macaca mulatta	88.49	0.00e+00	1839.00
IUUC-Mga-059277	Meleagris gallopavo	96.46	0.00e+00	2013.00
IUUC-Mmr-061206	Microcebus murinus	86.55	0.00e+00	1723.00
IUUC-Mdo-062281	Monodelphis domestica	97.72	0.00e+00	1214.00
IUUC-Mmu-063847	Mus musculus	86.41	0.00e+00	1718.00
IUUC-Mac-064649	Musa acuminata	33.17	2.00e-22	100.00
IUUC-Mpu-066309	Mustela putorius furo	96.58	0.00e+00	1220.00
IUUC-Mlu-068070	Myotis lucifugus	87.77	0.00e+00	1801.00
IUUC-Nle-070062	Nomascus leucogenys	96.74	0.00e+00	1225.00
IUUC-Opr-070534	Ochotona princeps	82.21	0.00e+00	948.00
IUUC-Ont-072440	Oreochromis niloticus	66.64	0.00e+00	1358.00
IUUC-Oan-073526	Ornithorhynchus anatinus	89.44	0.00e+00	1791.00
IUUC-Ocu-074051	Oryctolagus cuniculus	86.70	0.00e+00	1720.00
IUUC-Oba-074988	Oryza barthii	30.30	1.00e-18	89.00
IUUC-Opu-083538	Oryza punctata	34.39	4.00e-23	103.00
IUUC-Oga-088767	Otolemur garnettii	82.06	0.00e+00	1620.00
IUUC-Oar-089800	Ovis aries	87.68	0.00e+00	1798.00
IUUC-Ptr-090857	Pan troglodytes	96.74	0.00e+00	1224.00
IUUC-Pan-092279	Papio anubis	87.99	0.00e+00	1816.00
IUUC-Psi-093573	Pelodiscus sinensis	92.50	0.00e+00	1898.00
IUUC-Pfo-096543	Poecilia formosa	66.23	0.00e+00	1288.00
IUUC-Pab-097949	Pongo abelii	87.54	0.00e+00	1776.00
IUUC-Pca-100370	Procavia capensis	84.62	0.00e+00	1316.00
IUUC-Pva-103220	Pteropus vampyrus	81.84	0.00e+00	1560.00
IUUC-Rno-105924	Rattus norvegicus	85.59	0.00e+00	1723.00
IUUC-Sha-107114	Sarcophilus harrisii	86.95	0.00e+00	1367.00
IUUC-Smo-109661	Selaginella moellendorffii	29.50	6.00e-23	101.00
IUUC-Sit-110219	Setaria italica	30.40	3.00e-21	97.10
IUUC-Sbi-114480	Sorghum bicolor	33.18	3.00e-24	106.00
IUUC-Ssc-115968	Sus scrofa	87.86	0.00e+00	1851.00
IUUC-Tgu-117301	Taeniopygia guttata	98.55	0.00e+00	2036.00
IUUC-Tru-118410	Takifugu rubripes	68.57	0.00e+00	1396.00
IUUC-Tni-119991	Tetraodon nigroviridis	68.50	0.00e+00	1392.00
IUUC-Tca-121389	Theobroma cacao	34.36	5.00e-24	106.00
IUUC-Tbe-127362	Tupaia belangeri	91.32	0.00e+00	1410.00
IUUC-Ttr-129291	Tursiops truncatus	87.59	0.00e+00	1811.00
IUUC-Vpa-130800	Vicugna pacos	90.69	0.00e+00	1454.00
IUUC-Xtr-132965	Xenopus tropicalis	76.37	0.00e+00	1263.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence