iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gga-040575

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AADN04000330

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000003107.5	ENSGALT00000004906.5	ENSGALP00000004897.4

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.20e-08	35.7	320	358
UBD/Alpha-Helix/CUE	7.20e-12	45.4	435	476

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+++++   + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 320  CAICWDSMQS-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 358
           ********99.9*****************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 1    dletaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           +l+ +++q++e+FP+++y v+ ++L ++t s+e +++n+Leg 
   Q: 435  QLNAMAHQIQEMFPQVPYHVVLQDL-QLTRSVEITTDNILEGR 476
           5889*********************.***************95 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MPLLFLERFP WPSLRTYAAL SGLALLAAAL SAQRALSAAG EQRAGGPRAL DVAYYLLSDS 60
LCVWVLVNTA CCVLMLVAKL IQRVVFGPLR VSERQHLKDK FWNFIFYKFI FIFGVLNVQT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCGTTGC TGTTCCTGGA GCGCTTCCCC TGGCCCAGCC TGCGCACGTA CGCGGCGCTC 60
AGCGGCCTGG CCCTGCTGGC CGCCGCCCTC AGCGCCCAGC GCGCCCTCAG CGCGGCCGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:1990381--F:ubiquitin-specific protease binding
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0030433--P:ubiquitin-dependent ERAD pathway

KEGG

gga:415697

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000344	Aegilops tauschii	26.93	2.00e-27	116.00
IUUC-Aml-001300	Ailuropoda melanoleuca	87.16	0.00e+00	949.00
IUUC-Atr-002892	Amborella trichopoda	29.43	3.00e-35	142.00
IUUC-Apl-003404	Anas platyrhynchos	95.55	0.00e+00	1019.00
IUUC-Aca-004559	Anolis carolinensis	87.92	0.00e+00	901.00
IUUC-Aly-005440	Arabidopsis lyrata	29.77	3.00e-32	132.00
IUUC-Ath-006702	Arabidopsis thaliana	32.51	4.00e-36	145.00
IUUC-Ame-011640	Astyanax mexicanus	71.74	0.00e+00	804.00
IUUC-Bta-012980	Bos taurus	80.50	0.00e+00	1000.00
IUUC-Bdi-015070	Brachypodium distachyon	29.81	6.00e-39	155.00
IUUC-Bol-015593	Brassica oleracea	31.82	6.00e-36	145.00
IUUC-Bra-017516	Brassica rapa	32.63	2.00e-36	146.00
IUUC-Cel-018598	Caenorhabditis elegans	24.60	1.00e-34	141.00
IUUC-Cja-019577	Callithrix jacchus	84.76	0.00e+00	1040.00
IUUC-Cfa-020793	Canis familiaris	87.86	0.00e+00	961.00
IUUC-Cpo-022387	Cavia porcellus	84.76	0.00e+00	1003.00
IUUC-Cre-022743	Chlamydomonas reinhardtii	24.92	1.00e-26	113.00
IUUC-Csa-023168	Chlorocebus sabaeus	84.91	0.00e+00	1041.00
IUUC-Cho-024433	Choloepus hoffmanni	90.54	0.00e+00	805.00
IUUC-Cin-025215	Ciona intestinalis	47.81	8.00e-143	500.00
IUUC-Csv-026133	Ciona savignyi	47.43	3.00e-132	464.00
IUUC-Cme-027285	Cyanidioschyzon merolae	29.66	8.00e-23	101.00
IUUC-Dre-027594	Danio rerio	71.48	0.00e+00	758.00
IUUC-Dno-029407	Dasypus novemcinctus	89.25	0.00e+00	953.00
IUUC-Dor-030961	Dipodomys ordii	88.71	0.00e+00	971.00
IUUC-Ete-032962	Echinops telfairi	81.18	0.00e+00	807.00
IUUC-Eca-033683	Equus caballus	81.06	0.00e+00	971.00
IUUC-Eeu-034515	Erinaceus europaeus	94.81	1.00e-76	280.00
IUUC-Fca-035398	Felis catus	90.62	0.00e+00	939.00
IUUC-Fal-036758	Ficedula albicollis	86.36	0.00e+00	938.00
IUUC-Gmo-039014	Gadus morhua	68.28	0.00e+00	755.00
IUUC-Gac-041414	Gasterosteus aculeatus	68.05	0.00e+00	729.00
IUUC-Gma-044123	Glycine max	27.10	3.00e-33	136.00
IUUC-Hsa-046272	Homo sapiens	84.32	0.00e+00	1030.00
IUUC-Hvu-047279	Hordeum vulgare	31.05	2.00e-39	156.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	88.61	0.00e+00	954.00
IUUC-Lch-050491	Latimeria chalumnae	76.45	0.00e+00	862.00
IUUC-Loc-052758	Lepisosteus oculatus	74.92	0.00e+00	830.00
IUUC-Laf-053452	Loxodonta africana	88.75	0.00e+00	966.00
IUUC-Mcc-055820	Macaca mulatta	88.87	0.00e+00	963.00
IUUC-Meu-056726	Macropus eugenii	80.00	0.00e+00	781.00
IUUC-Mtr-058601	Medicago truncatula	28.21	4.00e-35	142.00
IUUC-Mga-059937	Meleagris gallopavo	98.57	0.00e+00	1049.00
IUUC-Mvi-060515	Microbotryum violaceum	26.15	2.00e-25	110.00
IUUC-Mmr-060730	Microcebus murinus	86.67	0.00e+00	1004.00
IUUC-Mdo-062771	Monodelphis domestica	89.55	0.00e+00	1003.00
IUUC-Mmu-064219	Mus musculus	85.14	0.00e+00	1030.00
IUUC-Mac-064789	Musa acuminata	28.02	7.00e-37	148.00
IUUC-Mpu-066796	Mustela putorius furo	88.14	0.00e+00	954.00
IUUC-Mlu-068189	Myotis lucifugus	86.54	0.00e+00	944.00
IUUC-Nle-069239	Nomascus leucogenys	88.77	0.00e+00	1016.00
IUUC-Opr-070702	Ochotona princeps	79.35	5.00e-128	451.00
IUUC-Ont-072033	Oreochromis niloticus	69.52	0.00e+00	798.00
IUUC-Oan-073717	Ornithorhynchus anatinus	83.53	0.00e+00	852.00
IUUC-Ocu-074145	Oryctolagus cuniculus	84.76	0.00e+00	1027.00
IUUC-Oba-075221	Oryza barthii	28.85	1.00e-36	147.00
IUUC-Obr-076914	Oryza brachyantha	29.77	2.00e-38	153.00
IUUC-Ogl-077929	Oryza glaberrima	51.16	2.00e-11	62.00
IUUC-Ogu-078124	Oryza glumaepatula	28.85	1.00e-36	147.00
IUUC-Oin-080013	Oryza indica	28.57	2.00e-35	143.00
IUUC-Olo-080247	Oryza longistaminata	28.90	6.00e-33	134.00
IUUC-Ome-081769	Oryza meridionalis	29.41	3.00e-38	152.00
IUUC-Oni-082946	Oryza nivara	28.85	1.00e-36	147.00
IUUC-Opu-083268	Oryza punctata	27.84	7.00e-26	111.00
IUUC-Oru-085114	Oryza rufipogon	28.85	1.00e-36	147.00
IUUC-Osa-085829	Oryza sativa	29.08	1.00e-37	150.00
IUUC-Ola-087152	Oryzias latipes	67.79	0.00e+00	776.00
IUUC-Oga-088486	Otolemur garnettii	89.17	0.00e+00	959.00
IUUC-Oar-089310	Ovis aries	87.86	0.00e+00	976.00
IUUC-Ptr-090649	Pan troglodytes	89.07	0.00e+00	986.00
IUUC-Pan-091692	Papio anubis	80.28	0.00e+00	963.00
IUUC-Psi-093064	Pelodiscus sinensis	96.73	0.00e+00	791.00
IUUC-Pma-094763	Petromyzon marinus	77.87	1.00e-97	348.00
IUUC-Ppa-095969	Physcomitrella patens	29.88	3.00e-38	152.00
IUUC-Pfo-096810	Poecilia formosa	68.17	0.00e+00	780.00
IUUC-Pab-097859	Pongo abelii	89.05	0.00e+00	965.00
IUUC-Pop-099245	Populus trichocarpa	27.87	8.00e-34	138.00
IUUC-Pca-100344	Procavia capensis	84.27	0.00e+00	983.00
IUUC-Ppe-101829	Prunus persica	27.78	1.00e-36	147.00
IUUC-Pva-103114	Pteropus vampyrus	60.43	6.00e-177	613.00
IUUC-Rno-105880	Rattus norvegicus	86.36	0.00e+00	976.00
IUUC-Sha-107015	Sarcophilus harrisii	90.32	0.00e+00	967.00
IUUC-Sja-107685	Schizosaccharomyces japonicus	21.68	2.00e-18	87.40
IUUC-Spo-108308	Schizosaccharomyces pombe	23.64	1.00e-20	94.40
IUUC-Smo-109664	Selaginella moellendorffii	30.72	7.00e-33	134.00
IUUC-Sit-110276	Setaria italica	29.74	8.00e-38	151.00
IUUC-Sly-111819	Solanum lycopersicum	30.21	3.00e-35	142.00
IUUC-Stu-112048	Solanum tuberosum	25.80	2.00e-31	130.00
IUUC-Sar-113397	Sorex araneus	95.42	0.00e+00	742.00
IUUC-Sbi-114192	Sorghum bicolor	29.30	1.00e-38	153.00
IUUC-Ssc-115988	Sus scrofa	80.56	3.00e-129	454.00
IUUC-Tgu-116717	Taeniopygia guttata	94.18	0.00e+00	1024.00
IUUC-Tru-117805	Takifugu rubripes	68.06	0.00e+00	813.00
IUUC-Tsy-119442	Tarsius syrichta	82.80	0.00e+00	876.00
IUUC-Tni-119777	Tetraodon nigroviridis	70.31	1.00e-176	612.00
IUUC-Tca-121462	Theobroma cacao	28.10	8.00e-35	141.00
IUUC-Tae-125239	Triticum aestivum	30.12	1.00e-40	160.00
IUUC-Tur-126538	Triticum urartu	27.30	2.00e-27	117.00
IUUC-Tbe-127322	Tupaia belangeri	65.96	1.00e-107	383.00
IUUC-Ttr-128181	Tursiops truncatus	87.81	0.00e+00	975.00
IUUC-Vpa-130483	Vicugna pacos	83.10	0.00e+00	640.00
IUUC-Vvi-130944	Vitis vinifera	28.85	3.00e-34	139.00
IUUC-Xtr-132614	Xenopus tropicalis	77.05	0.00e+00	803.00
IUUC-Xma-133943	Xiphophorus maculatus	69.19	0.00e+00	778.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence