iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-021753

Ensembl Protein ID

ENSCPOP00000006818.2

UniProt Accession

H0VAE0; H0VAE0_CAVPO

Genbank Protein ID

ENSCPOP00000006818

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02037551

Gene Name

OPTN

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000007560.3	ENSCPOT00000007633.2	ENSCPOP00000006818.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBAN	2.30e-21	75.5	450	504

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBAN

   S: 1    keelletvevLkqQveiYkeDFqaERadRErlneekeeLqeqveklqkqvsklnd 55
           +ee l+t+ vL++Q++iY++DF+aERa+RE+l+eeke+L+ q++ l+k+++++++
   Q: 450  QEEELDTIAVLRAQMDIYCSDFHAERAAREKLHEEKEQLALQLAILLKENNAFEE 504
           6899************************************************975 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MSHQPLSCLT EKGDSPGETT GNGPPSLAHP NLDTFTPEEL LQQMKELLAE NHQLKEAMKL 60
NNQAMKGRFE ELSAWTEKQK EERQFFEIQS KEAKERLMAL SHENEKLKEE LEKLRGDPQR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCCCACC AGCCTCTCAG CTGCCTGACT GAAAAGGGGG ACAGCCCTGG TGAAACCACA 60
GGGAATGGAC CTCCCAGCCT GGCTCACCCC AACCTGGACA CCTTCACCCC GGAGGAGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032419--CC2-LZ_dom
IPR021063--NEMO_N
IPR032939--Optineurin
IPR034735--ZF_CCHC_NOA

PROSITE

PS51801--ZF_CCHC_NOA

Pfam

PF16516--CC2-LZ
PF11577--NEMO

Gene Ontology

GO:0031410--C:cytoplasmic vesicle
GO:0005829--C:cytosol
GO:0048471--C:perinuclear region of cytoplasm
GO:0005802--C:trans-Golgi network
GO:0050829--P:defense response to Gram-negative bacterium
GO:0090161--P:Golgi ribbon formation
GO:0043001--P:Golgi to plasma membrane protein transport
GO:0016236--P:macroautophagy
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0001920--P:negative regulation of receptor recycling
GO:0061734--P:parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization
GO:1904417--P:positive regulation of xenophagy
GO:0000042--P:protein targeting to Golgi

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002037	Ailuropoda melanoleuca	80.47	0.00e+00	770.00
IUUC-Apl-003812	Anas platyrhynchos	54.36	3.00e-140	491.00
IUUC-Aca-004625	Anolis carolinensis	53.90	9.00e-137	480.00
IUUC-Aly-005781	Arabidopsis lyrata	55.00	2.20e-02	33.50
IUUC-Ath-007558	Arabidopsis thaliana	32.35	4.10e-01	28.90
IUUC-Ame-011116	Astyanax mexicanus	48.79	9.00e-55	207.00
IUUC-Bta-013240	Bos taurus	79.34	0.00e+00	835.00
IUUC-Cel-018324	Caenorhabditis elegans	45.83	1.30e+00	27.70
IUUC-Cja-019911	Callithrix jacchus	80.41	0.00e+00	806.00
IUUC-Cfa-020330	Canis familiaris	81.42	0.00e+00	816.00
IUUC-Csa-023662	Chlorocebus sabaeus	81.79	0.00e+00	817.00
IUUC-Cho-024574	Choloepus hoffmanni	65.33	1.00e-120	426.00
IUUC-Cme-027299	Cyanidioschyzon merolae	35.80	1.20e-01	31.20
IUUC-Dre-027720	Danio rerio	40.61	2.00e-86	312.00
IUUC-Dno-029079	Dasypus novemcinctus	77.78	0.00e+00	753.00
IUUC-Dor-030890	Dipodomys ordii	78.35	0.00e+00	807.00
IUUC-Ete-032568	Echinops telfairi	75.76	0.00e+00	674.00
IUUC-Eca-033528	Equus caballus	80.58	0.00e+00	811.00
IUUC-Eeu-035219	Erinaceus europaeus	72.02	0.00e+00	749.00
IUUC-Fca-035852	Felis catus	79.93	0.00e+00	808.00
IUUC-Fal-036862	Ficedula albicollis	56.33	3.00e-137	481.00
IUUC-Gmo-038735	Gadus morhua	38.62	1.00e-69	256.00
IUUC-Gga-040939	Gallus gallus	53.50	3.00e-140	491.00
IUUC-Gac-041580	Gasterosteus aculeatus	43.59	2.00e-94	339.00
IUUC-Ggo-045034	Gorilla gorilla	73.61	0.00e+00	755.00
IUUC-Hsa-046624	Homo sapiens	80.41	0.00e+00	833.00
IUUC-Itr-048288	Ictidomys tridecemlineatus	74.02	0.00e+00	775.00
IUUC-Lch-049720	Latimeria chalumnae	49.50	5.00e-76	278.00
IUUC-Loc-052185	Lepisosteus oculatus	45.33	2.00e-100	359.00
IUUC-Laf-054079	Loxodonta africana	78.31	0.00e+00	780.00
IUUC-Mcc-055674	Macaca mulatta	82.81	0.00e+00	820.00
IUUC-Meu-056769	Macropus eugenii	78.92	6.00e-66	245.00
IUUC-Mga-060203	Meleagris gallopavo	53.91	2.00e-131	462.00
IUUC-Mmr-061492	Microcebus murinus	80.56	0.00e+00	810.00
IUUC-Mdo-063051	Monodelphis domestica	72.74	0.00e+00	753.00
IUUC-Mmu-063409	Mus musculus	74.79	0.00e+00	814.00
IUUC-Mpu-065907	Mustela putorius furo	74.87	0.00e+00	785.00
IUUC-Mlu-066957	Myotis lucifugus	78.99	0.00e+00	744.00
IUUC-Nle-069973	Nomascus leucogenys	80.96	0.00e+00	832.00
IUUC-Opr-071049	Ochotona princeps	75.73	0.00e+00	716.00
IUUC-Ont-071915	Oreochromis niloticus	43.49	1.00e-88	320.00
IUUC-Oan-072965	Ornithorhynchus anatinus	70.69	0.00e+00	717.00
IUUC-Ocu-074029	Oryctolagus cuniculus	71.72	0.00e+00	654.00
IUUC-Ola-087019	Oryzias latipes	41.22	9.00e-85	307.00
IUUC-Oga-088613	Otolemur garnettii	81.82	0.00e+00	832.00
IUUC-Oar-090386	Ovis aries	80.03	0.00e+00	843.00
IUUC-Ptr-091619	Pan troglodytes	80.24	0.00e+00	830.00
IUUC-Pan-092178	Papio anubis	80.85	0.00e+00	806.00
IUUC-Psi-093214	Pelodiscus sinensis	60.14	9.00e-154	536.00
IUUC-Pfo-096901	Poecilia formosa	40.73	7.00e-82	297.00
IUUC-Pab-097560	Pongo abelii	73.96	0.00e+00	727.00
IUUC-Pca-100853	Procavia capensis	70.06	6.00e-115	407.00
IUUC-Pva-102255	Pteropus vampyrus	77.64	0.00e+00	740.00
IUUC-Rno-105812	Rattus norvegicus	76.36	0.00e+00	819.00
IUUC-Sha-107225	Sarcophilus harrisii	77.03	6.00e-150	523.00
IUUC-Sar-113736	Sorex araneus	69.81	9.00e-120	424.00
IUUC-Ssc-115422	Sus scrofa	80.73	0.00e+00	846.00
IUUC-Tgu-116924	Taeniopygia guttata	55.76	9.00e-134	470.00
IUUC-Tru-117695	Takifugu rubripes	39.76	6.00e-87	314.00
IUUC-Tsy-119090	Tarsius syrichta	79.94	2.00e-140	492.00
IUUC-Tni-120645	Tetraodon nigroviridis	42.28	3.00e-88	319.00
IUUC-Tbe-127970	Tupaia belangeri	65.74	1.00e-120	427.00
IUUC-Ttr-129244	Tursiops truncatus	78.72	0.00e+00	768.00
IUUC-Vpa-130313	Vicugna pacos	76.78	0.00e+00	748.00
IUUC-Xtr-132115	Xenopus tropicalis	44.53	6.00e-91	328.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence