iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afu-009022

Ensembl Protein ID

CADAFUAP00007922

UniProt Accession

Q4WPX3; Q4WPX3_ASPFU

Genbank Protein ID

EAL89711.1

Protein Name

Ubiquitin-protein ligase (Tom1), putative

Genbank Nucleotide ID

AAHF01000005

Gene Name

AFUA_4G10780

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
CADAFUAG00007922	CADAFUAT00007922	CADAFUAP00007922

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.00e-118	395.6	3704	4035

Active Site

Position(s)	Description	Evidence
4004	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 4    dlkk.rlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlpls 93
           +lk+ +l+v+f gEeg+d+gGvtre+++ l++ ++np++ lf   + d++t++pn+ sg+ n ehl +F+f+Gr++gkal++gr+ld+++s
   Q: 3704 ELKYgKLNVRFHGEEGVDAGGVTREWFQVLARGMFNPNYALFIPVAADRTTFHPNRLSGV-NSEHLMFFKFIGRIIGKALYEGRVLDCHFS 3793
           66755899***************************************************9.56**************************** PP
   S: 94   ksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlke 184
           +++yk++lg+++s++d+e++d ++yksl +++en   di+++ ++ tf v+++ +ge ++ +L+++G+nipVt+eNkeeYv++vv+yrl +
   Q: 3794 RAVYKCILGRSVSIKDMETLDLDYYKSLLWMLEN---DITDI-ITETFAVETDDFGEKQVIDLIENGRNIPVTQENKEEYVQRVVDYRLVK 3880
           ********************************99...99999.999********************************************* PP
   S: 185  gikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlP 275
           ++k q+++f +Gf+++ip++l+s+F+e+elelli+G +eidv+d+k++t+y++ y+++sp+iqwFw+++++f++eer+++LqFvTg+s++P
   Q: 3881 SVKDQLDNFLKGFHDIIPPDLISIFNEQELELLISGLPEIDVDDWKANTEYHN-YSASSPQIQWFWRAVRSFDKEERAKLLQFVTGTSKVP 3970
           ***************************************************66.************************************* PP
   S: 276  lgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFe 334
           l+Gf+el+     ++f i++ ++++drlPss+TCfn+L+LPeY+s+e+l+++L +A++ + + F+
   Q: 3971 LNGFKELEgmngVSKFNIHRdYGNKDRLPSSHTCFNQLDLPEYDSYETLRQRLYTAMTAGsDYFG 4035
           ********99997778888878889*******************************998866665 PP

Organism

Aspergillus fumigatus

Protein Sequence
(Fasta)

MGRIKKVASQ KHEATISPYL TEFVARATTV SVPELPLHLN TFSRLWPFPR GDLYHWINVL 60
NRFDDILTSV IEKYALNAGP QTKPFGRYVL IDAYTSSDGQ SSSEDADFRL NALGYGPEGD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAGAA TCAAGAAGGT GGCCAGCCAA AAGCATGAGG CGACAATTGT AAGTCATTAA 60
CCCCGCTCGA TCTCTAGCTC AGGAATGCAG GCTGACTGAA AATTTTCTCT CCTGTTTCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

afm:AFUA_4G10780

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000627	Aegilops tauschii	31.52	3.00e-123	436.00
IUUC-Aml-001684	Ailuropoda melanoleuca	53.19	3.00e-133	469.00
IUUC-Atr-003044	Amborella trichopoda	42.12	8.00e-139	488.00
IUUC-Apl-003729	Anas platyrhynchos	51.83	2.00e-100	356.00
IUUC-Aca-005263	Anolis carolinensis	53.66	3.00e-134	473.00
IUUC-Aly-006157	Arabidopsis lyrata	40.96	1.00e-138	487.00
IUUC-Ath-007472	Arabidopsis thaliana	43.27	1.00e-135	477.00
IUUC-Ago-008005	Ashbya gossypii	57.70	0.00e+00	751.00
IUUC-Acl-008254	Aspergillus clavatus	84.03	0.00e+00	3921.00
IUUC-Afl-008712	Aspergillus flavus	86.51	0.00e+00	1837.00
IUUC-Ani-009412	Aspergillus nidulans	71.56	0.00e+00	3711.00
IUUC-Ang-009771	Aspergillus niger	79.44	0.00e+00	5971.00
IUUC-Aor-010186	Aspergillus oryzae	83.73	0.00e+00	2125.00
IUUC-Ate-010253	Aspergillus terreus	74.67	0.00e+00	3438.00
IUUC-Ame-011067	Astyanax mexicanus	52.94	3.00e-132	466.00
IUUC-Bgr-012043	Blumeria graminis	40.41	0.00e+00	1499.00
IUUC-Bta-012813	Bos taurus	53.19	5.00e-133	469.00
IUUC-Bci-013995	Botrytis cinerea	59.37	0.00e+00	1233.00
IUUC-Bdi-014884	Brachypodium distachyon	34.74	2.00e-135	477.00
IUUC-Bol-016533	Brassica oleracea	55.64	4.00e-92	328.00
IUUC-Bra-016726	Brassica rapa	43.06	4.00e-139	489.00
IUUC-Cel-018179	Caenorhabditis elegans	51.53	1.00e-129	457.00
IUUC-Cja-018741	Callithrix jacchus	53.19	2.00e-132	466.00
IUUC-Cfa-020083	Canis familiaris	53.19	3.00e-133	469.00
IUUC-Cpo-021766	Cavia porcellus	42.66	6.00e-97	347.00
IUUC-Cre-022900	Chlamydomonas reinhardtii	52.25	2.00e-132	463.00
IUUC-Csa-023853	Chlorocebus sabaeus	53.19	4.00e-133	469.00
IUUC-Cho-024718	Choloepus hoffmanni	55.71	2.00e-121	430.00
IUUC-Cin-025627	Ciona intestinalis	52.25	3.00e-131	463.00
IUUC-Csv-025872	Ciona savignyi	52.01	5.00e-128	449.00
IUUC-Cgl-026647	Colletotrichum gloeosporioides	36.28	0.00e+00	1200.00
IUUC-Cne-027095	Cryptococcus neoformans	41.48	0.00e+00	639.00
IUUC-Cme-027267	Cyanidioschyzon merolae	51.07	2.00e-119	422.00
IUUC-Dre-028525	Danio rerio	52.44	1.00e-120	428.00
IUUC-Dno-029680	Dasypus novemcinctus	53.19	5.00e-133	469.00
IUUC-Dor-030902	Dipodomys ordii	47.99	1.00e-112	401.00
IUUC-Dse-031197	Dothistroma septosporum	36.59	0.00e+00	1326.00
IUUC-Dme-032122	Drosophila melanogaster	52.94	6.00e-130	459.00
IUUC-Ete-032966	Echinops telfairi	42.66	5.00e-97	347.00
IUUC-Eca-033915	Equus caballus	52.13	1.00e-130	461.00
IUUC-Eeu-034963	Erinaceus europaeus	52.83	6.00e-131	462.00
IUUC-Fca-035824	Felis catus	53.19	3.00e-133	469.00
IUUC-Fox-037756	Fusarium oxysporum	57.11	0.00e+00	1234.00
IUUC-Fso-038464	Fusarium solani	36.27	0.00e+00	1193.00
IUUC-Gmo-039073	Gadus morhua	52.96	3.00e-133	469.00
IUUC-Ggr-039946	Gaeumannomyces graminis	70.96	0.00e+00	964.00
IUUC-Gga-040309	Gallus gallus	57.65	2.00e-105	373.00
IUUC-Gac-042430	Gasterosteus aculeatus	52.96	4.00e-133	469.00
IUUC-Gma-044216	Glycine max	33.16	4.00e-154	539.00
IUUC-Ggo-044465	Gorilla gorilla	42.43	4.00e-96	344.00
IUUC-Hsa-046879	Homo sapiens	53.19	4.00e-133	469.00
IUUC-Hvu-047697	Hordeum vulgare	40.91	4.00e-134	473.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	53.19	2.00e-133	469.00
IUUC-Kpa-049228	Komagataella pastoris	59.62	0.00e+00	774.00
IUUC-Lch-050252	Latimeria chalumnae	53.07	2.00e-132	466.00
IUUC-Lpe-051550	Leersia perrieri	40.29	5.00e-136	479.00
IUUC-Loc-052472	Lepisosteus oculatus	53.43	4.00e-134	473.00
IUUC-Lma-053159	Leptosphaeria maculans	41.55	0.00e+00	1626.00
IUUC-Laf-054154	Loxodonta africana	53.19	4.00e-133	469.00
IUUC-Mcc-055085	Macaca mulatta	53.19	3.00e-133	469.00
IUUC-Mor-057201	Magnaporthe oryzae	34.60	0.00e+00	1177.00
IUUC-Mpo-057597	Magnaporthe poae	70.87	0.00e+00	959.00
IUUC-Mtr-057633	Medicago truncatula	32.99	7.00e-155	541.00
IUUC-Mla-058888	Melampsora laricipopulina	58.97	3.00e-145	506.00
IUUC-Mga-059935	Meleagris gallopavo	42.66	2.00e-96	345.00
IUUC-Mvi-060320	Microbotryum violaceum	44.15	0.00e+00	741.00
IUUC-Mmr-060820	Microcebus murinus	53.19	3.00e-133	469.00
IUUC-Mdo-062930	Monodelphis domestica	53.43	1.00e-133	471.00
IUUC-Mmu-063601	Mus musculus	53.19	4.00e-133	469.00
IUUC-Mac-065229	Musa acuminata	34.35	7.00e-154	538.00
IUUC-Mpu-066653	Mustela putorius furo	53.19	5.00e-133	469.00
IUUC-Mlu-067418	Myotis lucifugus	53.19	3.00e-133	469.00
IUUC-Nfi-068278	Neosartorya fischeri	97.45	0.00e+00	7147.00
IUUC-Ncr-068813	Neurospora crassa	35.39	0.00e+00	1166.00
IUUC-Nle-069418	Nomascus leucogenys	53.19	5.00e-133	469.00
IUUC-Ont-071300	Oreochromis niloticus	52.96	4.00e-133	469.00
IUUC-Oan-073046	Ornithorhynchus anatinus	53.41	6.00e-133	469.00
IUUC-Ocu-074178	Oryctolagus cuniculus	53.19	2.00e-133	470.00
IUUC-Oba-075757	Oryza barthii	39.94	6.00e-139	488.00
IUUC-Obr-076553	Oryza brachyantha	41.67	1.00e-138	488.00
IUUC-Ogl-077520	Oryza glaberrima	39.94	8.00e-139	488.00
IUUC-Ogu-078278	Oryza glumaepatula	39.94	7.00e-139	488.00
IUUC-Oin-079767	Oryza indica	39.94	5.00e-139	488.00
IUUC-Olo-080380	Oryza longistaminata	39.71	4.00e-137	482.00
IUUC-Ome-081925	Oryza meridionalis	39.71	3.00e-137	483.00
IUUC-Oni-082619	Oryza nivara	39.94	5.00e-139	488.00
IUUC-Opu-083684	Oryza punctata	39.71	4.00e-137	482.00
IUUC-Oru-084501	Oryza rufipogon	39.94	5.00e-139	488.00
IUUC-Osa-086251	Oryza sativa	39.94	2.00e-138	484.00
IUUC-Ola-086777	Oryzias latipes	42.89	2.00e-98	352.00
IUUC-Olu-087813	Ostreococcus lucimarinus	47.67	4.00e-115	405.00
IUUC-Oga-088903	Otolemur garnettii	53.19	4.00e-133	469.00
IUUC-Oar-090210	Ovis aries	53.19	4.00e-133	469.00
IUUC-Ptr-090529	Pan troglodytes	42.66	1.00e-96	345.00
IUUC-Pan-092368	Papio anubis	52.96	5.00e-121	429.00
IUUC-Pno-094871	Phaeosphaeria nodorum	41.29	0.00e+00	1622.00
IUUC-Ppa-095657	Physcomitrella patens	45.82	1.00e-130	461.00
IUUC-Pfo-096232	Poecilia formosa	52.96	3.00e-133	469.00
IUUC-Pab-098583	Pongo abelii	53.19	4.00e-133	469.00
IUUC-Pop-099468	Populus trichocarpa	40.36	1.00e-139	491.00
IUUC-Ppe-101641	Prunus persica	45.51	3.00e-137	483.00
IUUC-Pva-102116	Pteropus vampyrus	50.12	1.00e-119	424.00
IUUC-Pgr-103465	Puccinia graminis	49.18	0.00e+00	641.00
IUUC-Ptt-103813	Puccinia triticina	41.13	0.00e+00	757.00
IUUC-Pte-104018	Pyrenophora teres	42.51	0.00e+00	1717.00
IUUC-Pyt-104713	Pyrenophora triticirepentis	41.88	0.00e+00	1687.00
IUUC-Rno-105153	Rattus norvegicus	42.66	5.00e-97	347.00
IUUC-Sce-106449	Saccharomyces cerevisiae	55.85	0.00e+00	729.00
IUUC-Sha-106961	Sarcophilus harrisii	46.08	7.00e-134	472.00
IUUC-Sja-107814	Schizosaccharomyces japonicus	45.83	0.00e+00	891.00
IUUC-Spo-108024	Schizosaccharomyces pombe	46.86	0.00e+00	839.00
IUUC-Smo-109640	Selaginella moellendorffii	50.80	1.00e-134	474.00
IUUC-Sit-110598	Setaria italica	43.90	2.00e-139	489.00
IUUC-Sly-111706	Solanum lycopersicum	43.41	1.00e-139	490.00
IUUC-Stu-112894	Solanum tuberosum	34.71	7.00e-57	213.00
IUUC-Sar-113291	Sorex araneus	53.12	1.00e-128	454.00
IUUC-Sbi-114042	Sorghum bicolor	33.89	5.00e-147	515.00
IUUC-Sre-114958	Sporisorium reilianum	58.74	7.00e-175	605.00
IUUC-Ssc-115754	Sus scrofa	53.19	4.00e-133	469.00
IUUC-Tru-118570	Takifugu rubripes	52.96	3.00e-133	469.00
IUUC-Tni-120836	Tetraodon nigroviridis	51.30	3.00e-127	449.00
IUUC-Tca-121479	Theobroma cacao	32.22	2.00e-151	530.00
IUUC-Tre-121909	Trichoderma reesei	58.09	0.00e+00	1189.00
IUUC-Tvi-122370	Trichoderma virens	57.98	0.00e+00	1196.00
IUUC-Tae-125214	Triticum aestivum	31.85	4.00e-143	501.00
IUUC-Tur-126774	Triticum urartu	32.45	1.00e-51	196.00
IUUC-Tme-127172	Tuber melanosporum	73.62	0.00e+00	991.00
IUUC-Ttr-129253	Tursiops truncatus	53.19	6.00e-133	468.00
IUUC-Uma-129355	Ustilago maydis	57.76	3.00e-179	619.00
IUUC-Vda-129886	Verticillium dahliae	56.71	0.00e+00	1177.00
IUUC-Vpa-130708	Vicugna pacos	53.19	1.00e-132	468.00
IUUC-Vvi-131078	Vitis vinifera	43.92	9.00e-138	484.00
IUUC-Xtr-132123	Xenopus tropicalis	51.87	8.00e-127	448.00
IUUC-Xma-133869	Xiphophorus maculatus	52.96	1.00e-133	471.00
IUUC-Yli-134657	Yarrowia lipolytica	62.01	0.00e+00	828.00
IUUC-Zma-135570	Zea mays	43.22	7.00e-139	488.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence