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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063099
UUCD1 version UUC-MuM-00213
Ensembl Protein ID ENSMUSP00000043389.6
UniProt Accession Q6PFY8; E9Q2K9; Q3U5H4; Q8BVT5; TRI45_MOUSE
Genbank Protein ID BAE29669.1; BAE32104.1; BAC36409.1; CAM22066.1; AAH57358.1
Protein Name Tripartite motif-containing protein 45
Genbank Nucleotide ID AK150574; AK153571; AK076600; AL669872; BC057358
Gene Name Trim45
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000033233.17 ENSMUST00000094048.9 ENSMUSP00000091590.3
ENSMUSG00000033233.17 ENSMUST00000037409.12 ENSMUSP00000043389.6
ENSMUSG00000033233.17 ENSMUST00000134993.2 ENSMUSP00000115669.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlus
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/RING 4.40e-07 31.4 29 97
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/RING
   S: 1    CaiCledfkdgplvlpCgHvfhadClqkw.........................pglknssskefrCPlC 45
           C++Cl  fk  p++lpC H+ +++Cl+k+                          + + + +  ++CP+C
   Q: 29   CPTCLRLFKV-PRLLPCLHTVCTTCLEKLdpfsvvdirggdsdtssegsvfqdpELCSLQPQIGILCPVC 97
           ******9988.******************9999999988877777777777666555555566667***9 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     No experimental confirmation available. Ref.1 (BAC36409) sequence is in conflict in position: 534:R->S. Ref.1 (BAC36409) sequence is in conflict in position: 535:P->T.
 No experimental confirmation available. Ref.1 (BAC36409) sequence is in conflict in position: 534:R->S. Ref.1 (BAC36409) sequence is in conflict in position: 535:P->T.
Protein Sequence
(Fasta)
MSEIRKPLLG FVHKLQDANA SGSSGKTHCP TCLRLFKVPR LLPCLHTVCT TCLEKLDPFS 60
VVDIRGGDSD TSSEGSVFQD PELCSLQPQI GILCPVCDAQ VDLPLGGVKA LTVDHLAMND 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063099|E3,RING|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCACATTACG CCGCTCACTC CCAGACTCCT CCTCCCGGTT CTGCACGAGG CCCTCCCTTG 60
CTCCCTCTCC TTTCGCCGCG CGAGTGGCCG GCGAGGATGT GGACCTTGCT GAACTTATTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063099|E3,RING|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR003649--Bbox_C
IPR017868--Filamin/ABP280_repeat-like
IPR001298--Filamin/ABP280_rpt
IPR013783--Ig-like_fold
IPR014756--Ig_E-set
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
PROSITE

PS50194--FILAMIN_REPEAT
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2
Pfam

PF00630--Filamin
PF00643--zf-B_box
PF13445--zf-RING_UBOX
SMART

SM00502--BBC
SM00336--BBOX
SM00557--IG_FLMN
SM00184--RING
Gene Ontology

GO:0005829--C:cytosol
GO:0045171--C:intercellular bridge
GO:0005654--C:nucleoplasm
GO:0008270--F:zinc ion binding
GO:0060348--P:bone development
KEGG mmu:229644
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002020 Ailuropoda melanoleuca 86.38 0.00e+00 974.00
IUUC-Ani-009267 Aspergillus nidulans 32.61 5.50e-01 30.00
IUUC-Ame-010865 Astyanax mexicanus 47.22 3.00e-126 445.00
IUUC-Bta-012744 Bos taurus 85.00 0.00e+00 963.00
IUUC-Cel-018225 Caenorhabditis elegans 23.80 5.00e-20 93.60
IUUC-Cja-019162 Callithrix jacchus 83.62 0.00e+00 944.00
IUUC-Cfa-020163 Canis familiaris 86.55 0.00e+00 974.00
IUUC-Csa-023746 Chlorocebus sabaeus 86.38 0.00e+00 973.00
IUUC-Cho-024414 Choloepus hoffmanni 74.39 0.00e+00 725.00
IUUC-Dre-028598 Danio rerio 48.92 1.00e-117 417.00
IUUC-Dno-029616 Dasypus novemcinctus 84.85 0.00e+00 958.00
IUUC-Dor-030216 Dipodomys ordii 81.44 2.00e-67 249.00
IUUC-Dme-031817 Drosophila melanogaster 30.45 3.00e-64 240.00
IUUC-Ete-032434 Echinops telfairi 82.71 0.00e+00 871.00
IUUC-Eca-034410 Equus caballus 85.34 0.00e+00 974.00
IUUC-Eeu-034954 Erinaceus europaeus 84.34 0.00e+00 955.00
IUUC-Fca-035410 Felis catus 85.52 0.00e+00 963.00
IUUC-Gmo-039232 Gadus morhua 47.87 4.00e-130 458.00
IUUC-Gac-042350 Gasterosteus aculeatus 45.36 1.00e-105 377.00
IUUC-Ggo-045080 Gorilla gorilla 86.55 0.00e+00 974.00
IUUC-Hsa-046580 Homo sapiens 86.03 0.00e+00 968.00
IUUC-Itr-048145 Ictidomys tridecemlineatus 84.31 0.00e+00 949.00
IUUC-Lch-049464 Latimeria chalumnae 57.50 0.00e+00 639.00
IUUC-Loc-052772 Lepisosteus oculatus 51.16 8.00e-69 254.00
IUUC-Mcc-055349 Macaca mulatta 84.66 0.00e+00 945.00
IUUC-Meu-056674 Macropus eugenii 64.48 0.00e+00 724.00
IUUC-Mmr-061225 Microcebus murinus 85.15 0.00e+00 958.00
IUUC-Mdo-062597 Monodelphis domestica 62.00 0.00e+00 675.00
IUUC-Mlu-067034 Myotis lucifugus 84.14 0.00e+00 943.00
IUUC-Nle-069855 Nomascus leucogenys 86.55 0.00e+00 1004.00
IUUC-Opr-070954 Ochotona princeps 84.75 0.00e+00 946.00
IUUC-Ont-071292 Oreochromis niloticus 48.76 4.00e-128 451.00
IUUC-Oga-087909 Otolemur garnettii 83.10 0.00e+00 946.00
IUUC-Oar-089619 Ovis aries 84.83 0.00e+00 959.00
IUUC-Ptr-090712 Pan troglodytes 85.69 0.00e+00 963.00
IUUC-Pan-092806 Papio anubis 86.21 0.00e+00 974.00
IUUC-Psi-093414 Pelodiscus sinensis 64.81 0.00e+00 712.00
IUUC-Pfo-096848 Poecilia formosa 47.32 9.00e-129 454.00
IUUC-Pab-098353 Pongo abelii 84.66 0.00e+00 968.00
IUUC-Pca-100183 Procavia capensis 83.13 0.00e+00 941.00
IUUC-Pva-102140 Pteropus vampyrus 82.76 0.00e+00 947.00
IUUC-Rno-105886 Rattus norvegicus 92.93 0.00e+00 1043.00
IUUC-Sha-107458 Sarcophilus harrisii 64.89 0.00e+00 693.00
IUUC-Sar-112944 Sorex araneus 65.34 0.00e+00 654.00
IUUC-Sbi-114481 Sorghum bicolor 36.36 4.00e-05 43.50
IUUC-Ssc-116231 Sus scrofa 84.66 0.00e+00 958.00
IUUC-Tgu-116859 Taeniopygia guttata 55.88 6.00e-153 533.00
IUUC-Tru-118209 Takifugu rubripes 47.19 1.00e-128 453.00
IUUC-Tni-120290 Tetraodon nigroviridis 48.25 3.00e-116 412.00
IUUC-Tbe-128111 Tupaia belangeri 86.50 0.00e+00 855.00
IUUC-Ttr-128584 Tursiops truncatus 83.28 0.00e+00 895.00
IUUC-Vvi-131620 Vitis vinifera 31.00 2.00e-05 42.00
IUUC-Xtr-132137 Xenopus tropicalis 44.75 1.00e-107 383.00
IUUC-Xma-134298 Xiphophorus maculatus 47.03 5.00e-130 457.00
Created Date 25-Jun-2017

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