iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118135

UUCD1 version

UUC-TaR-01159

Ensembl Protein ID

ENSTRUP00000000039.1

UniProt Accession

H2RIS6; H2RIS6_TAKRU

Protein Name

Uncharacterized protein

Gene Name

usp25

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000000019.1	ENSTRUT00000000039.1	ENSTRUP00000000039.1
ENSTRUG00000000019.1	ENSTRUT00000000040.1	ENSTRUP00000000040.1
ENSTRUG00000000019.1	ENSTRUT00000000041.1	ENSTRUP00000000041.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.50e-62	213.0	168	651

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs 85
           +GlkN+gNtC++ +v+Q+L+n+ e+++l+l+     k  +l+++++++++ +++++l++lf+ ++ sk+k+v+p++ +++lk++ ++ s
   Q: 168  VGLKNVGNTCWFSAVIQSLFNLLEFQRLVLNysppLKVPDLPRNQKEHRNLPFMQELRNLFSLMVGSKRKYVDPSRAVEILKDAFKS-S 255
           6******************************97776666777777788899*******************************99998.9 PP
   S: 86   gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           +++qqD++Ef++ lld le+++++                  + +ee+++++ k+++++lF g++    + +   ++ +  e f +++l
   Q: 256  ESQQQDVSEFTHKLLDWLEDAFQM------------------QAEEESETERPKNPMVELFYGHFLAVGVLEG--KKFENSEMFGQYPL 324
           9*********************32..................2345788999**************8777754..44556899****** PP
   S: 175  pvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlsp 263
           +v+g +     +l++cLe+ ++e e+e+   ++ e+ +   ++ +++++++lP+vL+++L+Rf+f+++ +++eki++k+efp ++ +++
   Q: 325  QVNGFK-----DLHECLEAAMNEGEIES---LSAENST---RSGQEHWFTELPPVLTFELSRFEFNQALGRPEKIHNKLEFPSMIYMDR 402
           ******.....9**************96...6666654...5678******************************************** PP
   S: 264  fcts..................................................................................... 267
           ++ +                                                                                     
   Q: 403  YMDKnreitrikreeirrlkehlsllqqrieryvcygsgpkrlpladvlqyalefasskpvctspvedidpsappggatgpllpsssvq 491
           ****8888888888888888888888888888888888888888888888888777777777777777777777777777777666666 PP
   S: 268  .............peekqke..................................................................... 274
                        p     +                                                                     
   Q: 492  qecsppsgpttapP-----Tgqqqriaihkpftqsrlppdlpvhpaprhitkqelqvlesclhrwrsevendihdlqgsinrihrtiel 575
           66666555555551.....0555556666666666666677777777777777777777888888888888888888888888888888 PP
   S: 275  ........kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                   ++ Y+L+av+vH+G+++ GHY+ay+++ +++ W++++D +Vt+++++e ++++      ++aY+l+Y 
   Q: 576  mysdksimQVPYRLHAVLVHEGQANAGHYWAYIYDPRQHcWMKYNDITVTKSSWQELVRDSFggyrnASAYCLMYI 651
           88888888***************************77767****************9997779************6 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MTVEQNVLQQ HAQKHQQTLL NQLKEITGTT DVHLLQEALQ VSNGDMTEAV AFLTEKNAQV 60
SHQDKTSYYQ TSQVTSDRYI SVGSQADTNV IDLTGEDKDD LQRAIALSLA ESDRAYRETG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCGTGG AACAAAATGT CCTCCAGCAA CATGCTCAGA AGGTAAGCTC AGAGGAATGC 60
GCGGCCAGCC CGTGCGCGCC TGTGCGTGTG CGCGTTAGCG GCTCAACACC GACCGTTTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR003903--UIM_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS50330--UIM
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH
PF02809--UIM

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0009953--P:dorsal/ventral pattern formation
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001340	Ailuropoda melanoleuca	68.38	0.00e+00	1479.00
IUUC-Apl-004030	Anas platyrhynchos	68.22	0.00e+00	1500.00
IUUC-Aca-004753	Anolis carolinensis	53.14	0.00e+00	809.00
IUUC-Ani-009503	Aspergillus nidulans	33.02	9.00e-11	62.80
IUUC-Ame-010624	Astyanax mexicanus	68.81	0.00e+00	1054.00
IUUC-Bta-013166	Bos taurus	67.25	0.00e+00	1423.00
IUUC-Cja-019150	Callithrix jacchus	66.22	0.00e+00	1461.00
IUUC-Cfa-020649	Canis familiaris	66.52	0.00e+00	1467.00
IUUC-Cpo-021807	Cavia porcellus	67.61	0.00e+00	1507.00
IUUC-Csa-023388	Chlorocebus sabaeus	65.77	0.00e+00	1459.00
IUUC-Cin-025302	Ciona intestinalis	37.73	2.00e-97	349.00
IUUC-Cgl-026575	Colletotrichum gloeosporioides	55.32	1.00e-10	62.40
IUUC-Dre-028016	Danio rerio	78.45	0.00e+00	1212.00
IUUC-Dno-029495	Dasypus novemcinctus	64.12	0.00e+00	1439.00
IUUC-Dor-030948	Dipodomys ordii	57.57	0.00e+00	999.00
IUUC-Fca-035876	Felis catus	67.60	0.00e+00	1447.00
IUUC-Fal-036762	Ficedula albicollis	73.72	0.00e+00	969.00
IUUC-Fox-037752	Fusarium oxysporum	24.03	2.00e-15	78.60
IUUC-Gmo-039490	Gadus morhua	74.47	0.00e+00	1586.00
IUUC-Gga-040817	Gallus gallus	66.55	0.00e+00	1492.00
IUUC-Gac-042473	Gasterosteus aculeatus	76.68	0.00e+00	1653.00
IUUC-Ggo-044939	Gorilla gorilla	67.46	0.00e+00	1449.00
IUUC-Hsa-046204	Homo sapiens	67.74	0.00e+00	1457.00
IUUC-Kpa-049349	Komagataella pastoris	26.52	6.00e-10	60.50
IUUC-Lch-049572	Latimeria chalumnae	66.40	0.00e+00	1427.00
IUUC-Loc-052070	Lepisosteus oculatus	72.24	0.00e+00	1565.00
IUUC-Lma-053078	Leptosphaeria maculans	31.48	2.00e-12	68.90
IUUC-Laf-054426	Loxodonta africana	66.60	0.00e+00	1349.00
IUUC-Mcc-055858	Macaca mulatta	66.13	0.00e+00	1483.00
IUUC-Mga-059808	Meleagris gallopavo	68.07	0.00e+00	1482.00
IUUC-Mmr-060987	Microcebus murinus	65.95	0.00e+00	1447.00
IUUC-Mmu-064245	Mus musculus	66.51	0.00e+00	1461.00
IUUC-Mpu-066304	Mustela putorius furo	66.10	0.00e+00	1453.00
IUUC-Mlu-067139	Myotis lucifugus	66.98	0.00e+00	1460.00
IUUC-Nle-069075	Nomascus leucogenys	67.65	0.00e+00	1451.00
IUUC-Ont-072150	Oreochromis niloticus	70.74	0.00e+00	1594.00
IUUC-Oan-073054	Ornithorhynchus anatinus	64.22	0.00e+00	1355.00
IUUC-Ocu-074102	Oryctolagus cuniculus	63.84	0.00e+00	1444.00
IUUC-Ola-086529	Oryzias latipes	73.55	0.00e+00	1595.00
IUUC-Oga-088939	Otolemur garnettii	67.29	0.00e+00	1430.00
IUUC-Oar-090266	Ovis aries	65.86	0.00e+00	1427.00
IUUC-Ptr-090546	Pan troglodytes	67.74	0.00e+00	1457.00
IUUC-Pan-092311	Papio anubis	66.04	0.00e+00	1481.00
IUUC-Psi-093459	Pelodiscus sinensis	79.26	0.00e+00	1036.00
IUUC-Pfo-096726	Poecilia formosa	72.17	0.00e+00	1609.00
IUUC-Pab-097608	Pongo abelii	68.03	0.00e+00	1456.00
IUUC-Pca-100718	Procavia capensis	61.35	0.00e+00	1026.00
IUUC-Pva-103150	Pteropus vampyrus	65.10	0.00e+00	1083.00
IUUC-Rno-105727	Rattus norvegicus	66.91	0.00e+00	1448.00
IUUC-Sce-106441	Saccharomyces cerevisiae	32.65	2.00e-09	58.50
IUUC-Sha-107051	Sarcophilus harrisii	67.66	0.00e+00	1450.00
IUUC-Sar-113097	Sorex araneus	62.29	0.00e+00	1321.00
IUUC-Ssc-115877	Sus scrofa	65.78	0.00e+00	1418.00
IUUC-Tgu-117473	Taeniopygia guttata	64.22	0.00e+00	1386.00
IUUC-Tsy-119471	Tarsius syrichta	65.10	0.00e+00	1302.00
IUUC-Tni-120139	Tetraodon nigroviridis	78.43	0.00e+00	1582.00
IUUC-Tbe-127549	Tupaia belangeri	63.77	0.00e+00	1352.00
IUUC-Ttr-128896	Tursiops truncatus	64.04	0.00e+00	1353.00
IUUC-Vda-129742	Verticillium dahliae	22.92	1.00e-14	75.90
IUUC-Vpa-130500	Vicugna pacos	73.71	0.00e+00	1056.00
IUUC-Xtr-132896	Xenopus tropicalis	66.24	0.00e+00	1466.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence