iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-005341

UUCD1 version

UUC-AnC-00404

Ensembl Protein ID

ENSACAP00000009503.2

UniProt Accession

H9GFH7; H9GFH7_ANOCA

Protein Name

Uncharacterized protein

Gene Name

HECTD4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000009550.2	ENSACAT00000009700.2	ENSACAP00000009503.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.20e-76	258.2	3627	3987

Active Site

Position(s)	Description	Evidence
3961	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkkrlevefvgEegldlgGvtreflallskelqnpdlglf.......lysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           d ++ ++++f+gEe+++++G++r+fl++++kelq++ l+l+       ++++++k+ l+p+p s+     +++l +f+G+llg+a++
   Q: 3627 DPTYAFNIRFTGEEVHGTSGSFRHFLWQVCKELQSSLLSLLllcpssaVNKNKGKYILTPSPISY----GEEQLLHFFGQLLGIAIR 3709
           5667788********************************99999999888888***********9....789*************** PP
   S: 84   dgrlldlplsksfyklllgkklsl.edleevdpelykslkeikena.esdieelgldltfs.vseei...............lgetk 152
            + +l+l+l +sf+k+l+g+ l+   dl+e d  +y+++k+ ++++ e+++e+l+++++++     +                 + +
   Q: 3710 ADVPLPLDLLPSFWKTLVGEALDPdLDLQEADVLTYNYVKKFENLNdEAELEALCAEIASQhL-AMEspdcpnkpsckftylTMTGE 3795
           ************************88************8888877535677777777777742.22246788899999996555556 PP
   S: 153  eeeLkpgGenipVtneNkeeYvklvveyrlke.gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykgg 238
           e+eL+ +G++ipV +eNk+ Y +++ ++rl+e +  e+  a+r+G+ ++ipl+ll+++t+ e+el +cG + i++e lk++t+y+ g
   Q: 3796 EVELCARGRHIPVVWENKDVYASAIRNLRLRElQTPECAMAVRAGLGSIIPLQLLTMLTPLEMELRTCGLPFINLEFLKAHTMYQVG 3882
           667*****************************9999*************************************************** PP
   S: 239  ytedspaiqwFwevleefsseerkafLqFvTgssrlPl......gGfaelk....prlfvirk...dasddrlPssnTCfnyLkLPe 312
           ++e++++i++Fw +le+f++ee ++f++F+++++r+P+      gG ++ +    p+++  ++    + d+r+++++TC++++kLP+
   Q: 3883 LMETDQHIEFFWGALEMFTQEELCKFIKFACNQERIPFtcpckdGGPDTAHvppyPMKIAPPDgtaGSPDSRYIRVETCMFMIKLPQ 3969
           ********************************************99999999988888888889955555***************** PP
   S: 313  YsskeilkekLlyAieet 330
           Yss +i+ ekL+yAi+++
   Q: 3970 YSSLDIMLEKLRYAIHYR 3987
           ***************986 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MPADHFPVGS TMTTVHLSSD GTYFYWIWSP ASLNEKTPKG HSVFMDVFEL TMKDGVCVAN 60
PLQERIILMR KEGDSAKSIN EMLLSRLSRY RASPSATLAA LTGSTISNTL KEDQAAANTS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGCCG ACCACTTCCC CGTGGGCAGC ACCATGACCA CAGTCCACCT TTCCTCGGAT 60
GGGACCTACT TCTACTGGAT CTGGTCACCT GCGAGCTTGA ATGAGAAAAC GCCCAAGGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002256	Ailuropoda melanoleuca	90.64	0.00e+00	4954.00
IUUC-Apl-004161	Anas platyrhynchos	92.40	0.00e+00	5228.00
IUUC-Ame-011574	Astyanax mexicanus	78.58	0.00e+00	4292.00
IUUC-Bta-012514	Bos taurus	85.24	0.00e+00	1749.00
IUUC-Cja-019148	Callithrix jacchus	89.95	0.00e+00	4986.00
IUUC-Cfa-020499	Canis familiaris	89.24	0.00e+00	4952.00
IUUC-Cpo-021894	Cavia porcellus	93.81	0.00e+00	2685.00
IUUC-Csa-023079	Chlorocebus sabaeus	88.17	0.00e+00	6622.00
IUUC-Cho-024415	Choloepus hoffmanni	86.39	0.00e+00	4654.00
IUUC-Dre-027452	Danio rerio	74.44	0.00e+00	5675.00
IUUC-Dno-029595	Dasypus novemcinctus	87.23	0.00e+00	6617.00
IUUC-Dor-030849	Dipodomys ordii	90.48	0.00e+00	1571.00
IUUC-Ete-032563	Echinops telfairi	81.30	0.00e+00	1068.00
IUUC-Eca-034202	Equus caballus	90.86	0.00e+00	4950.00
IUUC-Eeu-035175	Erinaceus europaeus	92.41	0.00e+00	1035.00
IUUC-Fca-036295	Felis catus	87.28	0.00e+00	6434.00
IUUC-Fal-037003	Ficedula albicollis	89.80	0.00e+00	6040.00
IUUC-Gmo-038579	Gadus morhua	84.93	0.00e+00	2871.00
IUUC-Gga-040961	Gallus gallus	89.78	0.00e+00	6837.00
IUUC-Gac-041899	Gasterosteus aculeatus	84.72	0.00e+00	2904.00
IUUC-Ggo-045099	Gorilla gorilla	88.92	0.00e+00	5824.00
IUUC-Hsa-046331	Homo sapiens	88.27	0.00e+00	6665.00
IUUC-Itr-048190	Ictidomys tridecemlineatus	85.34	0.00e+00	1942.00
IUUC-Lch-049923	Latimeria chalumnae	81.76	0.00e+00	2506.00
IUUC-Loc-052630	Lepisosteus oculatus	83.55	0.00e+00	4018.00
IUUC-Laf-053394	Loxodonta africana	88.22	0.00e+00	6668.00
IUUC-Mcc-055763	Macaca mulatta	88.17	0.00e+00	6610.00
IUUC-Meu-056039	Macropus eugenii	85.94	0.00e+00	4935.00
IUUC-Mga-059500	Meleagris gallopavo	90.34	0.00e+00	6829.00
IUUC-Mmr-060868	Microcebus murinus	84.87	0.00e+00	6364.00
IUUC-Mdo-062772	Monodelphis domestica	87.90	0.00e+00	6674.00
IUUC-Mmu-063606	Mus musculus	87.82	0.00e+00	5091.00
IUUC-Mpu-065860	Mustela putorius furo	87.86	0.00e+00	4815.00
IUUC-Mlu-067376	Myotis lucifugus	90.16	0.00e+00	4931.00
IUUC-Nle-069693	Nomascus leucogenys	88.03	0.00e+00	6549.00
IUUC-Opr-071065	Ochotona princeps	78.37	0.00e+00	961.00
IUUC-Ont-072470	Oreochromis niloticus	80.92	0.00e+00	4447.00
IUUC-Oan-073693	Ornithorhynchus anatinus	93.79	0.00e+00	3374.00
IUUC-Ocu-074032	Oryctolagus cuniculus	87.60	0.00e+00	6628.00
IUUC-Ola-087433	Oryzias latipes	82.83	0.00e+00	1576.00
IUUC-Oga-088546	Otolemur garnettii	89.01	0.00e+00	6351.00
IUUC-Oar-089643	Ovis aries	86.24	0.00e+00	721.00
IUUC-Ptr-090504	Pan troglodytes	89.29	0.00e+00	6688.00
IUUC-Pan-092543	Papio anubis	88.05	0.00e+00	6609.00
IUUC-Psi-093952	Pelodiscus sinensis	89.07	0.00e+00	6720.00
IUUC-Pfo-096356	Poecilia formosa	77.74	0.00e+00	5992.00
IUUC-Pab-098240	Pongo abelii	88.22	0.00e+00	6612.00
IUUC-Pca-100994	Procavia capensis	89.26	0.00e+00	2714.00
IUUC-Pva-102263	Pteropus vampyrus	89.63	0.00e+00	4873.00
IUUC-Rno-104888	Rattus norvegicus	87.78	0.00e+00	5104.00
IUUC-Sha-106944	Sarcophilus harrisii	88.30	0.00e+00	6719.00
IUUC-Sar-113556	Sorex araneus	83.36	0.00e+00	931.00
IUUC-Ssc-116187	Sus scrofa	90.52	0.00e+00	4857.00
IUUC-Tgu-116655	Taeniopygia guttata	91.96	0.00e+00	5171.00
IUUC-Tru-118093	Takifugu rubripes	83.67	0.00e+00	2992.00
IUUC-Tni-119739	Tetraodon nigroviridis	83.05	0.00e+00	1606.00
IUUC-Tbe-127962	Tupaia belangeri	78.36	0.00e+00	1049.00
IUUC-Ttr-128819	Tursiops truncatus	83.66	0.00e+00	2607.00
IUUC-Vpa-130482	Vicugna pacos	91.25	0.00e+00	3094.00
IUUC-Xtr-132222	Xenopus tropicalis	85.13	0.00e+00	6428.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence