iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSBTAG00000014827.5	ENSBTAT00000033922.2	ENSBTAP00000033825.2
ENSBTAG00000014827.5	ENSBTAT00000019747.5	ENSBTAP00000019747.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	4.90e-10	39.4	547	584
ULD/UDP/UBQ/UBQ_PIM	4.90e-25	87.4	37	110

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGF.dreealqaLraannnleaAveyLl 39
           ++++leql +MGF +re++lqaL a++++++aA+e+Ll
   Q: 547  FQQQLEQLSAMGFlNREANLQALIATGGDINAAIERLL 584
           799**********************************9 PP

ULD/UDP/UBQ/UBQ_PIM

   S: 1    mkltvktlkgkefelevseddtveelKekiakesgvppeqqkLIyaGkiLkDdttLselgikdgsvvhlvvkksk 75
           mk+tvkt+k+ke e+ v e+++v+++Ke+i+k+++ + +q+ LI+aGkiLkD++tLs++gi+dg +vhlv+k+++
   Q: 37   MKVTVKTPKEKE-EFAVPENSSVQQFKEEISKRFKSHTDQLVLIFAGKILKDQDTLSQHGIHDGLTVHLVIKTQN 110
           99**********.***********************************************************987 PP

Organism

Bos taurus

Protein Sequence
(Fasta)

MAENSESGGP PSSQDNAAAA EGAGAPAATA STEPKIMKVT VKTPKEKEEF AVPENSSVQQ 60
FKEEISKRFK SHTDQLVLIF AGKILKDQDT LSQHGIHDGL TVHLVIKTQN RPQDHSAQQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTCTGAACAC ACAGCGGCTG CTGAGCGCCC GACCAGGGCC TGCGCCGGAG CCCACGCCAA 60
GCTCCGCGGC TCCTCGCCCA CCAGGGCGGC CCTGAGCCAG TTGTCACTGA GGTAGCGCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006636--STI1_HS-bd
IPR015940--UBA
IPR009060--UBA-like
IPR015496--Ubiquilin
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom

PROSITE

PS50030--UBA
PS50053--UBIQUITIN_2

Pfam

PF00627--UBA
PF00240--ubiquitin

SMART

SM00727--STI1
SM00165--UBA
SM00213--UBQ

Gene Ontology

GO:0016235--C:aggresome
GO:0005776--C:autophagosome
GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0005654--C:nucleoplasm
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0043234--C:protein complex
GO:0035973--P:aggrephagy
GO:0000045--P:autophagosome assembly
GO:0097352--P:autophagosome maturation
GO:0071456--P:cellular response to hypoxia
GO:1901340--P:negative regulation of store-operated calcium channel activity
GO:0034140--P:negative regulation of toll-like receptor 3 signaling pathway
GO:1903071--P:positive regulation of ER-associated ubiquitin-dependent protein catabolic process
GO:0031398--P:positive regulation of protein ubiquitination
GO:1902175--P:regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

bta:282392

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000864	Aegilops tauschii	49.65	6.00e-38	152.00
IUUC-Aml-001461	Ailuropoda melanoleuca	96.21	0.00e+00	810.00
IUUC-Atr-002470	Amborella trichopoda	40.66	6.00e-44	172.00
IUUC-Apl-003241	Anas platyrhynchos	83.33	0.00e+00	717.00
IUUC-Aca-004511	Anolis carolinensis	80.95	0.00e+00	724.00
IUUC-Aly-005419	Arabidopsis lyrata	33.79	3.00e-50	192.00
IUUC-Ath-007350	Arabidopsis thaliana	34.47	5.00e-51	195.00
IUUC-Ago-007963	Ashbya gossypii	37.68	1.00e-08	53.90
IUUC-Bdi-014506	Brachypodium distachyon	35.75	1.00e-50	194.00
IUUC-Bol-015326	Brassica oleracea	32.93	2.00e-49	189.00
IUUC-Bra-018014	Brassica rapa	38.06	2.00e-40	160.00
IUUC-Cel-018631	Caenorhabditis elegans	38.35	2.00e-67	249.00
IUUC-Cja-019976	Callithrix jacchus	95.31	0.00e+00	832.00
IUUC-Cfa-020092	Canis familiaris	96.56	0.00e+00	838.00
IUUC-Cpo-022388	Cavia porcellus	93.49	0.00e+00	811.00
IUUC-Csa-024087	Chlorocebus sabaeus	95.81	0.00e+00	834.00
IUUC-Cho-024834	Choloepus hoffmanni	95.41	0.00e+00	841.00
IUUC-Cin-025136	Ciona intestinalis	50.55	5.00e-114	404.00
IUUC-Cme-027155	Cyanidioschyzon merolae	58.10	1.00e-34	140.00
IUUC-Dno-028970	Dasypus novemcinctus	76.38	0.00e+00	649.00
IUUC-Dor-030519	Dipodomys ordii	92.60	0.00e+00	789.00
IUUC-Dme-032013	Drosophila melanogaster	46.39	9.00e-114	404.00
IUUC-Ete-032273	Echinops telfairi	94.31	0.00e+00	805.00
IUUC-Eca-033667	Equus caballus	94.72	0.00e+00	843.00
IUUC-Eeu-034865	Erinaceus europaeus	70.67	2.00e-158	551.00
IUUC-Fca-036179	Felis catus	93.68	0.00e+00	790.00
IUUC-Fal-037642	Ficedula albicollis	82.71	0.00e+00	776.00
IUUC-Gga-041264	Gallus gallus	83.75	0.00e+00	809.00
IUUC-Gma-042681	Glycine max	35.31	1.00e-43	171.00
IUUC-Ggo-044969	Gorilla gorilla	95.48	0.00e+00	809.00
IUUC-Hsa-046669	Homo sapiens	95.66	0.00e+00	842.00
IUUC-Itr-048337	Ictidomys tridecemlineatus	95.52	0.00e+00	679.00
IUUC-Lch-050192	Latimeria chalumnae	78.29	0.00e+00	675.00
IUUC-Lpe-051401	Leersia perrieri	35.43	8.00e-36	145.00
IUUC-Loc-052846	Lepisosteus oculatus	76.80	0.00e+00	667.00
IUUC-Laf-054278	Loxodonta africana	95.14	0.00e+00	792.00
IUUC-Mcc-055680	Macaca mulatta	96.20	0.00e+00	842.00
IUUC-Meu-056207	Macropus eugenii	75.56	1.00e-171	595.00
IUUC-Mga-059894	Meleagris gallopavo	82.99	0.00e+00	649.00
IUUC-Mmr-061094	Microcebus murinus	95.66	0.00e+00	818.00
IUUC-Mdo-062728	Monodelphis domestica	84.97	0.00e+00	768.00
IUUC-Mmu-064088	Mus musculus	85.08	0.00e+00	819.00
IUUC-Mac-065526	Musa acuminata	40.00	1.00e-44	174.00
IUUC-Mpu-066282	Mustela putorius furo	92.60	0.00e+00	802.00
IUUC-Mlu-068158	Myotis lucifugus	94.76	0.00e+00	798.00
IUUC-Nle-069321	Nomascus leucogenys	95.48	0.00e+00	842.00
IUUC-Opr-071098	Ochotona princeps	87.94	4.00e-180	624.00
IUUC-Oan-072808	Ornithorhynchus anatinus	86.59	0.00e+00	741.00
IUUC-Ocu-074301	Oryctolagus cuniculus	86.78	0.00e+00	786.00
IUUC-Oba-074973	Oryza barthii	36.42	2.00e-40	160.00
IUUC-Obr-076444	Oryza brachyantha	50.34	1.00e-32	134.00
IUUC-Ogl-077319	Oryza glaberrima	36.42	3.00e-41	162.00
IUUC-Oin-079142	Oryza indica	36.42	9.00e-41	161.00
IUUC-Olo-080565	Oryza longistaminata	37.59	1.00e-40	160.00
IUUC-Ome-081155	Oryza meridionalis	51.55	4.00e-34	139.00
IUUC-Oni-082272	Oryza nivara	36.42	9.00e-41	161.00
IUUC-Oru-085257	Oryza rufipogon	36.42	9.00e-41	161.00
IUUC-Osa-086257	Oryza sativa	36.42	3.00e-41	162.00
IUUC-Olu-087597	Ostreococcus lucimarinus	33.21	5.00e-25	108.00
IUUC-Oga-088495	Otolemur garnettii	95.48	0.00e+00	797.00
IUUC-Oar-089711	Ovis aries	98.15	0.00e+00	820.00
IUUC-Ptr-091439	Pan troglodytes	95.30	0.00e+00	836.00
IUUC-Pan-092641	Papio anubis	96.20	0.00e+00	842.00
IUUC-Psi-093518	Pelodiscus sinensis	83.46	0.00e+00	714.00
IUUC-Pma-094727	Petromyzon marinus	42.01	2.00e-50	193.00
IUUC-Ppa-095702	Physcomitrella patens	34.74	1.00e-45	177.00
IUUC-Pfo-096638	Poecilia formosa	67.08	1.00e-174	606.00
IUUC-Pab-098699	Pongo abelii	93.31	0.00e+00	834.00
IUUC-Pop-099549	Populus trichocarpa	37.56	3.00e-53	202.00
IUUC-Pca-100497	Procavia capensis	84.00	2.00e-132	466.00
IUUC-Pva-102513	Pteropus vampyrus	83.04	2.00e-147	515.00
IUUC-Pgr-103261	Puccinia graminis	54.76	2.00e-07	50.10
IUUC-Rno-104908	Rattus norvegicus	85.59	0.00e+00	850.00
IUUC-Sha-106881	Sarcophilus harrisii	83.03	0.00e+00	711.00
IUUC-Smo-109502	Selaginella moellendorffii	35.81	5.00e-38	152.00
IUUC-Sar-113648	Sorex araneus	88.52	0.00e+00	633.00
IUUC-Sbi-114307	Sorghum bicolor	38.13	6.00e-43	168.00
IUUC-Ssc-115820	Sus scrofa	97.47	0.00e+00	840.00
IUUC-Tgu-116845	Taeniopygia guttata	77.07	0.00e+00	697.00
IUUC-Tni-119780	Tetraodon nigroviridis	65.25	4.00e-170	591.00
IUUC-Tca-121558	Theobroma cacao	49.42	3.00e-43	169.00
IUUC-Tae-125518	Triticum aestivum	49.65	2.00e-38	153.00
IUUC-Tur-126248	Triticum urartu	49.65	3.00e-38	153.00
IUUC-Tbe-127379	Tupaia belangeri	82.77	0.00e+00	661.00
IUUC-Ttr-128630	Tursiops truncatus	95.08	0.00e+00	852.00
IUUC-Vpa-130413	Vicugna pacos	71.99	7.00e-160	556.00
IUUC-Vvi-131599	Vitis vinifera	39.52	1.00e-40	160.00
IUUC-Xtr-132595	Xenopus tropicalis	80.36	0.00e+00	701.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence