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Tag Content
UUCD2 ID IUUC-Mlu-067294
UUCD1 version UUC-MyL-01160
Ensembl Protein ID ENSMLUP00000006338.2
UniProt Accession G1P857; G1P857_MYOLU
Genbank Protein ID ENSMLUP00000006338
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AAPE02050576
Gene Name USP20
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000006914.2 ENSMLUT00000006934.2 ENSMLUP00000006338.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 9.50e-111 370.3 145 684
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsgye 88
           tG+kNlgN+CYmN++LQ+Lsn+p+l++++le     +    ++++k +l+ks+qkl++e+w  ++ ++v p++l + +k ++++f+gy+
   Q: 145  TGMKNLGNSCYMNAALQALSNCPPLTQFFLE-----CGGLVRTDKKPALCKSYQKLVSEVWhRKRPSYVVPTSLSHGIKLVNPMFRGYA 228
           7******************************.....999999*******************889999********************** PP
   S: 89   qqDaqEflaflldqleeelkk..............eknkpkeeeeeedkselsde.................................. 129
           qqD+qEfl++l+dql+eelk+              +           d   lsd+                                  
   Q: 229  QQDTQEFLRCLMDQLHEELKEpvvavaaalteardS-----------D---LSDSdekregdrspsedeflscdsssdrgegggqgrge 303
           *******************99777444444333332...........3...333333366666677777******************** PP
   S: 130  ......................................................................................... 129
                                                                                                    
   Q: 304  ggsaeaelligdeagraisekermkdrkfswgqqrtsseqvdedadvdtalaaldprppeaqppsprsaspcrtpepdneahmrsasrp 392
           ***************************************************************************************** PP
   S: 130  ........................................aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
                                                   ++++k+++++s+isd+F+g++ s ++cl+cd+vs++ e+f+dlslp+pg
   Q: 393  cspvhhheghtklassppraspvrmgpayvlkkaqgpstgSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPG 481
           ***************************************************************************************** PP
   S: 179  keetkke.................................................slqdcLesftkeeelegenkyycekckkkqeae 218
           ke+ +k+                                                 +l+dcL++f++++el+g+n+y+ce+ckk+++ +
   Q: 482  KEDLAKLhsaiyqnapakpgscgdsyaaqgwlafimeyirrfvvsctpswfwgpviTLEDCLAAFFAADELKGDNMYSCERCKKLRNGV 570
           **99888********************************************************************************** PP
   S: 219  kklklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkn.ekgk 305
           k +k+ +lPe+L++hLkRf  ++e + + ki+++v+fple Ldl+pf+++++++q   ++Y+L++v++H+G+++sGHY+ay++n  +g+
   Q: 571  KYCKVLRLPEILCIHLKRF--RHEVMYSFKISSHVSFPLEgLDLRPFLAKECTSQ--ITTYDLLSVICHHGTAGSGHYIAYCQNvINGQ 655
           *******************..9999***************************999..9**************************78999 PP
   S: 306  WllfdDskVtevkeeevleetgstaYvlfYkr 337
           W++fdD++Vtev+e+ v++   s+aYvlfY++
   Q: 656  WYEFDDQYVTEVHETVVQS---SEAYVLFYRK 684
           *******************...********98 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
MGDSRDLCPH LDSIGEVTKD DLLLKSKGAC QSCGVSGPNL WACLQVACPY VGCGESFADH 60
STLHAQAQKH NLTVNLTTFR VWCYACEKEV FPEQRLAAPL PAASPRLFEQ DSPLPSHPLK 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-067294|DUB,USP|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGGGACT CCAGGGACCT TTGCCCTCAC CTTGACTCCA TAGGGGAGGT GACCAAAGAC 60
GACTTGCTGC TCAAATCTAA GGTAAAGGCT CAGACATGGC GGGGCCGAGG CCCACGCTCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-067294|DUB,USP|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF06337--DUSP
PF00443--UCH
PF02148--zf-UBP
SMART

SM00695--DUSP
SM00290--ZnF_UBP
Gene Ontology

GO:0005813--C:centrosome
GO:0004197--F:cysteine-type endopeptidase activity
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:0071108--P:protein K48-linked deubiquitination
GO:0070536--P:protein K63-linked deubiquitination
GO:0008277--P:regulation of G-protein coupled receptor protein signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002209 Ailuropoda melanoleuca 92.46 0.00e+00 1668.00
IUUC-Apl-003351 Anas platyrhynchos 84.35 0.00e+00 1555.00
IUUC-Aca-005077 Anolis carolinensis 76.65 0.00e+00 1114.00
IUUC-Ame-011777 Astyanax mexicanus 75.68 0.00e+00 1353.00
IUUC-Bta-013063 Bos taurus 93.66 0.00e+00 1670.00
IUUC-Cja-019868 Callithrix jacchus 92.03 0.00e+00 1699.00
IUUC-Cfa-020761 Canis familiaris 93.22 0.00e+00 1686.00
IUUC-Cpo-022267 Cavia porcellus 86.46 0.00e+00 1555.00
IUUC-Csa-024251 Chlorocebus sabaeus 92.79 0.00e+00 1712.00
IUUC-Cho-024483 Choloepus hoffmanni 97.17 1.00e-124 441.00
IUUC-Csv-025889 Ciona savignyi 43.75 3.00e-35 140.00
IUUC-Dre-028061 Danio rerio 74.26 0.00e+00 1211.00
IUUC-Dno-029423 Dasypus novemcinctus 92.46 0.00e+00 1669.00
IUUC-Dor-030877 Dipodomys ordii 90.33 0.00e+00 1077.00
IUUC-Dme-031837 Drosophila melanogaster 49.45 8.00e-138 484.00
IUUC-Ete-032802 Echinops telfairi 78.06 7.00e-135 474.00
IUUC-Eca-034283 Equus caballus 92.24 0.00e+00 1664.00
IUUC-Eeu-034620 Erinaceus europaeus 89.62 0.00e+00 1178.00
IUUC-Fca-036357 Felis catus 93.44 0.00e+00 1654.00
IUUC-Fal-037411 Ficedula albicollis 85.31 0.00e+00 1558.00
IUUC-Gmo-038563 Gadus morhua 77.18 0.00e+00 834.00
IUUC-Gga-041101 Gallus gallus 84.90 0.00e+00 1550.00
IUUC-Gac-041315 Gasterosteus aculeatus 73.42 0.00e+00 1316.00
IUUC-Ggo-045600 Gorilla gorilla 92.17 0.00e+00 1648.00
IUUC-Hsa-045825 Homo sapiens 92.79 0.00e+00 1664.00
IUUC-Itr-048549 Ictidomys tridecemlineatus 79.49 0.00e+00 1390.00
IUUC-Lch-050002 Latimeria chalumnae 75.19 0.00e+00 1325.00
IUUC-Loc-052574 Lepisosteus oculatus 77.24 0.00e+00 1406.00
IUUC-Laf-054428 Loxodonta africana 91.38 0.00e+00 1650.00
IUUC-Mcc-055736 Macaca mulatta 92.57 0.00e+00 1707.00
IUUC-Mga-059781 Meleagris gallopavo 84.26 0.00e+00 1548.00
IUUC-Mdo-063048 Monodelphis domestica 84.97 0.00e+00 1510.00
IUUC-Mmu-064079 Mus musculus 91.27 0.00e+00 1656.00
IUUC-Mpu-066616 Mustela putorius furo 91.06 0.00e+00 1694.00
IUUC-Nle-070015 Nomascus leucogenys 92.46 0.00e+00 1629.00
IUUC-Opr-070328 Ochotona princeps 90.62 0.00e+00 1655.00
IUUC-Ont-071464 Oreochromis niloticus 75.38 0.00e+00 1308.00
IUUC-Oan-073259 Ornithorhynchus anatinus 78.04 0.00e+00 1296.00
IUUC-Ocu-074630 Oryctolagus cuniculus 88.97 0.00e+00 1581.00
IUUC-Ola-087240 Oryzias latipes 74.30 0.00e+00 1293.00
IUUC-Oga-088761 Otolemur garnettii 90.60 0.00e+00 1665.00
IUUC-Oar-089490 Ovis aries 87.32 0.00e+00 1499.00
IUUC-Ptr-091662 Pan troglodytes 92.79 0.00e+00 1662.00
IUUC-Pan-092199 Papio anubis 92.37 0.00e+00 1699.00
IUUC-Psi-093726 Pelodiscus sinensis 85.39 0.00e+00 1557.00
IUUC-Pma-094389 Petromyzon marinus 63.97 6.00e-99 353.00
IUUC-Pfo-096522 Poecilia formosa 72.18 0.00e+00 949.00
IUUC-Pab-098632 Pongo abelii 92.57 0.00e+00 1654.00
IUUC-Pca-100614 Procavia capensis 84.26 0.00e+00 1287.00
IUUC-Pva-102922 Pteropus vampyrus 89.85 0.00e+00 990.00
IUUC-Rno-105215 Rattus norvegicus 91.04 0.00e+00 1659.00
IUUC-Sce-106176 Saccharomyces cerevisiae 33.33 5.00e-26 112.00
IUUC-Sha-106601 Sarcophilus harrisii 84.32 0.00e+00 1499.00
IUUC-Ssc-115533 Sus scrofa 91.25 0.00e+00 1628.00
IUUC-Tgu-117364 Taeniopygia guttata 85.26 0.00e+00 1534.00
IUUC-Tru-117770 Takifugu rubripes 72.03 0.00e+00 1293.00
IUUC-Tni-120001 Tetraodon nigroviridis 73.25 0.00e+00 1269.00
IUUC-Ttr-128732 Tursiops truncatus 93.55 0.00e+00 1668.00
IUUC-Xtr-132157 Xenopus tropicalis 75.68 0.00e+00 1352.00
Created Date 25-Jun-2017

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