• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Tag Content
iUUCD ID IUUC-Mpu-065898
Ensembl Protein ID ENSMPUP00000016451.1
UniProt Accession M3YYP1; M3YYP1_MUSPF
Genbank Protein ID ENSMPUP00000016451
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEYP01085034
Gene Name SMURF1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMPUG00000016554.1 ENSMPUT00000016696.1 ENSMPUP00000016451.1
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/HECT 1.30e-127 425.9 389 724
Active Site
Position(s) Description Evidence
693 Glycyl thioester intermediate {ECO:0000256|PIRSR:PIRSR001569-1,
ECO:0000256|PROSITE-ProRule:PRU00104}
Domain Profile

   E3 activity/HECT
   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldl 90
           ++dlkkrl+v+f+gEegld+gGv+re+l+ll++e+ np++glf+ys ++ ++lq+npds + np+hl++F+f+Gr++g+a+++g++++ 
   Q: 389  PKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSSI-NPDHLSYFHFVGRIMGLAVFHGHYING 476
           689*********************************************************9.89************************* PP
   S: 91   plsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvve 179
            ++ +fyk+llgk+++l+dle+vdpel+ksl +i+en   di+   ld tf+v+++ +g + ++eLkp+G+n+pVt+eNk+eYv+l+v+
   Q: 477  GFTVPFYKQLLGKPIQLSDLESVDPELHKSLVWILEN---DITPV-LDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVN 561
           ***********************************99...9***8.******************************************* PP
   S: 180  yrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFv 268
           +r+ +gi+ q+ a+++Gfne+ip++ll+ F+++elel+i G ++idv+d+k++t+ k+ + +ds+ ++wFw+++e f++e r+++LqFv
   Q: 562  WRFMRGIEAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDVSDWKSNTRLKH-CGADSNIVRWFWQAVETFDEERRARLLQFV 649
           ********************************************************99.****************************** PP
   S: 269  TgssrlPlgGfaelk.......prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           Tgs r+Pl+Gf++l+       prlf+i+  da++d+lP+++TCfn++++P+Y+s+e+l+ekLl+A+eet gF +
   Q: 650  TGSTRVPLQGFKALQgstgaagPRLFTIHLiDANTDNLPKAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAV 724
           ******************************99999**************************************76 PP
   
Organism Mustela putorius furo
Protein Sequence
(Fasta)
MGDWFQTKVS FEILCAKNLA KKDFFRLPDP FAKIVVDGSG QCHSTDTVKN TLDPKWNQHY 60
DLYVGKTDSI TISVWNHKKI HKKQGAGFLG CVRLLSNAIS RLKDTGYQRL DLCKLNPSDT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mpu-065898|E3,HECT|Mustela putorius furo
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGTGATT GGTTTCAAAC TAAAGTTTCC TTTGAAAGTA CGTAGTTGTT GCATGATTTA 60
TTTTTTTTCA AAGAGGTTTT ATATAGATAG ATAGATAGCT ATATATATAT ATAGATAGAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mpu-065898|E3,HECT|Mustela putorius furo
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
Interpro

IPR000008--C2_dom
IPR000569--HECT_dom
IPR001202--WW_dom
PROSITE

PS50004--C2
PS50237--HECT
PS01159--WW_DOMAIN_1
PS50020--WW_DOMAIN_2
Pfam

PF00168--C2
PF00632--HECT
PF00397--WW
SMART

SM00239--C2
SM00119--HECTc
SM00456--WW
Gene Ontology

GO:0070062--C:extracellular exosome
GO:0005739--C:mitochondrion
GO:0005886--C:plasma membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0030509--P:BMP signaling pathway
GO:0061736--P:engulfment of target by autophagosome
GO:0030279--P:negative regulation of ossification
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1903861--P:positive regulation of dendrite extension
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0006611--P:protein export from nucleus
GO:0034394--P:protein localization to cell surface
GO:0000209--P:protein polyubiquitination
GO:0071211--P:protein targeting to vacuole involved in autophagy
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0032801--P:receptor catabolic process
GO:0061753--P:substrate localization to autophagosome
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001459 Ailuropoda melanoleuca 92.97 0.00e+00 1428.00
IUUC-Apl-004155 Anas platyrhynchos 93.16 0.00e+00 1433.00
IUUC-Aca-005238 Anolis carolinensis 94.59 0.00e+00 1422.00
IUUC-Ame-010901 Astyanax mexicanus 89.85 0.00e+00 1350.00
IUUC-Bta-013221 Bos taurus 91.61 0.00e+00 1359.00
IUUC-Cja-018985 Callithrix jacchus 95.03 0.00e+00 1464.00
IUUC-Cfa-020568 Canis familiaris 95.05 0.00e+00 1454.00
IUUC-Cpo-022531 Cavia porcellus 94.49 0.00e+00 1456.00
IUUC-Csa-024145 Chlorocebus sabaeus 97.77 0.00e+00 1467.00
IUUC-Cho-024963 Choloepus hoffmanni 77.47 0.00e+00 927.00
IUUC-Dre-028341 Danio rerio 90.14 0.00e+00 1361.00
IUUC-Dno-029705 Dasypus novemcinctus 94.73 0.00e+00 1431.00
IUUC-Dme-031740 Drosophila melanogaster 70.85 1.00e-174 607.00
IUUC-Eca-034125 Equus caballus 95.26 0.00e+00 1457.00
IUUC-Fca-035905 Felis catus 99.02 0.00e+00 1464.00
IUUC-Fal-037336 Ficedula albicollis 96.23 0.00e+00 1420.00
IUUC-Gmo-039486 Gadus morhua 80.30 0.00e+00 870.00
IUUC-Gga-040218 Gallus gallus 95.34 0.00e+00 1442.00
IUUC-Gac-041707 Gasterosteus aculeatus 83.61 0.00e+00 1251.00
IUUC-Ggo-045408 Gorilla gorilla 89.61 0.00e+00 1357.00
IUUC-Hsa-045878 Homo sapiens 94.89 0.00e+00 1463.00
IUUC-Itr-048317 Ictidomys tridecemlineatus 95.26 0.00e+00 1457.00
IUUC-Loc-052628 Lepisosteus oculatus 84.77 0.00e+00 1338.00
IUUC-Laf-053644 Loxodonta africana 92.73 0.00e+00 1400.00
IUUC-Mcc-055479 Macaca mulatta 89.83 0.00e+00 1316.00
IUUC-Mga-059723 Meleagris gallopavo 92.08 0.00e+00 1399.00
IUUC-Mdo-063005 Monodelphis domestica 97.21 0.00e+00 1461.00
IUUC-Mmu-063634 Mus musculus 97.49 0.00e+00 1444.00
IUUC-Mlu-067584 Myotis lucifugus 95.14 0.00e+00 1459.00
IUUC-Nle-069033 Nomascus leucogenys 95.40 0.00e+00 1460.00
IUUC-Ont-072265 Oreochromis niloticus 82.35 0.00e+00 1264.00
IUUC-Oan-073621 Ornithorhynchus anatinus 91.29 0.00e+00 1427.00
IUUC-Ocu-073960 Oryctolagus cuniculus 93.93 0.00e+00 1427.00
IUUC-Oga-088579 Otolemur garnettii 94.89 0.00e+00 1461.00
IUUC-Oar-090396 Ovis aries 93.14 0.00e+00 1363.00
IUUC-Ptr-091624 Pan troglodytes 94.89 0.00e+00 1463.00
IUUC-Pan-092479 Papio anubis 95.14 0.00e+00 1459.00
IUUC-Pfo-097203 Poecilia formosa 83.77 0.00e+00 1264.00
IUUC-Pab-097540 Pongo abelii 94.51 0.00e+00 1391.00
IUUC-Pca-100379 Procavia capensis 72.94 0.00e+00 644.00
IUUC-Rno-105396 Rattus norvegicus 97.63 0.00e+00 1447.00
IUUC-Sha-107216 Sarcophilus harrisii 94.07 0.00e+00 1446.00
IUUC-Ssc-116413 Sus scrofa 97.35 0.00e+00 1431.00
IUUC-Tgu-116723 Taeniopygia guttata 92.99 0.00e+00 1410.00
IUUC-Tru-117843 Takifugu rubripes 81.77 0.00e+00 1248.00
IUUC-Tsy-119455 Tarsius syrichta 94.62 0.00e+00 1363.00
IUUC-Tni-120829 Tetraodon nigroviridis 78.86 0.00e+00 1191.00
IUUC-Tbe-127879 Tupaia belangeri 81.72 0.00e+00 1195.00
IUUC-Ttr-128423 Tursiops truncatus 94.31 0.00e+00 1386.00
IUUC-Xtr-132237 Xenopus tropicalis 87.62 0.00e+00 1357.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved