iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ssc-115727

Ensembl Protein ID

ENSSSCP00000026764.1

UniProt Accession

I3LRM6; I3LRM6_PIG

Genbank Protein ID

ENSSSCP00000026764

Protein Name

Ubiquitinyl hydrolase 1

Genbank Nucleotide ID

CU468691

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000027775.1	ENSSSCT00000023974.1	ENSSSCP00000026764.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-98	330.7	242	626

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenp....................................kepkgellksl 53
           tGl+NlgNtCYmNS+LQ+Ls+++++re++l+ +++k+++  p                                    ++++ +l+++l
   Q: 242  TGLRNLGNTCYMNSILQVLSHLRKFRECFLNLDPSKTEQLFPraangkapltgrlasssanggaslsrsleliqnkepSSKHISLCHEL 330
           7******************************7777777777777778888999999999999999999999999998889999****** PP
   S: 54   qklfeelwkskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknksli 142
           ++lf+ +w++k+  vsp ++l++++++ + f+gy+qqDaqEfl+ ll+++++el         e+e+++++ l   +++k +k+  +++
   Q: 331  HTLFRVMWSGKWALVSPFAMLHSVWSLIPAFRGYDQQDAQEFLCELLHKVQQEL---------ESEGTTRRILIPFSQRKLTKQVLKVV 410
           ******************************************************.........6688888999999************* PP
   S: 143  sdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke..........slqdcLesftkeeelegenkyycekckkkqe..... 216
           +++F+gql sq++c +c+ +s++ epf+dlsl++p++ ++ ++           l+++L++ft++e leg+  y c++c++k++     
   Q: 411  NTIFHGQLLSQVTCISCNYKSNTIEPFWDLSLEFPERYHCIEKgfvplnqtecLLTEMLAKFTETEALEGRI-YACDQCNSKRRksnpk 498
           **************************************998879*************************965.*******9999999** PP
   S: 217  ......aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke..kkkYeLiavvvHsG.slssGHYv 296
                 a+k+l++ +lP+vL lhLkRf++s + ++reki  +v f + L+++p+c+++  ++ +  +  Y+L+avv+H+G +++sGHY+
   Q: 499  xlvlseARKQLMIYRLPQVLRLHLKRFRWSGR-NHREKIGVHVVFDQVLTMEPYCCRDMLSSLDkeTFAYDLSAVVMHHGkGFGSGHYT 586
           *****************************997.8889********************876654433999******************** PP
   S: 297  ayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYkrr 338
           ay++n++g+ W++++Dsk ++++ eev++   ++aY+lfY++r
   Q: 587  AYCYNTEGGfWVHCNDSKLNVCSVEEVCK---TQAYILFYTQR 626
           *****9999********************...********985 PP

Organism

Sus scrofa

Protein Sequence
(Fasta)

MDRCKHVGRL RLAQDHSILN PQKWCCRECA TTESVWACLK CSHVACGRYI EDHALKHFEE 60
TGHPLAMEVR DLYVFCYLCK DYVLNDNPEG DLKLLRSSLL AVRGQTQDLP LRRGRTLRSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATAGAT GCAAACATGT AGGGCGGTTG CGGCTCGCCC AGGACCATTC CATCCTGAAC 60
CCTCAGAAGT GGTGCTGCCG GGAGTGCGCC ACCACCGAGT CCGTGTGGGC TTGTCTCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Dre-027577	Danio rerio	60.90	0.00e+00	722.00
IUUC-Gac-042595	Gasterosteus aculeatus	60.38	0.00e+00	760.00
IUUC-Meu-055971	Macropus eugenii	67.84	3.00e-148	518.00
IUUC-Ont-072103	Oreochromis niloticus	60.35	0.00e+00	767.00
IUUC-Pfo-096413	Poecilia formosa	61.01	0.00e+00	771.00
IUUC-Tru-117585	Takifugu rubripes	61.81	0.00e+00	767.00
IUUC-Tni-120600	Tetraodon nigroviridis	61.80	0.00e+00	737.00
IUUC-Tme-126976	Tuber melanosporum	32.12	9.00e-42	164.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence