iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090509

UUCD1 version

UUC-PaT-00653

Ensembl Protein ID

ENSPTRP00000032441.4

UniProt Accession

H2QU92; H2QU92_PANTR

Genbank Protein ID

JAA04580.1; JAA18964.1; JAA25204.1; JAA34254.1

Protein Name

Kelch-like 7

Genbank Nucleotide ID

AC145883; GABF01003181; GABD01007896; GABE01010485

Gene Name

KLHL7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000018982.4	ENSPTRT00000035098.4	ENSPTRP00000032441.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.10e-18	67.3	44	110
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	3.70e-14	51.6	144	174

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklden 68
           +Dvil v++++++ah++vLaa+S++F+ +f++++ esk + +ve+kd +p+  ++l++F Yt +++ n
   Q: 44   CDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESK-SFEVELKDAEPDIIEQLVEFAYTARISVN 110
           9*************************************.*************************9876 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           +Nclgi  +A+++dcp+Lk  a+dfi++hF+
   Q: 144  SNCLGISVLAECLDCPELKATADDFIHQHFT 174
           8*****************************7 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MAASGVEKSS KKKTEKKLAA REEAKLLAGF MGVMNNMRKQ KTLCDVILMV QERKIPAHRV 60
VLAAASHFFN LMFTTNMLES KSFEVELKDA EPDIIEQLVE FAYTARISVN SNNVQSLLDA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAGTGCCCC CGCCTCCTTG CGCGAAGTGC GCAGGCTCCT GGGCAGGGCT TGGGTTCTGC 60
CCGGGGACGC AGCCCAGTTA GTAGCGTCGC TCCCTGAGCG CTTCTAAGGG GGCCGCCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030599--KLHL7
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001981	Ailuropoda melanoleuca	99.83	0.00e+00	1175.00
IUUC-Apl-003183	Anas platyrhynchos	98.56	0.00e+00	1160.00
IUUC-Aca-004273	Anolis carolinensis	98.20	0.00e+00	1161.00
IUUC-Ame-011343	Astyanax mexicanus	83.36	0.00e+00	969.00
IUUC-Bta-012785	Bos taurus	99.66	0.00e+00	1172.00
IUUC-Cja-019038	Callithrix jacchus	99.83	0.00e+00	1199.00
IUUC-Cfa-020774	Canis familiaris	99.82	0.00e+00	1147.00
IUUC-Cpo-021716	Cavia porcellus	99.66	0.00e+00	1169.00
IUUC-Csa-023029	Chlorocebus sabaeus	100.00	0.00e+00	1177.00
IUUC-Cho-024947	Choloepus hoffmanni	76.96	0.00e+00	849.00
IUUC-Dre-028014	Danio rerio	83.40	0.00e+00	878.00
IUUC-Dno-029946	Dasypus novemcinctus	99.66	0.00e+00	1174.00
IUUC-Dor-030916	Dipodomys ordii	83.20	6.00e-177	613.00
IUUC-Dse-031294	Dothistroma septosporum	32.95	3.00e-06	44.30
IUUC-Ete-032454	Echinops telfairi	94.01	0.00e+00	638.00
IUUC-Eca-034041	Equus caballus	99.49	0.00e+00	1173.00
IUUC-Eeu-034627	Erinaceus europaeus	98.98	0.00e+00	972.00
IUUC-Fca-035854	Felis catus	99.83	0.00e+00	1175.00
IUUC-Fal-036883	Ficedula albicollis	98.12	0.00e+00	1160.00
IUUC-Gmo-038902	Gadus morhua	78.74	0.00e+00	898.00
IUUC-Gga-040866	Gallus gallus	98.29	0.00e+00	1167.00
IUUC-Gac-041428	Gasterosteus aculeatus	78.14	0.00e+00	940.00
IUUC-Ggo-044846	Gorilla gorilla	93.86	0.00e+00	1082.00
IUUC-Hsa-047034	Homo sapiens	100.00	0.00e+00	1177.00
IUUC-Itr-048807	Ictidomys tridecemlineatus	99.62	5.00e-141	493.00
IUUC-Lch-049815	Latimeria chalumnae	89.84	0.00e+00	1055.00
IUUC-Loc-052232	Lepisosteus oculatus	84.76	0.00e+00	914.00
IUUC-Laf-053520	Loxodonta africana	99.49	0.00e+00	1171.00
IUUC-Mcc-055237	Macaca mulatta	99.83	0.00e+00	1177.00
IUUC-Meu-056095	Macropus eugenii	92.90	1.00e-175	608.00
IUUC-Mga-059927	Meleagris gallopavo	98.29	0.00e+00	1167.00
IUUC-Mvi-060550	Microbotryum violaceum	39.02	7.70e-01	29.60
IUUC-Mmr-060974	Microcebus murinus	98.57	0.00e+00	1155.00
IUUC-Mdo-062729	Monodelphis domestica	92.01	0.00e+00	1117.00
IUUC-Mmu-063841	Mus musculus	97.78	0.00e+00	1156.00
IUUC-Mpu-066524	Mustela putorius furo	97.01	0.00e+00	1165.00
IUUC-Mlu-067215	Myotis lucifugus	99.82	0.00e+00	1174.00
IUUC-Ncr-068856	Neurospora crassa	28.71	2.00e-04	39.30
IUUC-Nle-069341	Nomascus leucogenys	100.00	0.00e+00	1177.00
IUUC-Opr-070269	Ochotona princeps	99.49	0.00e+00	1172.00
IUUC-Ont-071551	Oreochromis niloticus	79.79	0.00e+00	944.00
IUUC-Oan-072718	Ornithorhynchus anatinus	99.27	0.00e+00	1150.00
IUUC-Ocu-074287	Oryctolagus cuniculus	100.00	0.00e+00	1177.00
IUUC-Ola-086718	Oryzias latipes	78.37	0.00e+00	955.00
IUUC-Oga-088757	Otolemur garnettii	99.49	0.00e+00	1174.00
IUUC-Oar-090309	Ovis aries	99.66	0.00e+00	1172.00
IUUC-Pan-092929	Papio anubis	100.00	0.00e+00	1177.00
IUUC-Psi-092941	Pelodiscus sinensis	98.74	0.00e+00	1162.00
IUUC-Pfo-097421	Poecilia formosa	79.39	0.00e+00	931.00
IUUC-Pab-097792	Pongo abelii	100.00	0.00e+00	1177.00
IUUC-Pca-101033	Procavia capensis	90.04	0.00e+00	856.00
IUUC-Pva-102364	Pteropus vampyrus	89.42	0.00e+00	1030.00
IUUC-Rno-105596	Rattus norvegicus	97.95	0.00e+00	1158.00
IUUC-Sha-106815	Sarcophilus harrisii	99.26	0.00e+00	1127.00
IUUC-Smo-109320	Selaginella moellendorffii	26.72	9.00e-16	79.00
IUUC-Sar-113305	Sorex araneus	99.15	0.00e+00	1170.00
IUUC-Ssc-115871	Sus scrofa	95.86	2.00e-168	584.00
IUUC-Tgu-116940	Taeniopygia guttata	97.78	0.00e+00	1156.00
IUUC-Tru-118682	Takifugu rubripes	78.69	0.00e+00	958.00
IUUC-Tsy-118787	Tarsius syrichta	99.21	0.00e+00	803.00
IUUC-Tni-120224	Tetraodon nigroviridis	79.26	0.00e+00	961.00
IUUC-Tbe-127633	Tupaia belangeri	57.05	6.00e-88	317.00
IUUC-Ttr-128500	Tursiops truncatus	98.39	0.00e+00	1157.00
IUUC-Vpa-130512	Vicugna pacos	97.26	0.00e+00	1118.00
IUUC-Xtr-131983	Xenopus tropicalis	96.95	0.00e+00	1146.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence