iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033507

UUCD1 version

UUC-EqC-00074

Ensembl Protein ID

ENSECAP00000022119.1

UniProt Accession

F6QQP1; F6QQP1_HORSE

Protein Name

Uncharacterized protein

Gene Name

KLHL18

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000024577.1	ENSECAT00000026507.1	ENSECAP00000022119.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.90e-17	62.0	2	61
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.00e-09	37.6	95	125

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 7    vggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +g+ +f+ah+ivLaas ++F+a+f++++ e k ++++++++++p++++al++F Y g l +
   Q: 2    IGDHKFSAHRIVLAASIPYFHAMFTNDMMECK-QDEIVMQGMDPSALEALINFAYNGHLAI 61
           6789****************************.************************9875 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           + Nclg+++fA+++ c  L+daa++f+++hF
   Q: 95   PKNCLGVRQFAETMMCAVLYDAANSFVHQHF 125
           68***************************** PP

Organism

Equus caballus

Protein Sequence
(Fasta)

QIGDHKFSAH RIVLAASIPY FHAMFTNDMM ECKQDEIVMQ GMDPSALEAL INFAYNGHLA 60
IDQQNVQSLL MGASFLQLQS IKDACCTFLR ERLHPKNCLG VRQFAETMMC AVLYDAANSF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTTTGCCCA CAGATTGGGG ACCACAAATT CAGTGCTCAC CGGATCGTCT TAGCAGCCTC 60
AATCCCATAC TTCCACGCTA TGTTTACAAA TGACATGATG GAATGCAAAC AGGATGAGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001536	Ailuropoda melanoleuca	97.93	0.00e+00	1094.00
IUUC-Apl-003270	Anas platyrhynchos	90.40	0.00e+00	1003.00
IUUC-Aca-005395	Anolis carolinensis	91.17	0.00e+00	1028.00
IUUC-Bta-013481	Bos taurus	96.09	0.00e+00	1080.00
IUUC-Cel-018622	Caenorhabditis elegans	45.05	1.00e-135	476.00
IUUC-Cja-019847	Callithrix jacchus	98.31	0.00e+00	1093.00
IUUC-Cfa-020341	Canis familiaris	97.93	0.00e+00	1092.00
IUUC-Cpo-021613	Cavia porcellus	96.79	0.00e+00	1073.00
IUUC-Csa-023611	Chlorocebus sabaeus	97.93	0.00e+00	1091.00
IUUC-Cin-025289	Ciona intestinalis	55.20	1.00e-177	615.00
IUUC-Dre-028248	Danio rerio	84.12	0.00e+00	957.00
IUUC-Dno-029609	Dasypus novemcinctus	96.80	0.00e+00	1086.00
IUUC-Dor-030541	Dipodomys ordii	96.48	7.00e-150	523.00
IUUC-Dme-032107	Drosophila melanogaster	54.80	0.00e+00	633.00
IUUC-Eeu-034750	Erinaceus europaeus	89.27	0.00e+00	974.00
IUUC-Fca-035731	Felis catus	98.50	0.00e+00	1102.00
IUUC-Fal-036959	Ficedula albicollis	91.01	0.00e+00	1002.00
IUUC-Gga-040166	Gallus gallus	92.92	0.00e+00	1050.00
IUUC-Ggo-044853	Gorilla gorilla	97.93	0.00e+00	1091.00
IUUC-Hsa-046437	Homo sapiens	97.56	0.00e+00	1083.00
IUUC-Itr-048529	Ictidomys tridecemlineatus	97.02	0.00e+00	1066.00
IUUC-Lch-050195	Latimeria chalumnae	78.07	0.00e+00	855.00
IUUC-Loc-051787	Lepisosteus oculatus	86.79	0.00e+00	931.00
IUUC-Laf-053489	Loxodonta africana	97.56	0.00e+00	1088.00
IUUC-Mcc-055250	Macaca mulatta	97.02	0.00e+00	1085.00
IUUC-Meu-056871	Macropus eugenii	88.16	0.00e+00	981.00
IUUC-Mga-059425	Meleagris gallopavo	92.92	0.00e+00	1046.00
IUUC-Mmr-061394	Microcebus murinus	97.58	0.00e+00	1095.00
IUUC-Mdo-062285	Monodelphis domestica	95.30	0.00e+00	1071.00
IUUC-Mmu-063975	Mus musculus	97.58	0.00e+00	1095.00
IUUC-Mpu-066369	Mustela putorius furo	98.31	0.00e+00	1098.00
IUUC-Mlu-067832	Myotis lucifugus	95.84	0.00e+00	1064.00
IUUC-Nle-069338	Nomascus leucogenys	90.07	0.00e+00	973.00
IUUC-Opr-071035	Ochotona princeps	85.69	0.00e+00	929.00
IUUC-Ont-071440	Oreochromis niloticus	82.80	0.00e+00	913.00
IUUC-Ola-087275	Oryzias latipes	81.70	0.00e+00	897.00
IUUC-Oga-087921	Otolemur garnettii	98.68	0.00e+00	1102.00
IUUC-Oar-089968	Ovis aries	89.05	0.00e+00	965.00
IUUC-Ptr-091272	Pan troglodytes	97.93	0.00e+00	1091.00
IUUC-Pan-092629	Papio anubis	97.74	0.00e+00	1087.00
IUUC-Psi-093456	Pelodiscus sinensis	94.81	0.00e+00	1000.00
IUUC-Pma-094509	Petromyzon marinus	69.17	0.00e+00	746.00
IUUC-Pfo-096450	Poecilia formosa	79.02	0.00e+00	902.00
IUUC-Pab-097917	Pongo abelii	97.74	0.00e+00	1090.00
IUUC-Pca-100330	Procavia capensis	96.89	8.00e-151	526.00
IUUC-Pva-103189	Pteropus vampyrus	99.06	0.00e+00	1105.00
IUUC-Pyt-104758	Pyrenophora triticirepentis	35.71	1.00e-05	43.10
IUUC-Sha-107283	Sarcophilus harrisii	95.15	0.00e+00	1038.00
IUUC-Sar-112989	Sorex araneus	97.36	0.00e+00	1084.00
IUUC-Tgu-117146	Taeniopygia guttata	81.95	0.00e+00	860.00
IUUC-Tru-118132	Takifugu rubripes	82.14	0.00e+00	891.00
IUUC-Tni-120892	Tetraodon nigroviridis	79.21	0.00e+00	893.00
IUUC-Tbe-127347	Tupaia belangeri	95.11	0.00e+00	1058.00
IUUC-Ttr-128343	Tursiops truncatus	76.08	0.00e+00	788.00
IUUC-Vpa-130796	Vicugna pacos	84.02	0.00e+00	899.00
IUUC-Xtr-132077	Xenopus tropicalis	83.36	0.00e+00	898.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence