• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063302
Ensembl Protein ID ENSMUSP00000042123.5
UniProt Accession Q61792; Q62416; LASP1_MOUSE
Genbank Protein ID CAA65659.1; BAC37278.1; AAH10840.1; AAC52639.1
Protein Name LIM and SH3 domain protein 1; Metastatic lymph node gene 50 protein
Genbank Nucleotide ID X96973; AK078445; BC010840; U58882
Gene Name Lasp1; Mln50
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000038366.15 ENSMUST00000043843.11 ENSMUSP00000042123.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IIDPINAHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.70e-14 54.0 208 263
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           + ++ ydy+a+++de +++ Gd++  +  ++ d gW++g+ e +g  G++P+n+ve +
   Q: 208  RYRAVYDYSAADEDEVSFQDGDTIVNV--QQIDDGWMYGTVERTGDTGMLPANYVEAI 263
           56899*******************999..99************************975 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
 Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).
Protein Sequence
(Fasta)
MNPNCARCGK IVYPTEKVNC LDKYWHKACF HCETCKMTLN MKNYKGYEKK PYCNAHYPKQ 60
SFTMVADTPE NLRLKQQSEL QSQVRYKEEF EKNKGKGFSV VADTPELQRI KKTQDQISNI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063302|UBD,SH3|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AATCTCTTTT CAGTCTTAAG ATGCTGTCGC AGCTGCTACA CAGGTAGAAT AGGGGCAAGA 60
GAAAAGAATG GAAGAGCAAA GGCGGCCAAG CTGAAAGCAG AGGATGCCTG AATCCGAAGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063302|UBD,SH3|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0009--Actin-binding
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0406--Ion transport
KW-0440--LIM domain
KW-0479--Metal-binding
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0728--SH3 domain
KW-0813--Transport
KW-0862--Zinc
Interpro

IPR000900--Nebulin_repeat
IPR001452--SH3_domain
IPR001781--Znf_LIM
PROSITE

PS00478--LIM_DOMAIN_1
PS50023--LIM_DOMAIN_2
PS51216--NEBULIN
PS50002--SH3
Pfam

PF00412--LIM
PF00880--Nebulin
PF14604--SH3_9
PRINTS

PR00452--SH3DOMAIN
SMART

SM00132--LIM
SM00227--NEBU
SM00326--SH3
Gene Ontology

GO:0005913--C:cell-cell adherens junction
GO:0030864--C:cortical actin cytoskeleton
GO:0005737--C:cytoplasm
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0051015--F:actin filament binding
GO:0098641--F:cadherin binding involved in cell-cell adhesion
GO:0015075--F:ion transmembrane transporter activity
GO:0008270--F:zinc ion binding
GO:0006811--P:ion transport
KEGG mmu:16796
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000663 Aegilops tauschii 28.99 6.00e-04 39.30
IUUC-Aml-001609 Ailuropoda melanoleuca 91.25 1.00e-110 392.00
IUUC-Atr-002465 Amborella trichopoda 26.67 5.10e-02 32.70
IUUC-Apl-003494 Anas platyrhynchos 73.80 5.00e-96 343.00
IUUC-Aca-004462 Anolis carolinensis 85.34 1.00e-119 422.00
IUUC-Ame-011113 Astyanax mexicanus 64.26 1.00e-77 282.00
IUUC-Bta-012469 Bos taurus 93.16 4.00e-132 463.00
IUUC-Cel-018413 Caenorhabditis elegans 52.80 2.00e-36 145.00
IUUC-Cja-019344 Callithrix jacchus 87.11 2.00e-65 241.00
IUUC-Cfa-020384 Canis familiaris 94.30 1.00e-113 402.00
IUUC-Cpo-022244 Cavia porcellus 86.01 4.00e-112 397.00
IUUC-Csa-023039 Chlorocebus sabaeus 95.06 2.00e-119 421.00
IUUC-Cin-025236 Ciona intestinalis 51.39 2.00e-36 145.00
IUUC-Csv-026002 Ciona savignyi 46.01 7.00e-52 197.00
IUUC-Dre-028335 Danio rerio 66.54 6.00e-87 313.00
IUUC-Dno-029377 Dasypus novemcinctus 91.63 8.00e-101 359.00
IUUC-Dor-031101 Dipodomys ordii 97.92 2.00e-45 175.00
IUUC-Dme-031598 Drosophila melanogaster 57.03 3.00e-41 163.00
IUUC-Eca-033966 Equus caballus 92.53 1.00e-113 401.00
IUUC-Fca-035699 Felis catus 92.78 4.00e-120 423.00
IUUC-Gmo-038981 Gadus morhua 44.11 1.00e-56 212.00
IUUC-Gga-040316 Gallus gallus 82.51 7.00e-116 409.00
IUUC-Gac-042632 Gasterosteus aculeatus 61.60 1.00e-79 289.00
IUUC-Gma-042981 Glycine max 30.00 4.00e-04 39.70
IUUC-Ggo-044835 Gorilla gorilla 95.82 2.00e-116 411.00
IUUC-Hsa-046825 Homo sapiens 95.44 9.00e-122 429.00
IUUC-Hvu-047551 Hordeum vulgare 28.99 5.00e-04 39.30
IUUC-Itr-048498 Ictidomys tridecemlineatus 94.19 2.00e-116 411.00
IUUC-Lpe-050758 Leersia perrieri 35.48 1.10e-01 31.60
IUUC-Loc-052082 Lepisosteus oculatus 68.42 3.00e-90 324.00
IUUC-Laf-053578 Loxodonta africana 93.54 2.00e-117 414.00
IUUC-Mcc-055650 Macaca mulatta 95.06 2.00e-121 428.00
IUUC-Meu-056479 Macropus eugenii 90.53 4.00e-114 403.00
IUUC-Mga-059763 Meleagris gallopavo 81.97 1.00e-103 368.00
IUUC-Mmr-061164 Microcebus murinus 92.78 3.00e-117 414.00
IUUC-Mdo-061979 Monodelphis domestica 90.64 3.00e-130 457.00
IUUC-Mac-065516 Musa acuminata 33.33 8.00e-04 36.20
IUUC-Mpu-066114 Mustela putorius furo 90.49 4.00e-121 427.00
IUUC-Mlu-068217 Myotis lucifugus 94.30 1.00e-124 438.00
IUUC-Nle-069636 Nomascus leucogenys 85.23 3.00e-94 337.00
IUUC-Opr-070892 Ochotona princeps 89.73 2.00e-129 454.00
IUUC-Ont-072280 Oreochromis niloticus 62.91 1.00e-85 308.00
IUUC-Oan-073220 Ornithorhynchus anatinus 90.67 1.00e-32 130.00
IUUC-Ocu-073804 Oryctolagus cuniculus 88.59 6.00e-133 466.00
IUUC-Oba-075638 Oryza barthii 27.54 2.00e-03 37.00
IUUC-Obr-076045 Oryza brachyantha 27.94 1.00e-03 38.10
IUUC-Ogl-077659 Oryza glaberrima 27.94 2.00e-03 37.00
IUUC-Oin-079541 Oryza indica 27.94 3.00e-03 37.00
IUUC-Opu-083412 Oryza punctata 27.54 2.00e-03 38.10
IUUC-Osa-085312 Oryza sativa 27.94 2.00e-03 37.00
IUUC-Ola-086514 Oryzias latipes 63.00 2.00e-92 332.00
IUUC-Oga-088707 Otolemur garnettii 93.54 3.00e-123 434.00
IUUC-Oar-089771 Ovis aries 94.30 2.00e-134 471.00
IUUC-Ptr-091237 Pan troglodytes 95.44 9.00e-122 429.00
IUUC-Pan-092656 Papio anubis 95.06 2.00e-121 428.00
IUUC-Pma-094377 Petromyzon marinus 54.34 2.00e-65 241.00
IUUC-Pfo-097079 Poecilia formosa 57.03 5.00e-83 300.00
IUUC-Pab-097833 Pongo abelii 95.82 2.00e-116 412.00
IUUC-Pop-099698 Populus trichocarpa 29.17 5.00e-04 39.30
IUUC-Pca-100691 Procavia capensis 90.53 7.00e-116 409.00
IUUC-Pva-102270 Pteropus vampyrus 95.06 5.00e-120 423.00
IUUC-Rno-105362 Rattus norvegicus 98.48 7.00e-144 502.00
IUUC-Sce-106228 Saccharomyces cerevisiae 40.00 7.00e-07 49.30
IUUC-Sha-107134 Sarcophilus harrisii 86.56 5.00e-115 406.00
IUUC-Smo-108841 Selaginella moellendorffii 28.33 6.00e-03 35.00
IUUC-Sit-110147 Setaria italica 26.67 9.70e-02 32.00
IUUC-Sly-111106 Solanum lycopersicum 28.33 8.00e-03 35.40
IUUC-Stu-112570 Solanum tuberosum 28.33 8.00e-03 35.40
IUUC-Sre-115023 Sporisorium reilianum 55.77 4.00e-11 63.50
IUUC-Tru-118693 Takifugu rubripes 53.96 4.00e-75 274.00
IUUC-Tni-120393 Tetraodon nigroviridis 60.08 1.00e-76 278.00
IUUC-Tca-121863 Theobroma cacao 26.67 2.00e-02 34.30
IUUC-Tae-125394 Triticum aestivum 27.94 5.00e-04 39.30
IUUC-Tur-126326 Triticum urartu 28.99 6.00e-04 39.30
IUUC-Ttr-128639 Tursiops truncatus 92.02 9.00e-128 449.00
IUUC-Uma-129649 Ustilago maydis 53.85 5.00e-11 62.80
IUUC-Vpa-130114 Vicugna pacos 91.11 7.00e-68 249.00
IUUC-Vvi-131569 Vitis vinifera 24.56 4.40e-02 32.70
IUUC-Xtr-131827 Xenopus tropicalis 76.43 3.00e-110 390.00
IUUC-Xma-134054 Xiphophorus maculatus 63.98 2.00e-86 311.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved