iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-096561

Ensembl Protein ID

ENSPFOP00000029163.1

UniProt Accession

A0A096MCM2; A0A096MCM2_POEFO

Genbank Protein ID

ENSPFOP00000029163

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01010885

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000016583.2	ENSPFOT00000027161.1	ENSPFOP00000029163.1
ENSPFOG00000016583.2	ENSPFOT00000016719.2	ENSPFOP00000016697.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.70e-104	347.8	733	1568

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsg 86
           tGl+NlgNtC+mNS +Qc sn+++l +++l+ ++  +ln+ np ++ g+++k++ +l+ elw++++k+++p +l  +++k+a++f+g
   Q: 733  TGLSNLGNTCFMNSSIQCVSNTKPLSDYFLSgRHLYELNRINPIGMRGHMAKCYGDLVLELWSGTQKSIAPLKLRWTIAKYAPRFNG 819
           7******************************99****************************************************** PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreep 168
           ++qqD+qE+laflld+l+e+l++ ++kp+ e++++d   ++d+     a++++ ++n+s+++dlF+gqlksq+kc++c+++s r++p
   Q: 820  FQQQDSQELLAFLLDGLHEDLNRVHEKPYVELKDSD--GRPDWevaseAWDNHLRRNRSIVVDLFHGQLKSQVKCKTCGHISARFDP 904
           ********************************9999..5555566777*************************************** PP
   S: 169  fldlslpvpgkeetkke...................................................................... 185
           f+ lslp+p+++++++e                                                                      
   Q: 905  FNFLSLPLPMDSSMHLEitvikldgstpvryglrlnmdekytglkkllselcslkpeqillaevhasniknfpqdnqkvrlsvngfl 991
           ************99999********************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 992  cafevpvpgsptslssptltgyspvaadfsrtgglhvqpditptaanghliangglgtllpstpetplvngvanghisplqdspfig 1078
           *************************************************************************************** PP
   S: 186  ....................................................................................... 185
                                                                                                  
   Q: 1079 yiiamhrkmmrtelyflssqknrpslfgmplivpctvhtskkdlydavwiqvsrlasplppqeasnhaqdcddsmgyqypftlrvvg 1165
           *************************************************************************************** PP
   S: 186  ........................................................................slqdcLesftkeeel 200
                                                                                   sl++cL++ft+eeel
   Q: 1166 kdgnscawcpwyrfcrgctiectedrasvgnayiavdwdptalhlryqtsqeriveehcsveqsrraqaepiSLDSCLKAFTSEEEL 1252
           *************************************************************************************** PP
   S: 201  egenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ldlspfcts................... 267
            +++ yyc+kck ++ a+kkl+l++lP++Li+hLkRf+f +   + +k +k v+fp+e +d s f++                    
   Q: 1253 GEDELYYCSKCKTHRLATKKLDLWRLPPILIVHLKRFQFVNG--RWIKSQKIVKFPQEsFDPSAFLAPrdlehrslhsrsesedllr 1337
           *************************************99775..5569********************7777777777777777777 PP
   S: 268  ....................................................................peekqke............ 274
                                                                               +     +            
   Q: 1338 eilsldsqstplsavlstivshlftlnitspassrrsapslsrnsspsgspkpaghrpgrlrlpqlssK-----Hrlssskenldga 1419
           776666666666666666666666666666666666666666666655555555555555555555550.....0555555555666 PP
   S: 275  ......................................................................................k 275
                                                                                                 +
   Q: 1420 asseadsrdgapqadteervaiaagagpvgysdqaasesscsreasssycdvilmngdsngmgsdcsiesnvdpdssllqhrdmclD 1506
           6666666666666666677777777777777777777778888888888888888999999999999999999999999999**99* PP
   S: 276  kkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVt..evkeeevleetgstaYvlfYkrr 338
             Y+L+a+ +HsG +++GHYv+y+kn ++kW++++Ds+ +  ev+ ee+ +   ++aY+lfY+++
   Q: 1507 PLYNLYAISCHSGIMGGGHYVTYAKNPNDKWYCYNDSSLEghEVHSEEIDT---DSAYILFYEQQ 1568
           *************************************99833566789999...********985 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MGAKESRIGF LSYDEAVKRV TDVELKRLKD AFKRTSGLSC YMTQQCFYRE VLGDGVPPKV 60
AEVIYSSFGG SSKGLHFNNL IVGLVLLTRG RDEEKAKYLF SLFASDLSGY AAREDIEAVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATCACTTCGT TCCTGTTTAC AGACGTTGAT CAACTGACCT GTAGAGTGAG ATCATGTGAC 60
ATAGCATAGA GGCGTCGCTG AAAACATTCA CCCGTTCACC ACATAGACAC ACCGCCAGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0106--Calcium
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF13202--EF-hand_5
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP
SM00054--EFh

Gene Ontology

GO:0005509--F:calcium ion binding
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001611	Ailuropoda melanoleuca	72.90	0.00e+00	1971.00
IUUC-Apl-003272	Anas platyrhynchos	72.68	0.00e+00	2285.00
IUUC-Aca-005057	Anolis carolinensis	79.50	0.00e+00	2061.00
IUUC-Ame-010781	Astyanax mexicanus	79.32	0.00e+00	2534.00
IUUC-Bta-013502	Bos taurus	70.87	0.00e+00	2128.00
IUUC-Cja-018754	Callithrix jacchus	74.28	0.00e+00	2358.00
IUUC-Cfa-020526	Canis familiaris	73.42	0.00e+00	2320.00
IUUC-Cpo-021568	Cavia porcellus	70.76	0.00e+00	2118.00
IUUC-Csa-023143	Chlorocebus sabaeus	74.55	0.00e+00	2338.00
IUUC-Cho-024603	Choloepus hoffmanni	90.64	2.00e-111	398.00
IUUC-Cin-025583	Ciona intestinalis	49.19	0.00e+00	1251.00
IUUC-Csv-026344	Ciona savignyi	43.20	0.00e+00	1275.00
IUUC-Dre-028121	Danio rerio	79.42	0.00e+00	2492.00
IUUC-Dno-029911	Dasypus novemcinctus	73.23	0.00e+00	2281.00
IUUC-Dor-030608	Dipodomys ordii	57.45	7.00e-164	572.00
IUUC-Dme-032094	Drosophila melanogaster	45.26	3.00e-121	430.00
IUUC-Ete-032639	Echinops telfairi	69.81	0.00e+00	1175.00
IUUC-Eca-034253	Equus caballus	74.24	0.00e+00	2312.00
IUUC-Eeu-035084	Erinaceus europaeus	66.47	0.00e+00	1306.00
IUUC-Fca-035474	Felis catus	71.52	0.00e+00	1870.00
IUUC-Fal-036985	Ficedula albicollis	73.36	0.00e+00	2299.00
IUUC-Gmo-039568	Gadus morhua	82.21	0.00e+00	2571.00
IUUC-Gga-040509	Gallus gallus	73.92	0.00e+00	2406.00
IUUC-Gac-041757	Gasterosteus aculeatus	84.66	0.00e+00	2708.00
IUUC-Ggo-044956	Gorilla gorilla	75.80	0.00e+00	1517.00
IUUC-Hsa-046107	Homo sapiens	74.66	0.00e+00	2360.00
IUUC-Itr-048865	Ictidomys tridecemlineatus	65.41	0.00e+00	793.00
IUUC-Lch-050681	Latimeria chalumnae	71.34	0.00e+00	2178.00
IUUC-Loc-052474	Lepisosteus oculatus	77.32	0.00e+00	2468.00
IUUC-Laf-054273	Loxodonta africana	74.23	0.00e+00	2347.00
IUUC-Mcc-054718	Macaca mulatta	74.43	0.00e+00	2355.00
IUUC-Meu-056558	Macropus eugenii	62.64	0.00e+00	1217.00
IUUC-Mga-059892	Meleagris gallopavo	74.12	0.00e+00	2304.00
IUUC-Mmr-060866	Microcebus murinus	74.18	0.00e+00	2374.00
IUUC-Mdo-062607	Monodelphis domestica	75.69	0.00e+00	2420.00
IUUC-Mmu-063797	Mus musculus	74.23	0.00e+00	2396.00
IUUC-Mpu-066121	Mustela putorius furo	73.91	0.00e+00	2371.00
IUUC-Mlu-067581	Myotis lucifugus	73.70	0.00e+00	2367.00
IUUC-Nle-069916	Nomascus leucogenys	72.70	0.00e+00	2251.00
IUUC-Opr-071073	Ochotona princeps	68.03	0.00e+00	945.00
IUUC-Ont-071310	Oreochromis niloticus	92.11	0.00e+00	2482.00
IUUC-Oan-073356	Ornithorhynchus anatinus	73.73	0.00e+00	2353.00
IUUC-Ocu-074216	Oryctolagus cuniculus	74.54	0.00e+00	2354.00
IUUC-Ola-087434	Oryzias latipes	84.91	0.00e+00	2601.00
IUUC-Oga-089034	Otolemur garnettii	73.05	0.00e+00	2278.00
IUUC-Oar-090369	Ovis aries	74.70	0.00e+00	2325.00
IUUC-Ptr-090605	Pan troglodytes	74.54	0.00e+00	2359.00
IUUC-Pan-092381	Papio anubis	74.01	0.00e+00	2281.00
IUUC-Psi-093819	Pelodiscus sinensis	74.46	0.00e+00	2353.00
IUUC-Pma-094480	Petromyzon marinus	62.61	0.00e+00	1436.00
IUUC-Pab-097643	Pongo abelii	72.02	0.00e+00	2252.00
IUUC-Pca-100944	Procavia capensis	66.19	0.00e+00	815.00
IUUC-Pva-102732	Pteropus vampyrus	66.36	0.00e+00	2040.00
IUUC-Rno-105113	Rattus norvegicus	74.00	0.00e+00	2336.00
IUUC-Sar-113201	Sorex araneus	69.24	0.00e+00	1088.00
IUUC-Tgu-117322	Taeniopygia guttata	74.46	0.00e+00	2398.00
IUUC-Tru-118705	Takifugu rubripes	79.18	0.00e+00	695.00
IUUC-Tsy-119433	Tarsius syrichta	66.89	0.00e+00	1137.00
IUUC-Tni-120631	Tetraodon nigroviridis	82.01	0.00e+00	2537.00
IUUC-Tbe-127553	Tupaia belangeri	75.32	8.00e-169	588.00
IUUC-Ttr-128260	Tursiops truncatus	73.53	0.00e+00	2323.00
IUUC-Vpa-130479	Vicugna pacos	69.65	0.00e+00	2146.00
IUUC-Xtr-132686	Xenopus tropicalis	72.83	0.00e+00	2303.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence