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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105924
Ensembl Protein ID ENSRNOP00000056281.3
UniProt Accession F1M0N1; F1M0N1_RAT
Genbank Protein ID EDM09480.1
Protein Name Tyrosine-protein kinase
Genbank Nucleotide ID AABR07021474
Gene Name Abl2; Abl2_mapped; rCG_46463
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000004305.5 ENSRNOT00000059524.3 ENSRNOP00000056281.3
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
TRANSFACRAID2
Protein-protein Interaction
IIDHINT
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.80e-12 46.8 107 164
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 3    kekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            +++ +lyd+ a+ d++L+++kG++++v+  ++q+++W +     ++ +G +P+n+++ ++
   Q: 107  PNLFVALYDFVASGDNTLSITKGEKLRVL-GYNQNGEWSEV--RSKNGQGWVPSNYITPVN 164
           67899************************.*********98..788899*********997 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MGQQVGRVGE APGLQQPQPR GIRGSSAARP SGRRRDPVGR TADAGFNVFT QHGQGDCRTV 60
DGIPRKGRMK AEVLHRPFGC DAESQALNEA IRWSSKENLL GATESDPNLF VALYDFVASG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105924|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGGCAGC AGGTGGGCCG CGTCGGGGAG GCTCCCGGGC TCCAGCAGCC ACAGCCGCGC 60
GGGATCCGGG GCAGCAGCGC AGCCAGGCCC TCCGGCCGCA GGCGGGACCC GGTGGGGCGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105924|UBD,SH3|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase
Interpro

IPR015015--F-actin_binding
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom
PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3
Pfam

PF08919--F_actin_bind
PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00401--SH2DOMAIN
PR00109--TYRKINASE
SMART

SM00808--FABD
SM00252--SH2
SM00326--SH3
SM00219--TyrKc
Gene Ontology

GO:0031234--C:extrinsic component of cytoplasmic side of plasma membrane
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0030145--F:manganese ion binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity
GO:0005102--F:receptor binding
GO:0030154--P:cell differentiation
GO:0071300--P:cellular response to retinoic acid
GO:0045087--P:innate immune response
GO:0038083--P:peptidyl-tyrosine autophosphorylation
GO:0007204--P:positive regulation of cytosolic calcium ion concentration
GO:0010976--P:positive regulation of neuron projection development
GO:0051353--P:positive regulation of oxidoreductase activity
GO:0010863--P:positive regulation of phospholipase C activity
GO:0042127--P:regulation of cell proliferation
GO:0007169--P:transmembrane receptor protein tyrosine kinase signaling pathway
KEGG rno:304883
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002263 Ailuropoda melanoleuca 92.43 0.00e+00 1898.00
IUUC-Apl-003389 Anas platyrhynchos 85.06 0.00e+00 1686.00
IUUC-Ame-010629 Astyanax mexicanus 57.99 0.00e+00 1040.00
IUUC-Bta-013370 Bos taurus 90.69 0.00e+00 1954.00
IUUC-Cja-018894 Callithrix jacchus 90.96 0.00e+00 1902.00
IUUC-Cfa-020398 Canis familiaris 95.81 0.00e+00 1191.00
IUUC-Cpo-022367 Cavia porcellus 94.29 0.00e+00 1467.00
IUUC-Csa-023386 Chlorocebus sabaeus 92.61 0.00e+00 1895.00
IUUC-Cho-024714 Choloepus hoffmanni 93.66 0.00e+00 1368.00
IUUC-Dre-027741 Danio rerio 66.72 0.00e+00 1364.00
IUUC-Dno-029246 Dasypus novemcinctus 89.66 0.00e+00 1927.00
IUUC-Dor-030416 Dipodomys ordii 85.86 0.00e+00 1751.00
IUUC-Ete-032899 Echinops telfairi 71.91 0.00e+00 792.00
IUUC-Eca-033387 Equus caballus 92.11 0.00e+00 1852.00
IUUC-Eeu-035058 Erinaceus europaeus 81.49 0.00e+00 1773.00
IUUC-Fca-036578 Felis catus 85.57 0.00e+00 1708.00
IUUC-Fal-037491 Ficedula albicollis 85.77 0.00e+00 1806.00
IUUC-Gmo-038509 Gadus morhua 77.42 0.00e+00 1113.00
IUUC-Gga-040638 Gallus gallus 83.70 0.00e+00 1764.00
IUUC-Gac-042550 Gasterosteus aculeatus 67.24 0.00e+00 1290.00
IUUC-Ggo-044487 Gorilla gorilla 91.29 0.00e+00 1941.00
IUUC-Hsa-046636 Homo sapiens 91.29 0.00e+00 1941.00
IUUC-Itr-048685 Ictidomys tridecemlineatus 92.56 0.00e+00 1891.00
IUUC-Lch-049530 Latimeria chalumnae 73.76 0.00e+00 1545.00
IUUC-Loc-051933 Lepisosteus oculatus 70.27 0.00e+00 1414.00
IUUC-Laf-053802 Loxodonta africana 90.37 0.00e+00 1994.00
IUUC-Mcc-054836 Macaca mulatta 91.12 0.00e+00 1943.00
IUUC-Mga-059277 Meleagris gallopavo 85.57 0.00e+00 1771.00
IUUC-Mmr-061206 Microcebus murinus 89.68 0.00e+00 1928.00
IUUC-Mdo-062281 Monodelphis domestica 93.43 0.00e+00 1214.00
IUUC-Mmu-063847 Mus musculus 94.33 0.00e+00 1981.00
IUUC-Mpu-066309 Mustela putorius furo 93.30 0.00e+00 1280.00
IUUC-Mlu-068070 Myotis lucifugus 92.06 0.00e+00 1887.00
IUUC-Nle-070062 Nomascus leucogenys 93.45 0.00e+00 1236.00
IUUC-Opr-070534 Ochotona princeps 88.66 0.00e+00 997.00
IUUC-Ont-072440 Oreochromis niloticus 68.06 0.00e+00 1240.00
IUUC-Oan-073526 Ornithorhynchus anatinus 86.87 0.00e+00 1533.00
IUUC-Ocu-074051 Oryctolagus cuniculus 91.17 0.00e+00 1786.00
IUUC-Ola-086752 Oryzias latipes 95.04 0.00e+00 908.00
IUUC-Oga-088767 Otolemur garnettii 85.34 0.00e+00 1694.00
IUUC-Oar-089800 Ovis aries 92.06 0.00e+00 1899.00
IUUC-Ptr-090857 Pan troglodytes 93.45 0.00e+00 1235.00
IUUC-Pan-092279 Papio anubis 91.02 0.00e+00 1926.00
IUUC-Psi-093573 Pelodiscus sinensis 86.43 0.00e+00 1748.00
IUUC-Pfo-096543 Poecilia formosa 71.49 0.00e+00 1144.00
IUUC-Pab-097949 Pongo abelii 90.17 0.00e+00 1900.00
IUUC-Pca-100370 Procavia capensis 89.33 0.00e+00 1368.00
IUUC-Pva-103220 Pteropus vampyrus 80.73 0.00e+00 1653.00
IUUC-Sha-107114 Sarcophilus harrisii 84.82 0.00e+00 1350.00
IUUC-Ssc-115968 Sus scrofa 91.57 0.00e+00 1980.00
IUUC-Tgu-117301 Taeniopygia guttata 85.59 0.00e+00 1731.00
IUUC-Tru-118410 Takifugu rubripes 65.70 0.00e+00 1364.00
IUUC-Tni-119991 Tetraodon nigroviridis 65.65 0.00e+00 1363.00
IUUC-Tbe-127362 Tupaia belangeri 86.46 0.00e+00 1770.00
IUUC-Ttr-129291 Tursiops truncatus 91.88 0.00e+00 1876.00
IUUC-Vpa-130800 Vicugna pacos 93.03 0.00e+00 1470.00
IUUC-Xtr-132965 Xenopus tropicalis 71.43 0.00e+00 1274.00
Created Date 25-Jun-2017

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