iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067983

Ensembl Protein ID

ENSMLUP00000004131.2

UniProt Accession

G1P2N4; G1P2N4_MYOLU

Genbank Protein ID

ENSMLUP00000004131

Protein Name

Ubiquitin-fold modifier-conjugating enzyme 1

Genbank Nucleotide ID

AAPE02047227

Gene Name

UFC1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000004543.2	ENSMLUT00000004540.2	ENSMLUP00000004131.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E2/Other	97.60	2.00e-94	342.00	IUUC-Hsa-046948

Active Site

Position(s)	Description	Evidence
116	Glycyl thioester intermediate	{ECO:0000256\|PIRSR:PIRSR008716-1}

Organism

Myotis lucifugus

Functional Description
(View)

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.

Protein Sequence
(Fasta)

MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQSLI RYVENNKNAD TDWFRLESNK 60
EGTRWFGKCW YIHDLLKYEF DIEFDIPITY PTTAPEIAVP ELDGKTAKMY RGGKICLTDH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGACG AGGCCACCCG GCGTGTCGTG TCTGAGATCC CAGTGCTGAA GACTAACGCC 60
GGACCTCGCG ATCGGGAGCT GTGGGTGCAG CGCCTCAAGG AGGAATATCA GTCTCTTATC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway

Interpro

IPR016135--UBQ-conjugating_enzyme/RWD
IPR014806--Ufc1

Pfam

PF08694--UFC1

Gene Ontology

GO:0070062--C:extracellular exosome
GO:0071568--F:UFM1 transferase activity
GO:1990592--P:protein K69-linked ufmylation
GO:0034976--P:response to endoplasmic reticulum stress

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000219	Aegilops tauschii	68.35	9.00e-31	124.00
IUUC-Aml-001773	Ailuropoda melanoleuca	96.41	5.00e-95	339.00
IUUC-Atr-002519	Amborella trichopoda	64.42	2.00e-67	247.00
IUUC-Aca-004597	Anolis carolinensis	87.35	8.00e-88	315.00
IUUC-Aly-005549	Arabidopsis lyrata	64.85	8.00e-66	242.00
IUUC-Ath-007416	Arabidopsis thaliana	64.85	8.00e-66	242.00
IUUC-Ame-011281	Astyanax mexicanus	86.23	9.00e-87	311.00
IUUC-Bta-012940	Bos taurus	98.20	2.00e-96	343.00
IUUC-Bdi-014987	Brachypodium distachyon	62.35	1.00e-61	228.00
IUUC-Bol-016532	Brassica oleracea	63.86	8.00e-66	242.00
IUUC-Bra-017971	Brassica rapa	63.86	5.00e-66	243.00
IUUC-Cel-018620	Caenorhabditis elegans	71.88	3.00e-72	263.00
IUUC-Cja-019762	Callithrix jacchus	98.19	1.00e-95	341.00
IUUC-Cfa-021172	Canis familiaris	96.41	3.00e-95	340.00
IUUC-Cpo-021575	Cavia porcellus	97.60	9.00e-96	341.00
IUUC-Cre-022894	Chlamydomonas reinhardtii	61.25	7.00e-61	226.00
IUUC-Csa-024240	Chlorocebus sabaeus	93.41	2.00e-91	327.00
IUUC-Cho-024457	Choloepus hoffmanni	96.36	1.00e-27	115.00
IUUC-Cin-025708	Ciona intestinalis	76.83	2.00e-76	277.00
IUUC-Csv-026307	Ciona savignyi	77.44	6.00e-77	279.00
IUUC-Cgl-026671	Colletotrichum gloeosporioides	25.30	1.40e-01	30.00
IUUC-Dre-027752	Danio rerio	86.75	3.00e-88	316.00
IUUC-Dno-028957	Dasypus novemcinctus	97.20	5.00e-82	295.00
IUUC-Dor-030637	Dipodomys ordii	97.01	2.00e-95	340.00
IUUC-Dme-032033	Drosophila melanogaster	79.27	2.00e-81	294.00
IUUC-Ete-033056	Echinops telfairi	94.61	2.00e-93	333.00
IUUC-Eca-034260	Equus caballus	97.60	8.00e-96	342.00
IUUC-Eeu-034785	Erinaceus europaeus	60.00	1.00e-19	88.20
IUUC-Fca-035879	Felis catus	98.19	1.00e-95	341.00
IUUC-Gmo-039023	Gadus morhua	82.21	2.00e-84	304.00
IUUC-Gga-040475	Gallus gallus	83.33	6.00e-73	265.00
IUUC-Gac-041574	Gasterosteus aculeatus	77.11	1.00e-78	284.00
IUUC-Gma-043338	Glycine max	61.82	3.00e-65	240.00
IUUC-Ggo-044713	Gorilla gorilla	96.06	2.00e-71	260.00
IUUC-Hsa-046948	Homo sapiens	97.60	8.00e-96	342.00
IUUC-Hvu-047147	Hordeum vulgare	62.73	3.00e-61	227.00
IUUC-Itr-048742	Ictidomys tridecemlineatus	97.60	8.00e-96	342.00
IUUC-Lch-049654	Latimeria chalumnae	86.75	3.00e-88	317.00
IUUC-Lpe-051422	Leersia perrieri	62.73	9.00e-62	229.00
IUUC-Loc-051920	Lepisosteus oculatus	88.55	1.00e-89	321.00
IUUC-Laf-054338	Loxodonta africana	97.60	8.00e-96	342.00
IUUC-Mcc-054927	Macaca mulatta	97.60	8.00e-96	342.00
IUUC-Meu-056831	Macropus eugenii	95.73	5.00e-93	332.00
IUUC-Mtr-058091	Medicago truncatula	62.42	8.00e-65	239.00
IUUC-Mga-059933	Meleagris gallopavo	74.75	4.00e-44	168.00
IUUC-Mmr-061433	Microcebus murinus	96.41	3.00e-95	340.00
IUUC-Mdo-061994	Monodelphis domestica	93.98	2.00e-92	330.00
IUUC-Mmu-063398	Mus musculus	95.81	6.00e-95	338.00
IUUC-Mac-064536	Musa acuminata	61.21	4.00e-63	233.00
IUUC-Mpu-066795	Mustela putorius furo	98.20	2.00e-96	343.00
IUUC-Nle-069720	Nomascus leucogenys	99.10	1.00e-62	230.00
IUUC-Opr-070723	Ochotona princeps	98.20	2.00e-96	343.00
IUUC-Ont-071509	Oreochromis niloticus	79.04	6.00e-81	292.00
IUUC-Oan-073541	Ornithorhynchus anatinus	87.23	2.00e-22	96.70
IUUC-Ocu-074044	Oryctolagus cuniculus	99.39	2.00e-95	340.00
IUUC-Oba-075612	Oryza barthii	62.35	1.00e-61	228.00
IUUC-Obr-076432	Oryza brachyantha	62.35	1.00e-61	228.00
IUUC-Ogl-077071	Oryza glaberrima	62.35	1.00e-61	228.00
IUUC-Ogu-078427	Oryza glumaepatula	62.35	1.00e-61	228.00
IUUC-Oin-079963	Oryza indica	62.35	1.00e-61	228.00
IUUC-Olo-080455	Oryza longistaminata	62.35	1.00e-61	228.00
IUUC-Oni-082562	Oryza nivara	62.35	1.00e-61	228.00
IUUC-Opu-083688	Oryza punctata	62.11	3.00e-61	227.00
IUUC-Oru-084472	Oryza rufipogon	62.35	1.00e-61	228.00
IUUC-Osa-085623	Oryza sativa	62.35	1.00e-61	228.00
IUUC-Oga-088366	Otolemur garnettii	97.60	8.00e-96	342.00
IUUC-Oar-089754	Ovis aries	97.60	7.00e-96	342.00
IUUC-Ptr-090679	Pan troglodytes	97.01	1.00e-95	341.00
IUUC-Psi-093472	Pelodiscus sinensis	90.48	8.00e-68	248.00
IUUC-Ppa-095568	Physcomitrella patens	67.28	1.00e-67	248.00
IUUC-Pfo-097314	Poecilia formosa	79.27	2.00e-79	287.00
IUUC-Pab-098562	Pongo abelii	98.20	5.00e-96	342.00
IUUC-Pop-099506	Populus trichocarpa	62.05	4.00e-65	240.00
IUUC-Pca-101030	Procavia capensis	89.16	2.00e-84	303.00
IUUC-Ppe-101757	Prunus persica	62.65	2.00e-65	241.00
IUUC-Pva-102948	Pteropus vampyrus	97.60	5.00e-96	342.00
IUUC-Rno-105014	Rattus norvegicus	95.81	9.00e-95	338.00
IUUC-Sha-107297	Sarcophilus harrisii	95.21	5.00e-94	336.00
IUUC-Sit-110317	Setaria italica	61.73	9.00e-61	225.00
IUUC-Sly-111332	Solanum lycopersicum	64.20	9.00e-65	239.00
IUUC-Stu-112719	Solanum tuberosum	64.20	9.00e-65	239.00
IUUC-Sbi-114869	Sorghum bicolor	61.73	7.00e-61	226.00
IUUC-Ssc-116009	Sus scrofa	97.60	8.00e-96	342.00
IUUC-Tru-117527	Takifugu rubripes	81.71	2.00e-81	294.00
IUUC-Tsy-119195	Tarsius syrichta	94.33	3.00e-76	276.00
IUUC-Tni-120417	Tetraodon nigroviridis	79.88	3.00e-80	290.00
IUUC-Tca-120972	Theobroma cacao	63.86	9.00e-66	242.00
IUUC-Tae-124763	Triticum aestivum	62.73	5.00e-61	226.00
IUUC-Tur-126831	Triticum urartu	62.73	3.00e-61	227.00
IUUC-Tbe-128019	Tupaia belangeri	99.29	9.00e-82	295.00
IUUC-Ttr-129013	Tursiops truncatus	98.20	2.00e-96	343.00
IUUC-Vvi-131214	Vitis vinifera	63.25	6.00e-65	239.00
IUUC-Xtr-132182	Xenopus tropicalis	87.80	5.00e-88	316.00
IUUC-Xma-133877	Xiphophorus maculatus	79.27	3.00e-79	286.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence