iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033750

Ensembl Protein ID

ENSECAP00000017368.1

UniProt Accession

F7E1F5; F7E1F5_HORSE

Protein Name

Uncharacterized protein

Gene Name

GRAP2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000019768.1	ENSECAT00000021105.1	ENSECAP00000017368.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.50e-29	101.2	263	314

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           ++lyd+ea +ddeL ++ G+vv+v+  ++ +  W+ g   l+++ GlfP+n+v+ +
   Q: 263  RALYDFEALEDDELGFRCGEVVEVL--DSSNPSWWTG--RLHNRLGLFPANYVAPM 314
           79***********************..999*******..8*************875 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MEAIAKFDFT ASGEDELSFH TGDVLKILSN QEEWFKAELG SQEGYVPKNF IDIQFPEWFH 60
EGLSRHQAEN LLMGKEVGFF IIRASQSSPG DFSISVRHED DVQHFKVMRD NKGNYFLWTE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACAGACTGCA GGGCAGACTG GGGGGAGTTT GGAGGAGGGA GTCAGAAGCG GGGAGGAGGA 60
CGCACGACTA ATGGAGCTGT GAGCGTGTAC CCTCTTTGAG TGTGGTACTT GGAAGACAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50001--SH2
PS50002--SH3

Pfam

PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005768--C:endosome
GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005634--C:nucleus
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0016477--P:cell migration
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway

KEGG

ecb:100055418

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001994	Ailuropoda melanoleuca	94.30	1.00e-170	592.00
IUUC-Apl-003684	Anas platyrhynchos	61.89	2.00e-105	375.00
IUUC-Aca-005371	Anolis carolinensis	56.96	6.00e-95	340.00
IUUC-Ago-007965	Ashbya gossypii	44.83	1.00e-12	67.00
IUUC-Ame-011392	Astyanax mexicanus	44.38	8.00e-69	253.00
IUUC-Bta-013508	Bos taurus	87.97	1.00e-157	548.00
IUUC-Bra-017915	Brassica rapa	30.99	1.30e+00	27.30
IUUC-Cja-019613	Callithrix jacchus	80.61	3.00e-66	243.00
IUUC-Cfa-020290	Canis familiaris	93.67	1.00e-168	585.00
IUUC-Cpo-022534	Cavia porcellus	85.32	3.00e-159	553.00
IUUC-Csa-023438	Chlorocebus sabaeus	87.58	6.00e-161	559.00
IUUC-Cho-024466	Choloepus hoffmanni	64.59	1.00e-83	302.00
IUUC-Dre-027927	Danio rerio	48.41	1.00e-76	279.00
IUUC-Dno-029894	Dasypus novemcinctus	87.96	2.00e-161	560.00
IUUC-Dor-030493	Dipodomys ordii	94.12	1.00e-83	302.00
IUUC-Ete-032335	Echinops telfairi	76.45	2.00e-131	461.00
IUUC-Eeu-034884	Erinaceus europaeus	74.68	2.00e-117	415.00
IUUC-Fca-036001	Felis catus	92.72	3.00e-168	583.00
IUUC-Fal-036692	Ficedula albicollis	60.42	9.00e-104	369.00
IUUC-Gmo-039524	Gadus morhua	62.59	1.00e-52	200.00
IUUC-Gac-041301	Gasterosteus aculeatus	60.37	2.00e-58	218.00
IUUC-Ggo-045424	Gorilla gorilla	87.58	1.00e-160	558.00
IUUC-Hsa-045808	Homo sapiens	87.88	2.00e-161	561.00
IUUC-Itr-048000	Ictidomys tridecemlineatus	86.81	4.00e-153	533.00
IUUC-Lch-049610	Latimeria chalumnae	51.57	9.00e-76	276.00
IUUC-Loc-052925	Lepisosteus oculatus	50.15	2.00e-78	285.00
IUUC-Laf-054004	Loxodonta africana	88.69	4.00e-167	580.00
IUUC-Mcc-055020	Macaca mulatta	87.88	2.00e-161	561.00
IUUC-Meu-056169	Macropus eugenii	70.03	3.00e-124	437.00
IUUC-Mga-059483	Meleagris gallopavo	60.18	6.00e-109	387.00
IUUC-Mmr-061755	Microcebus murinus	90.80	4.00e-169	587.00
IUUC-Mdo-062504	Monodelphis domestica	71.69	3.00e-130	457.00
IUUC-Mmu-063557	Mus musculus	83.49	3.00e-152	530.00
IUUC-Mpu-066852	Mustela putorius furo	93.67	1.00e-170	592.00
IUUC-Mlu-067510	Myotis lucifugus	92.77	5.00e-166	576.00
IUUC-Nle-069691	Nomascus leucogenys	87.88	2.00e-161	561.00
IUUC-Opr-070271	Ochotona princeps	85.49	8.00e-152	529.00
IUUC-Ont-072651	Oreochromis niloticus	43.90	6.00e-66	244.00
IUUC-Oan-073183	Ornithorhynchus anatinus	73.31	8.00e-124	436.00
IUUC-Ocu-074899	Oryctolagus cuniculus	80.19	2.00e-136	478.00
IUUC-Ola-086462	Oryzias latipes	46.71	6.00e-72	264.00
IUUC-Oga-088553	Otolemur garnettii	89.33	2.00e-160	558.00
IUUC-Oar-089572	Ovis aries	88.92	7.00e-160	556.00
IUUC-Ptr-090582	Pan troglodytes	88.18	1.00e-161	562.00
IUUC-Pan-092063	Papio anubis	87.88	2.00e-161	561.00
IUUC-Psi-094056	Pelodiscus sinensis	64.05	2.00e-111	395.00
IUUC-Pfo-096115	Poecilia formosa	47.45	7.00e-74	270.00
IUUC-Pab-098217	Pongo abelii	87.88	3.00e-161	560.00
IUUC-Pca-100838	Procavia capensis	87.69	5.00e-157	546.00
IUUC-Pva-102559	Pteropus vampyrus	90.00	1.00e-131	462.00
IUUC-Rno-105926	Rattus norvegicus	71.90	3.00e-128	451.00
IUUC-Sha-106948	Sarcophilus harrisii	73.67	4.00e-124	437.00
IUUC-Ssc-115605	Sus scrofa	86.88	2.00e-156	545.00
IUUC-Tgu-117211	Taeniopygia guttata	58.97	8.00e-105	373.00
IUUC-Tru-118347	Takifugu rubripes	65.99	7.00e-57	213.00
IUUC-Tsy-119441	Tarsius syrichta	87.89	3.00e-163	567.00
IUUC-Tni-119732	Tetraodon nigroviridis	45.59	2.00e-70	259.00
IUUC-Tbe-127289	Tupaia belangeri	82.45	9.00e-137	479.00
IUUC-Ttr-128961	Tursiops truncatus	90.29	7.00e-91	327.00
IUUC-Vpa-130320	Vicugna pacos	77.66	7.00e-80	289.00
IUUC-Xtr-131814	Xenopus tropicalis	48.18	1.00e-77	283.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence