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Tag Content
UUCD2 ID IUUC-Fca-036288
UUCD1 version UUC-FeC-00769
Ensembl Protein ID ENSFCAP00000008955.3
UniProt Accession M3WBU7; M3WBU7_FELCA
Genbank Protein ID ENSFCAP00000008955
Protein Name Ubiquitinyl hydrolase 1
Genbank Nucleotide ID AANG02144697
Gene Name USP44
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSFCAG00000009656.3 ENSFCAT00000009657.3 ENSFCAP00000008955.3
Status Unreviewed
Classification
Family E-Value Score Start End
DUB/USP 7.70e-97 324.5 272 676
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   DUB/USP
   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle...........kkkeklneenp.................................... 42
           tGl+NlgNtCYmNSvLQ+Ls++  +r+++l+           ++        +                                    
   Q: 272  TGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKldlnrwlavtaSD--------Ktrspykhppvtdtvyqmnecqekdtgcvpsrhpsls 352
           7******************************8887666554422........1334455558888888888888888899999999999 PP
   S: 43   .....................kepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkke 110
                                +++  +l+++l++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ lld+++ el   
   Q: 353  lglsggasksrkmeliqpkepSSQYISLCHELHTLFQVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQHEL--- 438
           99999998888888888776666666************************************************************... PP
   S: 111  knkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.......slqdcLe 192
                 e+++++  +l   +++k  k+  ++++++F+gql sq++c +cdn+s++ epf+dlsl++p++ +++ +        ++++L+
   Q: 439  ------ETTGTRLPALIPTSQRKLIKQVLNVVNNIFHGQLLSQVTCVACDNKSNTIEPFWDLSLEFPERYQCSGKdiasqpcLVTEMLA 521
           ......7788888999999************************************************9998877788888889****** PP
   S: 193  sftkeeelegenkyycekckkkqe...........aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspee 270
           +ft++e leg+  y c++c++k++           a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c++++ 
   Q: 522  KFTETEALEGKI-YVCDQCNSKRRrfssksvvlteARKQLMVCHLPQVLRLHLKRFRWSGR-NNREKIGVHVGFEEILNMEPYCCRESL 608
           *********965.*******999999999999999***********************998.7778********************998 PP
   S: 271  kqke..kkkYeLiavvvHsG.slssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkr 337
           k+ +  + +Y+L+avv+H+G +++sGHY+ay++n++g+ W++++Dsk + ++++ev++   ++aY+lfY++
   Q: 609  KSLRpeCFIYDLSAVVMHHGkGFGSGHYTAYCYNSEGGfWVHCNDSKLSMCTMDEVCK---AQAYILFYTQ 676
           8876779***************************9999********************...********98 PP
   
Organism Felis catus
Protein Sequence
(Fasta)
MLTMDKCKHI GQLRLAQDHS ILNPQKWHCV DCNTTESIWA CLSCSHVACG RYIEEHAVRH 60
FQDSSHPVAL EVNEMYVFCY LCDDYVLNDN ATGDLKLLRS TLSAIKSQNY QCTTRSGRVL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Fca-036288|DUB,USP|Felis catus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGTGAAAGT TGGAGGGGCT TCTACTTAGG AGATAAACAT CTGCGCAGAT TTAAAGGTGG 60
GAAGTGCCTG AAGTGTGCAA GACTGTAAAG AGACTGACCT CCTAGCAGTC AAAGGCCGAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Fca-036288|DUB,USP|Felis catus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP
PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP
Pfam

PF00443--UCH
PF02148--zf-UBP
SMART

SM00290--ZnF_UBP
Gene Ontology

GO:0005634--C:nucleus
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008270--F:zinc ion binding
GO:1904667--P:negative regulation of ubiquitin protein ligase activity
GO:0016579--P:protein deubiquitination
GO:0090231--P:regulation of spindle checkpoint
GO:0006511--P:ubiquitin-dependent protein catabolic process
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001220 Ailuropoda melanoleuca 96.20 0.00e+00 1399.00
IUUC-Apl-003673 Anas platyrhynchos 74.75 0.00e+00 1051.00
IUUC-Aca-004434 Anolis carolinensis 71.51 0.00e+00 1036.00
IUUC-Ame-010986 Astyanax mexicanus 68.76 3.00e-180 625.00
IUUC-Bta-012774 Bos taurus 90.44 0.00e+00 1302.00
IUUC-Cja-019619 Callithrix jacchus 89.90 0.00e+00 1288.00
IUUC-Cfa-020957 Canis familiaris 94.94 0.00e+00 1397.00
IUUC-Csa-023177 Chlorocebus sabaeus 90.18 0.00e+00 1294.00
IUUC-Cho-024877 Choloepus hoffmanni 89.92 0.00e+00 857.00
IUUC-Cin-025587 Ciona intestinalis 48.17 2.00e-107 383.00
IUUC-Csv-025814 Ciona savignyi 45.45 1.00e-154 540.00
IUUC-Dre-027878 Danio rerio 72.60 3.00e-178 618.00
IUUC-Dno-029832 Dasypus novemcinctus 91.84 0.00e+00 1339.00
IUUC-Ete-032627 Echinops telfairi 86.68 0.00e+00 1254.00
IUUC-Eca-033863 Equus caballus 86.04 0.00e+00 1237.00
IUUC-Eeu-035225 Erinaceus europaeus 85.96 0.00e+00 1221.00
IUUC-Fal-037207 Ficedula albicollis 73.76 0.00e+00 1014.00
IUUC-Gga-040457 Gallus gallus 74.23 0.00e+00 1014.00
IUUC-Gac-042595 Gasterosteus aculeatus 53.22 0.00e+00 697.00
IUUC-Ggo-044926 Gorilla gorilla 90.32 0.00e+00 1286.00
IUUC-Hsa-046079 Homo sapiens 89.76 0.00e+00 1282.00
IUUC-Itr-048737 Ictidomys tridecemlineatus 91.01 0.00e+00 1301.00
IUUC-Lch-050260 Latimeria chalumnae 67.56 0.00e+00 932.00
IUUC-Loc-051981 Lepisosteus oculatus 76.51 0.00e+00 672.00
IUUC-Laf-054491 Loxodonta africana 89.11 0.00e+00 1226.00
IUUC-Mcc-055694 Macaca mulatta 90.04 0.00e+00 1288.00
IUUC-Mga-059523 Meleagris gallopavo 74.05 0.00e+00 1036.00
IUUC-Mmr-060885 Microcebus murinus 92.57 0.00e+00 1320.00
IUUC-Mdo-063018 Monodelphis domestica 79.04 0.00e+00 1117.00
IUUC-Mmu-064012 Mus musculus 79.07 0.00e+00 1085.00
IUUC-Mpu-066207 Mustela putorius furo 94.23 0.00e+00 1398.00
IUUC-Mlu-066929 Myotis lucifugus 88.70 0.00e+00 1217.00
IUUC-Nle-069313 Nomascus leucogenys 80.44 0.00e+00 1115.00
IUUC-Opr-070375 Ochotona princeps 81.09 0.00e+00 1117.00
IUUC-Ont-071637 Oreochromis niloticus 68.06 2.00e-176 612.00
IUUC-Oan-073030 Ornithorhynchus anatinus 77.28 0.00e+00 841.00
IUUC-Ocu-074836 Oryctolagus cuniculus 87.61 0.00e+00 1241.00
IUUC-Ola-086413 Oryzias latipes 54.55 2.00e-163 568.00
IUUC-Oga-088367 Otolemur garnettii 92.57 0.00e+00 1303.00
IUUC-Oar-089953 Ovis aries 92.42 0.00e+00 1350.00
IUUC-Ptr-090980 Pan troglodytes 90.18 0.00e+00 1289.00
IUUC-Pan-092748 Papio anubis 90.73 0.00e+00 1303.00
IUUC-Psi-093353 Pelodiscus sinensis 61.97 0.00e+00 847.00
IUUC-Pma-094155 Petromyzon marinus 71.71 1.00e-80 292.00
IUUC-Pfo-096413 Poecilia formosa 54.40 0.00e+00 723.00
IUUC-Pab-098514 Pongo abelii 90.46 0.00e+00 1294.00
IUUC-Pca-100449 Procavia capensis 59.21 0.00e+00 793.00
IUUC-Pva-102984 Pteropus vampyrus 91.84 0.00e+00 1296.00
IUUC-Rno-106019 Rattus norvegicus 80.00 0.00e+00 1140.00
IUUC-Sha-106965 Sarcophilus harrisii 77.81 0.00e+00 1113.00
IUUC-Ssc-115299 Sus scrofa 93.11 0.00e+00 1367.00
IUUC-Tgu-117160 Taeniopygia guttata 74.27 0.00e+00 1018.00
IUUC-Tru-118156 Takifugu rubripes 60.91 0.00e+00 835.00
IUUC-Tsy-118814 Tarsius syrichta 58.56 0.00e+00 783.00
IUUC-Tni-119733 Tetraodon nigroviridis 60.83 0.00e+00 842.00
IUUC-Tbe-128084 Tupaia belangeri 85.96 0.00e+00 1245.00
IUUC-Ttr-128928 Tursiops truncatus 94.37 0.00e+00 1368.00
IUUC-Vpa-130706 Vicugna pacos 93.39 0.00e+00 1352.00
IUUC-Xtr-132061 Xenopus tropicalis 71.49 0.00e+00 939.00
Created Date 25-Jun-2017

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