iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cja-019650

UUCD1 version

UUC-CaJ-00972

Ensembl Protein ID

ENSCJAP00000011237.1

UniProt Accession

F7IQE8; F7IQE8_CALJA

Genbank Protein ID

JAB12956.1; JAB12957.1; JAB12958.1; JAB28586.1; JAB39130.1; JAB39131.1; JAB39132.1

Protein Name

Kelch-like protein 8

Genbank Nucleotide ID

ACFV01014503; GAMS01010179; GAMS01010178; GAMR01005346; GAMQ01002721; GAMQ01002720; GAMQ01002719

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000006088.2	ENSCJAT00000011858.1	ENSCJAP00000011237.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.80e-17	62.8	67	132
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.00e-09	36.7	166	197

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + +++hk+vLa   ++F+a+fl+e+ e k +  +ei+d + ++ ++l+kF+Y+++l++
   Q: 67   CDVTLKVGSKLISCHKLVLACVIPYFRAMFLSEMAEAK-QTLIEIRDFDGDAIEDLVKFVYSSRLTL 132
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhFk 32
           ++Ncl++++fA+ ++  dL+d a+ +++ hF+
   Q: 166  PSNCLAVRAFAESHNRIDLMDMADQYACEHFT 197
           89*****************************7 PP

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MASDSVNGKQ VRNHITRGKR QQQHQQIKNR SSISDGDGED SFTFEANEAW KDFHSSLLRF 60
YENGELCDVT LKVGSKLISC HKLVLACVIP YFRAMFLSEM AEAKQTLIEI RDFDGDAIED 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCCGCCA GGGCTCCGCG GGGCCGCCCA GGAGAGCGCG CGTCTGCCGG GTGCTCGAGC 60
GGTTCTGGTG AGGTGCCGCT GAGGGCGGCC GGGTGACGCG GCTGCAGCCT TAGCAACACC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

cjc:100387211

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	97.42	0.00e+00	1241.00
IUUC-Atr-002726	Amborella trichopoda	35.48	6.00e-43	169.00
IUUC-Apl-003978	Anas platyrhynchos	89.37	0.00e+00	1159.00
IUUC-Aca-004958	Anolis carolinensis	84.86	0.00e+00	1087.00
IUUC-Ame-011139	Astyanax mexicanus	82.75	0.00e+00	1065.00
IUUC-Bta-013142	Bos taurus	95.48	0.00e+00	1217.00
IUUC-Cel-018551	Caenorhabditis elegans	41.25	2.00e-130	459.00
IUUC-Cfa-021046	Canis familiaris	97.58	0.00e+00	1239.00
IUUC-Cpo-022445	Cavia porcellus	93.39	0.00e+00	1165.00
IUUC-Csa-023642	Chlorocebus sabaeus	98.71	0.00e+00	1281.00
IUUC-Cho-025012	Choloepus hoffmanni	78.86	0.00e+00	885.00
IUUC-Dre-027723	Danio rerio	81.76	0.00e+00	1058.00
IUUC-Dno-028964	Dasypus novemcinctus	94.93	0.00e+00	1019.00
IUUC-Dor-030899	Dipodomys ordii	82.78	1.00e-136	480.00
IUUC-Ete-032815	Echinops telfairi	91.94	0.00e+00	1201.00
IUUC-Eca-034162	Equus caballus	96.13	0.00e+00	1207.00
IUUC-Eeu-034660	Erinaceus europaeus	93.39	0.00e+00	1192.00
IUUC-Fca-035659	Felis catus	97.58	0.00e+00	1241.00
IUUC-Fal-037619	Ficedula albicollis	90.00	0.00e+00	1173.00
IUUC-Fox-037999	Fusarium oxysporum	31.17	3.00e-08	51.60
IUUC-Gmo-038546	Gadus morhua	84.59	0.00e+00	1050.00
IUUC-Ggr-040041	Gaeumannomyces graminis	31.29	2.00e-07	50.10
IUUC-Gga-040770	Gallus gallus	89.86	0.00e+00	1137.00
IUUC-Gac-042557	Gasterosteus aculeatus	79.17	0.00e+00	1043.00
IUUC-Ggo-044741	Gorilla gorilla	98.39	0.00e+00	1279.00
IUUC-Hsa-046025	Homo sapiens	98.23	0.00e+00	1276.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	97.63	0.00e+00	1104.00
IUUC-Loc-052834	Lepisosteus oculatus	82.39	0.00e+00	1011.00
IUUC-Laf-054513	Loxodonta africana	95.48	0.00e+00	1217.00
IUUC-Mcc-054707	Macaca mulatta	98.55	0.00e+00	1278.00
IUUC-Meu-056779	Macropus eugenii	90.68	0.00e+00	1167.00
IUUC-Mtr-058180	Medicago truncatula	31.54	1.00e-35	145.00
IUUC-Mga-059676	Meleagris gallopavo	89.53	0.00e+00	1134.00
IUUC-Mmr-061359	Microcebus murinus	95.48	0.00e+00	1215.00
IUUC-Mdo-062527	Monodelphis domestica	89.41	0.00e+00	1162.00
IUUC-Mmu-063112	Mus musculus	92.05	0.00e+00	1208.00
IUUC-Mac-064682	Musa acuminata	35.50	2.00e-41	164.00
IUUC-Mpu-065800	Mustela putorius furo	96.94	0.00e+00	1235.00
IUUC-Mlu-067536	Myotis lucifugus	95.77	0.00e+00	1176.00
IUUC-Nle-069397	Nomascus leucogenys	98.55	0.00e+00	1281.00
IUUC-Opr-070599	Ochotona princeps	94.73	0.00e+00	1018.00
IUUC-Ont-072580	Oreochromis niloticus	81.24	0.00e+00	1055.00
IUUC-Oan-073180	Ornithorhynchus anatinus	91.94	0.00e+00	1176.00
IUUC-Ocu-074026	Oryctolagus cuniculus	95.48	0.00e+00	1201.00
IUUC-Obr-076181	Oryza brachyantha	31.60	1.00e-35	145.00
IUUC-Ola-086776	Oryzias latipes	80.72	0.00e+00	1019.00
IUUC-Oga-088651	Otolemur garnettii	96.30	0.00e+00	1221.00
IUUC-Oar-089567	Ovis aries	94.35	0.00e+00	1194.00
IUUC-Ptr-091564	Pan troglodytes	98.39	0.00e+00	1279.00
IUUC-Pan-092578	Papio anubis	98.71	0.00e+00	1281.00
IUUC-Psi-093635	Pelodiscus sinensis	88.44	0.00e+00	1099.00
IUUC-Pma-094660	Petromyzon marinus	61.99	0.00e+00	765.00
IUUC-Pfo-097507	Poecilia formosa	81.74	0.00e+00	984.00
IUUC-Pab-098025	Pongo abelii	98.39	0.00e+00	1279.00
IUUC-Pca-101046	Procavia capensis	86.58	0.00e+00	630.00
IUUC-Ppe-101154	Prunus persica	31.50	1.00e-37	151.00
IUUC-Pva-102359	Pteropus vampyrus	97.50	0.00e+00	905.00
IUUC-Rno-105750	Rattus norvegicus	92.27	0.00e+00	1186.00
IUUC-Sha-107513	Sarcophilus harrisii	91.95	0.00e+00	1196.00
IUUC-Sly-111482	Solanum lycopersicum	31.13	1.00e-40	160.00
IUUC-Stu-112032	Solanum tuberosum	32.30	5.00e-42	166.00
IUUC-Sar-113616	Sorex araneus	70.99	3.00e-118	418.00
IUUC-Ssc-116205	Sus scrofa	95.71	0.00e+00	1030.00
IUUC-Tgu-117435	Taeniopygia guttata	90.16	0.00e+00	1165.00
IUUC-Tru-118709	Takifugu rubripes	80.86	0.00e+00	1056.00
IUUC-Tsy-119466	Tarsius syrichta	97.99	0.00e+00	1104.00
IUUC-Tni-119988	Tetraodon nigroviridis	80.72	0.00e+00	1048.00
IUUC-Tbe-127704	Tupaia belangeri	96.35	0.00e+00	1064.00
IUUC-Ttr-128892	Tursiops truncatus	97.19	0.00e+00	922.00
IUUC-Vpa-130545	Vicugna pacos	96.29	0.00e+00	1036.00
IUUC-Xtr-132289	Xenopus tropicalis	83.85	0.00e+00	1036.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence