iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-051994

Ensembl Protein ID

ENSLOCP00000011887.1

UniProt Accession

W5MU28; W5MU28_LEPOC

Genbank Protein ID

ENSLOCP00000011887

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHAT01012883

Gene Name

ARHGEF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000009733.1	ENSLOCT00000011908.1	ENSLOCP00000011887.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.30e-10	41.3	114	165

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           + ++l+d    +d eL +k+Gdv++v+  + ++++W+ g       +G fP+ Fv+
   Q: 114  YAEALWDHVTMDDQELGFKAGDVIEVV--DATNKEWWWG--RILDSEGWFPASFVR 165
           5789***********************..9999******..89999********97 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MGRLAVELPE ELEKVRARLS LTPAVPFPTL PLKDHCFSQS TPIGLDCLGW RRRISYPAVI 60
PDGASDRTGL GDDVGSEEDL YEDFCSSNHR FGHPGGGGEQ LAINELISDG SVVYAEALWD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAAAGACAT CCTGTACTTT TGCCCCTTAG TCATCGTTTC GTCTCAAATC CAAATTTCTT 60
GAGTATACAG AAAAAAACTG CAATTTTGTC TTCACTGCTC GAGTACTTGT TGAGAACACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF00169--PH
PF00621--RhoGEF
PF00018--SH3_1

SMART

SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002073	Ailuropoda melanoleuca	64.03	0.00e+00	753.00
IUUC-Apl-004117	Anas platyrhynchos	63.83	0.00e+00	781.00
IUUC-Aca-004793	Anolis carolinensis	64.43	0.00e+00	752.00
IUUC-Ago-008003	Ashbya gossypii	28.80	9.00e-16	79.00
IUUC-Ame-010682	Astyanax mexicanus	54.47	1.00e-177	617.00
IUUC-Bgr-012058	Blumeria graminis	24.71	1.00e-15	78.60
IUUC-Bta-013253	Bos taurus	73.25	0.00e+00	863.00
IUUC-Bci-013634	Botrytis cinerea	25.68	1.00e-16	82.40
IUUC-Cja-019555	Callithrix jacchus	66.61	0.00e+00	714.00
IUUC-Cfa-020578	Canis familiaris	64.52	0.00e+00	753.00
IUUC-Cpo-021726	Cavia porcellus	34.10	3.00e-21	97.80
IUUC-Csa-023331	Chlorocebus sabaeus	72.87	0.00e+00	862.00
IUUC-Cho-025069	Choloepus hoffmanni	37.54	5.00e-56	213.00
IUUC-Cin-025453	Ciona intestinalis	44.23	2.00e-124	439.00
IUUC-Csv-025922	Ciona savignyi	45.99	1.00e-96	347.00
IUUC-Cgl-026579	Colletotrichum gloeosporioides	26.27	3.00e-14	74.30
IUUC-Cne-027023	Cryptococcus neoformans	23.32	3.00e-14	74.30
IUUC-Dre-028197	Danio rerio	83.17	0.00e+00	1046.00
IUUC-Dno-029679	Dasypus novemcinctus	66.32	0.00e+00	724.00
IUUC-Dor-030739	Dipodomys ordii	71.97	0.00e+00	858.00
IUUC-Dme-031672	Drosophila melanogaster	27.71	2.00e-23	104.00
IUUC-Ete-032545	Echinops telfairi	39.84	6.00e-47	183.00
IUUC-Eca-034299	Equus caballus	62.98	0.00e+00	741.00
IUUC-Eeu-034720	Erinaceus europaeus	37.54	1.00e-56	216.00
IUUC-Fca-036416	Felis catus	64.61	0.00e+00	690.00
IUUC-Fal-037035	Ficedula albicollis	63.34	0.00e+00	770.00
IUUC-Gmo-039587	Gadus morhua	85.97	0.00e+00	955.00
IUUC-Ggr-039728	Gaeumannomyces graminis	26.17	6.00e-13	70.10
IUUC-Gga-040841	Gallus gallus	82.97	0.00e+00	981.00
IUUC-Gac-042498	Gasterosteus aculeatus	83.42	0.00e+00	934.00
IUUC-Ggo-044700	Gorilla gorilla	37.83	4.00e-58	220.00
IUUC-Hsa-045681	Homo sapiens	67.04	0.00e+00	714.00
IUUC-Itr-048380	Ictidomys tridecemlineatus	65.43	0.00e+00	713.00
IUUC-Kpa-049278	Komagataella pastoris	29.92	3.00e-22	100.00
IUUC-Lch-049639	Latimeria chalumnae	77.86	0.00e+00	844.00
IUUC-Laf-054307	Loxodonta africana	64.52	0.00e+00	774.00
IUUC-Mcc-055305	Macaca mulatta	67.37	2.00e-148	518.00
IUUC-Meu-056376	Macropus eugenii	69.66	0.00e+00	827.00
IUUC-Mor-057139	Magnaporthe oryzae	26.67	2.00e-12	68.60
IUUC-Mpo-057433	Magnaporthe poae	25.87	8.00e-10	59.70
IUUC-Mla-059044	Melampsora laricipopulina	26.56	2.00e-22	101.00
IUUC-Mga-059644	Meleagris gallopavo	62.54	0.00e+00	761.00
IUUC-Mvi-060486	Microbotryum violaceum	28.24	2.00e-25	111.00
IUUC-Mmr-061664	Microcebus murinus	62.75	0.00e+00	717.00
IUUC-Mdo-062404	Monodelphis domestica	37.54	1.00e-57	219.00
IUUC-Mmu-063143	Mus musculus	37.83	7.00e-58	219.00
IUUC-Mpu-066851	Mustela putorius furo	66.15	0.00e+00	704.00
IUUC-Mlu-066956	Myotis lucifugus	63.55	0.00e+00	725.00
IUUC-Ncr-068819	Neurospora crassa	26.95	2.00e-10	61.20
IUUC-Nle-069174	Nomascus leucogenys	40.93	7.00e-42	164.00
IUUC-Opr-070209	Ochotona princeps	66.79	0.00e+00	708.00
IUUC-Ont-072637	Oreochromis niloticus	90.15	0.00e+00	963.00
IUUC-Oan-073722	Ornithorhynchus anatinus	62.52	0.00e+00	680.00
IUUC-Ocu-074885	Oryctolagus cuniculus	63.13	0.00e+00	713.00
IUUC-Ola-087155	Oryzias latipes	36.47	1.00e-54	209.00
IUUC-Oga-088758	Otolemur garnettii	62.64	0.00e+00	737.00
IUUC-Oar-089923	Ovis aries	75.22	0.00e+00	854.00
IUUC-Ptr-091555	Pan troglodytes	63.06	0.00e+00	760.00
IUUC-Pan-092037	Papio anubis	63.06	0.00e+00	769.00
IUUC-Psi-093865	Pelodiscus sinensis	63.99	0.00e+00	786.00
IUUC-Pfo-096918	Poecilia formosa	36.66	2.00e-55	211.00
IUUC-Pab-097910	Pongo abelii	63.23	0.00e+00	766.00
IUUC-Pca-100891	Procavia capensis	39.46	1.00e-53	205.00
IUUC-Pva-102967	Pteropus vampyrus	64.19	2.00e-166	578.00
IUUC-Pgr-103400	Puccinia graminis	27.69	2.00e-24	108.00
IUUC-Rno-105479	Rattus norvegicus	36.78	6.00e-56	213.00
IUUC-Sce-106197	Saccharomyces cerevisiae	29.96	1.00e-20	95.10
IUUC-Sha-107592	Sarcophilus harrisii	63.00	0.00e+00	751.00
IUUC-Spo-108284	Schizosaccharomyces pombe	26.06	2.00e-18	88.20
IUUC-Ssl-108541	Sclerotinia sclerotiorum	25.68	1.00e-16	82.00
IUUC-Sar-113369	Sorex araneus	67.65	3.00e-122	432.00
IUUC-Sre-115126	Sporisorium reilianum	26.48	4.00e-23	103.00
IUUC-Ssc-115967	Sus scrofa	34.10	1.00e-19	92.40
IUUC-Tgu-117088	Taeniopygia guttata	82.83	0.00e+00	1026.00
IUUC-Tru-118716	Takifugu rubripes	36.63	3.00e-56	214.00
IUUC-Tsy-118846	Tarsius syrichta	65.71	3.00e-132	464.00
IUUC-Tni-120887	Tetraodon nigroviridis	37.13	1.00e-55	212.00
IUUC-Tme-127216	Tuber melanosporum	26.16	6.00e-26	113.00
IUUC-Tbe-127248	Tupaia belangeri	39.46	2.00e-53	204.00
IUUC-Ttr-128429	Tursiops truncatus	34.56	1.00e-22	102.00
IUUC-Uma-129594	Ustilago maydis	26.09	3.00e-23	103.00
IUUC-Vda-129831	Verticillium dahliae	29.03	3.00e-11	64.30
IUUC-Vpa-130750	Vicugna pacos	39.73	4.00e-55	210.00
IUUC-Xtr-132676	Xenopus tropicalis	77.40	0.00e+00	887.00
IUUC-Xma-133871	Xiphophorus maculatus	36.66	2.00e-55	211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence