iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049700

Ensembl Protein ID

ENSLACP00000015208.1

UniProt Accession

H3AZY7; H3AZY7_LATCH

Genbank Protein ID

ENSLACP00000015208

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01006260

Gene Name

KLHL22

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000013389.1	ENSLACT00000015314.1	ENSLACP00000015208.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.30e-18	67.3	52	116
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.10e-06	27.9	151	181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv++v +g+ ++ah+i Laas+++F+ +f ++l+e++ + +v +++v+++++  +l+F+Yt++l++
   Q: 52   DVVIVAEGKPIQAHRILLAASCDYFRGMFAGGLREMQ-QTEVLVHGVSYSAMCKILHFIYTSELEL 116
           9***********************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
           eN l+++ +Adl+++++L d+ +++ilk+F+
   Q: 151  ENLLEMYKLADLFGLTHLSDQLDSYILKNFP 181
           6889**************************6 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MAEDQDLAHP HKNAQRQQKQ PQSTCRTYRS VAHPLALLNG MVALRDSGTL FDVVIVAEGK 60
PIQAHRILLA ASCDYFRGMF AGGLREMQQT EVLVHGVSYS AMCKILHFIY TSELELSLDN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGGGCTGTT TTCAGAAGGG AACAAGAGAA GAGAACATTG CAGGTATAAG TGGGATAGTG 60
AGGCGGATGG GAATGTTTAT GTTTTAATTA AAAACAAAAT CTACTTTGTT TTCATTTTTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030575--KLHL22
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0051301--P:cell division
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002097	Ailuropoda melanoleuca	60.38	0.00e+00	754.00
IUUC-Apl-004081	Anas platyrhynchos	63.03	0.00e+00	805.00
IUUC-Aca-005015	Anolis carolinensis	56.87	0.00e+00	688.00
IUUC-Ame-011712	Astyanax mexicanus	52.13	0.00e+00	650.00
IUUC-Bta-012594	Bos taurus	59.75	0.00e+00	757.00
IUUC-Cja-019752	Callithrix jacchus	58.43	7.00e-171	593.00
IUUC-Cfa-020884	Canis familiaris	60.53	0.00e+00	770.00
IUUC-Cpo-021711	Cavia porcellus	60.97	0.00e+00	776.00
IUUC-Csa-023211	Chlorocebus sabaeus	60.34	0.00e+00	764.00
IUUC-Dre-028395	Danio rerio	54.95	0.00e+00	683.00
IUUC-Dno-030096	Dasypus novemcinctus	60.94	0.00e+00	784.00
IUUC-Dor-030709	Dipodomys ordii	67.92	9.00e-148	516.00
IUUC-Eca-033388	Equus caballus	60.97	0.00e+00	773.00
IUUC-Eeu-034616	Erinaceus europaeus	52.83	0.00e+00	648.00
IUUC-Fca-035815	Felis catus	60.38	0.00e+00	769.00
IUUC-Fal-037311	Ficedula albicollis	63.25	0.00e+00	756.00
IUUC-Gmo-039571	Gadus morhua	60.10	4.00e-141	494.00
IUUC-Gga-040992	Gallus gallus	63.18	0.00e+00	807.00
IUUC-Gac-042041	Gasterosteus aculeatus	51.40	4.00e-175	607.00
IUUC-Ggo-045141	Gorilla gorilla	56.09	0.00e+00	702.00
IUUC-Hsa-045984	Homo sapiens	60.62	0.00e+00	767.00
IUUC-Itr-048890	Ictidomys tridecemlineatus	60.66	0.00e+00	769.00
IUUC-Loc-052141	Lepisosteus oculatus	56.06	0.00e+00	713.00
IUUC-Laf-053487	Loxodonta africana	61.22	0.00e+00	768.00
IUUC-Mcc-054682	Macaca mulatta	57.71	0.00e+00	636.00
IUUC-Meu-055937	Macropus eugenii	54.22	0.00e+00	676.00
IUUC-Mga-059953	Meleagris gallopavo	63.18	0.00e+00	807.00
IUUC-Mmr-061743	Microcebus murinus	60.47	0.00e+00	767.00
IUUC-Mdo-062328	Monodelphis domestica	60.28	0.00e+00	771.00
IUUC-Mmu-063979	Mus musculus	61.73	0.00e+00	773.00
IUUC-Mpu-066750	Mustela putorius furo	60.69	0.00e+00	772.00
IUUC-Mlu-066960	Myotis lucifugus	60.00	0.00e+00	766.00
IUUC-Nle-069690	Nomascus leucogenys	60.85	0.00e+00	684.00
IUUC-Opr-071059	Ochotona princeps	55.97	0.00e+00	697.00
IUUC-Ont-072004	Oreochromis niloticus	53.48	2.00e-175	608.00
IUUC-Oan-073172	Ornithorhynchus anatinus	49.92	1.00e-159	556.00
IUUC-Ola-086599	Oryzias latipes	51.57	5.00e-180	624.00
IUUC-Oga-087980	Otolemur garnettii	61.06	0.00e+00	773.00
IUUC-Oar-089956	Ovis aries	58.37	0.00e+00	662.00
IUUC-Ptr-090598	Pan troglodytes	60.99	0.00e+00	688.00
IUUC-Pan-092387	Papio anubis	57.71	0.00e+00	636.00
IUUC-Psi-093484	Pelodiscus sinensis	62.50	0.00e+00	794.00
IUUC-Pma-094224	Petromyzon marinus	46.38	4.00e-150	524.00
IUUC-Pfo-096149	Poecilia formosa	50.32	0.00e+00	632.00
IUUC-Pab-098097	Pongo abelii	60.34	0.00e+00	766.00
IUUC-Pca-100118	Procavia capensis	68.19	1.00e-149	523.00
IUUC-Rno-105350	Rattus norvegicus	62.90	0.00e+00	763.00
IUUC-Sha-106817	Sarcophilus harrisii	49.25	1.00e-68	254.00
IUUC-Sar-113490	Sorex araneus	69.68	8.00e-143	500.00
IUUC-Ssc-115827	Sus scrofa	59.91	0.00e+00	763.00
IUUC-Tgu-116748	Taeniopygia guttata	64.20	0.00e+00	691.00
IUUC-Tru-118644	Takifugu rubripes	51.07	0.00e+00	631.00
IUUC-Tsy-118888	Tarsius syrichta	55.61	1.00e-173	602.00
IUUC-Tni-120060	Tetraodon nigroviridis	48.01	1.00e-148	519.00
IUUC-Ttr-129183	Tursiops truncatus	60.43	0.00e+00	684.00
IUUC-Uma-129534	Ustilago maydis	37.84	4.00e-01	31.60
IUUC-Xtr-132780	Xenopus tropicalis	60.00	0.00e+00	745.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence