iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-091445

UUCD1 version

UUC-PaT-01103

Ensembl Protein ID

ENSPTRP00000032292.3

UniProt Accession

H2QU57; H2QU57_PANTR

Genbank Protein ID

JAA04793.1; JAA30960.1

Protein Name

Ubiquitin specific peptidase 42

Genbank Nucleotide ID

AC183919; GABD01002140

Gene Name

USP42

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000018906.3	ENSPTRT00000034939.3	ENSPTRP00000032292.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-81	273.8	112	411

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeq 89
           Gl+NlgNtC+ N++LQcL+ +p+l++++l+ ++++++++     +  ++++++q  +++ +++   +++p  +++ ++++a++f+  +q
   Q: 112  GLQNLGNTCFANAALQCLTYTPPLANYMLShEHSKTCHA-----EGFCMMCTMQAHITQALSNPGDVIKPMFVINEMRRIARHFRFGNQ 195
           9*****************************445555544.....578****************************************** PP
   S: 90   qDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpg 178
           +Da+Efl++ +d++++++                  l+ +++ + +++ ++l+ ++F+g l+s++kcl+c+ vs +++p ld++l+++ 
   Q: 196  EDAHEFLQYTVDAMQKAC------------------LNGSNKLDRHTQATTLVCQIFGGYLRSRVKCLNCKGVSDTFDPYLDITLEIKA 266
           ******************..................3344567789999**************************************** PP
   S: 179  keetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfcts 267
            +     s++++Le+f+k+e+l+gen y+c+kckk + a+k++++++ ++vL+l LkRf    ++    ki k v++p+ Ld++p++++
   Q: 267  AQ-----SVNKALEQFVKPEQLDGENSYKCSKCKKMVPASKRFTIHRSSNVLTLSLKRF----ANFTGGKIAKDVKYPEYLDIRPYMSQ 346
           **.....9***************************************************....668889******************** PP
   S: 268  peekqkekkkYeLiavvvHsG.slssGHYvayvknekgkWllfdDskVtevkeeevleetgstaYvlfYkr 337
           p+ +   +  Y L+av+vH+G +++ GHY++y+k ++g W++++Ds V++++  +vl+   ++aYvlfY r
   Q: 347  PNGE---PIVYVLYAVLVHTGfNCHAGHYFCYIKASNGLWYQMNDSIVSTSDIRSVLS---QQAYVLFYIR 411
           9977...8**************************************************...********87 PP

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MTIVDKASES SDPSAYQNQP GSSEAVSPGD MDAGSASWGA VSSLNDVSNH TLSLGPVPGA 60
VVYSSSSVPD KSKPSPQKDQ ALGDGIAPPQ KVLFPSEKIC LKWQQTHRVG AGLQNLGNTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGGCGGCGG TGCCCGGATG GAGGCACGTC ATTGTCCCCC GCCGGGCGGC TGGGCTGTGT 60
GCGGCGGCGG CGGCGGCGGC GGCGGCCGAG GGGGATGGAG CGAGCGCCGA GCCGGGTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000401	Aegilops tauschii	39.21	4.00e-71	263.00
IUUC-Aml-002303	Ailuropoda melanoleuca	73.91	0.00e+00	1404.00
IUUC-Atr-003102	Amborella trichopoda	46.91	1.00e-85	311.00
IUUC-Apl-003459	Anas platyrhynchos	55.42	0.00e+00	728.00
IUUC-Aca-004440	Anolis carolinensis	68.78	0.00e+00	955.00
IUUC-Aly-006389	Arabidopsis lyrata	42.36	1.00e-76	280.00
IUUC-Ath-006710	Arabidopsis thaliana	42.36	2.00e-76	280.00
IUUC-Ago-007836	Ashbya gossypii	26.44	1.00e-34	141.00
IUUC-Ame-011358	Astyanax mexicanus	67.92	0.00e+00	672.00
IUUC-Bta-012803	Bos taurus	72.44	0.00e+00	1593.00
IUUC-Bol-015996	Brassica oleracea	39.13	4.00e-82	299.00
IUUC-Bra-016634	Brassica rapa	43.31	2.00e-82	300.00
IUUC-Cja-019199	Callithrix jacchus	91.45	0.00e+00	2048.00
IUUC-Cfa-020597	Canis familiaris	76.59	0.00e+00	1664.00
IUUC-Cpo-021945	Cavia porcellus	70.73	0.00e+00	1577.00
IUUC-Csa-023485	Chlorocebus sabaeus	96.50	0.00e+00	2123.00
IUUC-Cho-024575	Choloepus hoffmanni	76.24	0.00e+00	986.00
IUUC-Dre-028442	Danio rerio	64.59	0.00e+00	658.00
IUUC-Dno-029673	Dasypus novemcinctus	75.02	0.00e+00	1759.00
IUUC-Dor-030518	Dipodomys ordii	63.62	3.00e-131	462.00
IUUC-Ete-033088	Echinops telfairi	58.75	0.00e+00	948.00
IUUC-Eca-033579	Equus caballus	74.89	0.00e+00	1656.00
IUUC-Eeu-034511	Erinaceus europaeus	54.50	0.00e+00	934.00
IUUC-Fca-035792	Felis catus	74.55	0.00e+00	1540.00
IUUC-Fal-037075	Ficedula albicollis	54.94	0.00e+00	758.00
IUUC-Gga-040504	Gallus gallus	53.76	0.00e+00	730.00
IUUC-Gma-044075	Glycine max	47.88	4.00e-85	309.00
IUUC-Ggo-044798	Gorilla gorilla	95.38	0.00e+00	1930.00
IUUC-Hsa-046072	Homo sapiens	98.71	0.00e+00	2136.00
IUUC-Hvu-047620	Hordeum vulgare	41.25	3.00e-74	273.00
IUUC-Itr-048078	Ictidomys tridecemlineatus	77.40	0.00e+00	1825.00
IUUC-Lch-049867	Latimeria chalumnae	67.91	0.00e+00	951.00
IUUC-Loc-052621	Lepisosteus oculatus	63.97	0.00e+00	699.00
IUUC-Laf-054330	Loxodonta africana	92.77	0.00e+00	1301.00
IUUC-Mcc-054900	Macaca mulatta	99.75	0.00e+00	801.00
IUUC-Mga-059501	Meleagris gallopavo	41.04	0.00e+00	724.00
IUUC-Mvi-060547	Microbotryum violaceum	45.62	1.00e-80	294.00
IUUC-Mmr-060864	Microcebus murinus	75.86	0.00e+00	1782.00
IUUC-Mdo-062395	Monodelphis domestica	60.92	0.00e+00	1443.00
IUUC-Mmu-064236	Mus musculus	68.78	0.00e+00	1500.00
IUUC-Mpu-065822	Mustela putorius furo	77.50	0.00e+00	1734.00
IUUC-Mlu-067091	Myotis lucifugus	72.97	0.00e+00	1584.00
IUUC-Nle-069004	Nomascus leucogenys	96.88	0.00e+00	2152.00
IUUC-Opr-071170	Ochotona princeps	63.33	0.00e+00	1142.00
IUUC-Ont-071832	Oreochromis niloticus	61.58	0.00e+00	650.00
IUUC-Oan-073711	Ornithorhynchus anatinus	57.46	0.00e+00	1255.00
IUUC-Ocu-074596	Oryctolagus cuniculus	96.82	0.00e+00	1055.00
IUUC-Oga-088641	Otolemur garnettii	75.34	0.00e+00	1710.00
IUUC-Oar-089760	Ovis aries	68.96	0.00e+00	1496.00
IUUC-Pan-092484	Papio anubis	96.50	0.00e+00	2045.00
IUUC-Psi-093277	Pelodiscus sinensis	54.10	0.00e+00	1098.00
IUUC-Pma-094651	Petromyzon marinus	37.93	2.00e-56	212.00
IUUC-Pfo-096469	Poecilia formosa	66.73	0.00e+00	656.00
IUUC-Pab-097794	Pongo abelii	97.17	0.00e+00	1981.00
IUUC-Ppe-101678	Prunus persica	46.25	2.00e-82	300.00
IUUC-Pva-103238	Pteropus vampyrus	69.44	0.00e+00	1458.00
IUUC-Rno-105068	Rattus norvegicus	69.27	0.00e+00	1508.00
IUUC-Sha-106713	Sarcophilus harrisii	62.24	0.00e+00	1475.00
IUUC-Smo-108763	Selaginella moellendorffii	48.05	9.00e-81	293.00
IUUC-Sit-109895	Setaria italica	44.30	2.00e-83	304.00
IUUC-Sar-113340	Sorex araneus	66.74	0.00e+00	1352.00
IUUC-Tgu-117149	Taeniopygia guttata	44.85	0.00e+00	839.00
IUUC-Tru-117776	Takifugu rubripes	64.88	4.00e-175	608.00
IUUC-Tsy-118974	Tarsius syrichta	76.08	0.00e+00	1746.00
IUUC-Tni-120774	Tetraodon nigroviridis	68.00	5.00e-173	600.00
IUUC-Tbe-128006	Tupaia belangeri	66.82	7.00e-126	445.00
IUUC-Ttr-128764	Tursiops truncatus	64.63	0.00e+00	1352.00
IUUC-Vvi-131535	Vitis vinifera	46.35	5.00e-87	315.00
IUUC-Xtr-132544	Xenopus tropicalis	57.46	0.00e+00	648.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence