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Tag Content
UUCD2 ID IUUC-Pab-098191
UUCD1 version UUC-PoA-01058
Ensembl Protein ID ENSPPYP00000007420.2
UniProt Accession H2NNG0; H2NNG0_PONAB
Genbank Protein ID ENSPPYP00000007420
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID ABGA01297854
Gene Name USP3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPPYG00000006541.2 ENSPPYT00000007724.2 ENSPPYP00000007420.2
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 1.20e-100 337.1 159 510
UBD/ZnF/ZnF_UBP 2.80e-27 94.8 27 104
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalk 78
           tGl+NlgNtC+mN++LQ+Lsni+++ ++++e             +++ + +++ +++ +l+++++k + +lw+++++a+sp++l+ +++
   Q: 159  TGLRNLGNTCFMNAILQSLSNIEQFCCYFKElpavelrngktAGRRTYHTRSQGDNNVSLVEEFRKTLCALWQGSQTAFSPESLFYVVW 247
           7******************************888888777765555555555688889******************************* PP
   S: 79   keaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssree 167
           k+ ++f+gy+qqDa+Ef+++lld+l+ el+   n    ++  +++s+ls  +++   +  +++++ +F+g l++++ cl c+++s +++
   Q: 248  KIMPNFRGYQQQDAHEFMRYLLDHLHLELQGGFNGVSRSAILQENSTLS-ASNKCCINGASTVVTAIFGGILQNEVNCLICGTESRKFD 335
           *****************************77444444444444444444.45688899999**************************** PP
   S: 168  pfldlslpvpgkeetkke.........slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
           pfldlsl++p++  +k +         sl+dcL+sft  eel++ + y c kckkkq+++kk++++klP+vL+lhLkRf+++   + r+
   Q: 336  PFLDLSLDIPSQFRSKRSknqengpvcSLRDCLRSFTDLEELDETELYMCHKCKKKQKSTKKFWIQKLPKVLCLHLKRFHWTA--YLRN 422
           **********77655555678899999****************************************************7755..799* PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlf 334
           k++++vefpl+ Ld++ ++ +pe++  e++ Y+L avvvH+G +++sGHY+ay+ + +g+W++f+Ds+Vt ++ee+v++   ++aY+lf
   Q: 423  KVDTYVEFPLRgLDMKCYLLEPENSGPESCLYDLAAVVVHHGsGVGSGHYTAYATH-EGRWFHFNDSTVTLTDEETVVK---AKAYILF 507
           ********************************************************.9*********************...******* PP
   S: 335  Ykr 337
           Y +
   Q: 508  YVE 510
           *76 PP
   

   UBD/ZnF/ZnF_UBP
   S: 1    kkcsvcdktenlWlcLtcgsvgCGRyvegHalkHyeetqhpl................vlslstlsvycYacddyvhr 62
           ++csvc++++++W+cLtc+sv+CGRyv+gHa+kHye++q+pl                ++++s++s+ycY+cdd+v++
   Q: 27   WCCSVCRSNKSPWVCLTCSSVHCGRYVNGHAKKHYEDAQVPLtnhkksekqdkaqhtvCMDCSSYSTYCYRCDDFVVN 104
           9***************************************************************************85 PP
   
Organism Pongo abelii
Protein Sequence
(Fasta)
MECPHLSSSV CIAPDSAKFP NGSPSSWCCS VCRSNKSPWV CLTCSSVHCG RYVNGHAKKH 60
YEDAQVPLTN HKKSEKQDKA QHTVCMDCSS YSTYCYRCDD FVVNDTKLGL VQKVREHLQN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pab-098191|DUB,USP;UBD,ZnF_UBP|Pongo abelii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCTTGAAAGT CCTACGATGT GCTGGAGGTA ACGCAGATGG TGAGTCACAG TGACAGGGTT 60
TGAATGCGGG TTCGTGGGCG CCCCTGCGGG CCCAGCCACG CAGCATCTAG GTGGCTGGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pab-098191|DUB,USP;UBD,ZnF_UBP|Pongo abelii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0070938--C:contractile ring
GO:0000790--C:nuclear chromatin
GO:0005654--C:nucleoplasm
GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0006281--P:DNA repair
GO:0016578--P:histone deubiquitination
GO:0000278--P:mitotic cell cycle
GO:0031647--P:regulation of protein stability
GO:0006511--P:ubiquitin-dependent protein catabolic process
KEGG pon:100454247
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001537 Ailuropoda melanoleuca 98.27 0.00e+00 959.00
IUUC-Apl-003358 Anas platyrhynchos 95.92 0.00e+00 902.00
IUUC-Aca-004454 Anolis carolinensis 91.60 0.00e+00 825.00
IUUC-Ame-011544 Astyanax mexicanus 76.98 0.00e+00 741.00
IUUC-Bta-012738 Bos taurus 97.70 0.00e+00 938.00
IUUC-Cel-018186 Caenorhabditis elegans 37.08 2.00e-55 209.00
IUUC-Cja-018893 Callithrix jacchus 99.23 0.00e+00 959.00
IUUC-Cfa-020607 Canis familiaris 98.85 0.00e+00 946.00
IUUC-Cpo-021828 Cavia porcellus 96.15 0.00e+00 922.00
IUUC-Csa-023884 Chlorocebus sabaeus 100.00 0.00e+00 788.00
IUUC-Cho-024863 Choloepus hoffmanni 88.27 0.00e+00 817.00
IUUC-Dre-028452 Danio rerio 73.66 0.00e+00 750.00
IUUC-Dno-029531 Dasypus novemcinctus 97.76 0.00e+00 877.00
IUUC-Dor-030913 Dipodomys ordii 89.82 2.00e-178 618.00
IUUC-Ete-032611 Echinops telfairi 92.12 0.00e+00 883.00
IUUC-Eca-033622 Equus caballus 98.78 0.00e+00 882.00
IUUC-Eeu-035268 Erinaceus europaeus 92.43 0.00e+00 801.00
IUUC-Fca-035801 Felis catus 98.16 0.00e+00 910.00
IUUC-Fal-036749 Ficedula albicollis 94.91 0.00e+00 855.00
IUUC-Gmo-039598 Gadus morhua 76.91 0.00e+00 769.00
IUUC-Gga-040883 Gallus gallus 96.12 0.00e+00 869.00
IUUC-Gac-042235 Gasterosteus aculeatus 75.82 0.00e+00 742.00
IUUC-Ggo-044767 Gorilla gorilla 93.89 0.00e+00 848.00
IUUC-Hsa-046581 Homo sapiens 99.42 0.00e+00 983.00
IUUC-Itr-047898 Ictidomys tridecemlineatus 99.04 0.00e+00 949.00
IUUC-Lch-049732 Latimeria chalumnae 91.54 0.00e+00 919.00
IUUC-Loc-052371 Lepisosteus oculatus 89.62 0.00e+00 908.00
IUUC-Laf-054565 Loxodonta africana 98.46 0.00e+00 944.00
IUUC-Mcc-055522 Macaca mulatta 99.81 0.00e+00 989.00
IUUC-Meu-056754 Macropus eugenii 86.30 2.00e-177 615.00
IUUC-Mga-060095 Meleagris gallopavo 94.36 0.00e+00 639.00
IUUC-Mmr-060839 Microcebus murinus 98.85 0.00e+00 946.00
IUUC-Mdo-062339 Monodelphis domestica 97.70 0.00e+00 761.00
IUUC-Mmu-063638 Mus musculus 97.12 0.00e+00 913.00
IUUC-Mpu-066647 Mustela putorius furo 98.62 0.00e+00 765.00
IUUC-Mlu-067921 Myotis lucifugus 97.14 0.00e+00 894.00
IUUC-Nle-069752 Nomascus leucogenys 99.81 0.00e+00 988.00
IUUC-Opr-070636 Ochotona princeps 82.88 0.00e+00 733.00
IUUC-Ont-071638 Oreochromis niloticus 77.05 0.00e+00 702.00
IUUC-Oan-073417 Ornithorhynchus anatinus 90.58 0.00e+00 894.00
IUUC-Ocu-074620 Oryctolagus cuniculus 96.54 0.00e+00 928.00
IUUC-Ola-087281 Oryzias latipes 79.03 0.00e+00 630.00
IUUC-Olu-087697 Ostreococcus lucimarinus 40.33 5.00e-49 187.00
IUUC-Oga-088448 Otolemur garnettii 97.88 0.00e+00 971.00
IUUC-Oar-090132 Ovis aries 97.50 0.00e+00 940.00
IUUC-Ptr-090696 Pan troglodytes 99.59 0.00e+00 925.00
IUUC-Pan-092124 Papio anubis 99.42 0.00e+00 984.00
IUUC-Psi-093801 Pelodiscus sinensis 96.78 0.00e+00 754.00
IUUC-Pma-094472 Petromyzon marinus 71.93 1.00e-94 338.00
IUUC-Pfo-096330 Poecilia formosa 78.50 0.00e+00 783.00
IUUC-Pca-100341 Procavia capensis 96.63 0.00e+00 730.00
IUUC-Pva-103177 Pteropus vampyrus 98.46 0.00e+00 934.00
IUUC-Rno-105048 Rattus norvegicus 95.79 0.00e+00 897.00
IUUC-Sha-107429 Sarcophilus harrisii 96.18 0.00e+00 873.00
IUUC-Sar-113024 Sorex araneus 96.38 0.00e+00 820.00
IUUC-Ssc-115749 Sus scrofa 96.44 5.00e-152 530.00
IUUC-Tgu-117277 Taeniopygia guttata 95.10 0.00e+00 891.00
IUUC-Tru-117844 Takifugu rubripes 78.69 0.00e+00 780.00
IUUC-Tsy-119456 Tarsius syrichta 95.91 0.00e+00 873.00
IUUC-Tni-120251 Tetraodon nigroviridis 74.71 0.00e+00 792.00
IUUC-Tbe-127423 Tupaia belangeri 92.50 0.00e+00 862.00
IUUC-Ttr-128401 Tursiops truncatus 91.21 0.00e+00 795.00
IUUC-Vpa-130549 Vicugna pacos 88.02 1.00e-164 572.00
IUUC-Xtr-131892 Xenopus tropicalis 83.18 0.00e+00 802.00
Created Date 25-Jun-2017

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