iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-020687

Ensembl Protein ID

ENSCAFP00000010712.2

UniProt Accession

E2QUS6; E2QUS6_CANLF

Genbank Protein ID

ENSCAFP00000010712

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03014274

Gene Name

LATS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000007207.3	ENSCAFT00000011560.2	ENSCAFP00000010712.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/UBA	85.41	0.00e+00	1841.00	IUUC-Hsa-046254

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Canis familiaris

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KSSAQGLPVG PNSDASLATK VLGGKDAARQ 60
QQQMRATPKF GPYQKALREI RYSLLPFANE SGTSAAAEVN RQMLQELVNA GCDQEMAGRA 120

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Nucleotide Sequence
(Fasta)

ATGGTGATGA TCTTCAAAAT GAAGACTCTG GAAAATTTTG GGTTCTCTAT AGGAACTACA 60
AAAATTGAAG GAAAGAAAAT TTTCAAAAGG AAATTGTTTT GAAAGTATGT TTACAACTAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR017892--Pkinase_C
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase
PF00433--Pkinase_C

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0001827--P:inner cell mass cell fate commitment
GO:0001828--P:inner cell mass cellular morphogenesis
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0018105--P:peptidyl-serine phosphorylation
GO:0043065--P:positive regulation of apoptotic process
GO:0046620--P:regulation of organ growth

KEGG

cfa:477343

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	95.94	0.00e+00	2161.00
IUUC-Apl-003521	Anas platyrhynchos	74.32	0.00e+00	1291.00
IUUC-Aca-004995	Anolis carolinensis	72.88	0.00e+00	1561.00
IUUC-Ame-011481	Astyanax mexicanus	62.39	0.00e+00	1243.00
IUUC-Bta-012618	Bos taurus	74.16	0.00e+00	1009.00
IUUC-Cja-019430	Callithrix jacchus	84.63	0.00e+00	1793.00
IUUC-Cpo-021985	Cavia porcellus	87.58	0.00e+00	1089.00
IUUC-Csa-023534	Chlorocebus sabaeus	97.31	0.00e+00	1011.00
IUUC-Cho-024363	Choloepus hoffmanni	80.49	0.00e+00	739.00
IUUC-Dre-027538	Danio rerio	61.90	0.00e+00	1262.00
IUUC-Dno-029126	Dasypus novemcinctus	85.65	0.00e+00	1937.00
IUUC-Dor-030172	Dipodomys ordii	81.54	0.00e+00	1546.00
IUUC-Eca-033868	Equus caballus	91.55	0.00e+00	2007.00
IUUC-Eeu-034881	Erinaceus europaeus	69.22	0.00e+00	1373.00
IUUC-Fca-036203	Felis catus	87.10	0.00e+00	1852.00
IUUC-Fal-036668	Ficedula albicollis	76.24	0.00e+00	1694.00
IUUC-Gmo-039195	Gadus morhua	85.28	0.00e+00	783.00
IUUC-Gac-041789	Gasterosteus aculeatus	61.89	0.00e+00	1178.00
IUUC-Ggo-044904	Gorilla gorilla	81.93	0.00e+00	1716.00
IUUC-Hsa-046254	Homo sapiens	85.20	0.00e+00	1729.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	83.69	0.00e+00	1583.00
IUUC-Lch-050079	Latimeria chalumnae	68.50	0.00e+00	1508.00
IUUC-Loc-052265	Lepisosteus oculatus	69.00	0.00e+00	926.00
IUUC-Laf-053806	Loxodonta africana	84.71	0.00e+00	1880.00
IUUC-Mcc-055253	Macaca mulatta	84.90	0.00e+00	1754.00
IUUC-Meu-056509	Macropus eugenii	84.40	0.00e+00	820.00
IUUC-Mga-059600	Meleagris gallopavo	75.88	0.00e+00	1697.00
IUUC-Mmr-061586	Microcebus murinus	83.20	0.00e+00	1679.00
IUUC-Mdo-062126	Monodelphis domestica	76.83	0.00e+00	1671.00
IUUC-Mmu-063164	Mus musculus	77.94	0.00e+00	1592.00
IUUC-Mpu-065992	Mustela putorius furo	96.04	0.00e+00	2140.00
IUUC-Mlu-067728	Myotis lucifugus	81.59	0.00e+00	1700.00
IUUC-Nle-069546	Nomascus leucogenys	85.71	0.00e+00	1748.00
IUUC-Opr-070872	Ochotona princeps	82.04	0.00e+00	1704.00
IUUC-Ont-072296	Oreochromis niloticus	86.73	0.00e+00	914.00
IUUC-Ocu-074068	Oryctolagus cuniculus	83.77	0.00e+00	1740.00
IUUC-Ola-086756	Oryzias latipes	60.25	0.00e+00	1187.00
IUUC-Oga-089066	Otolemur garnettii	85.18	0.00e+00	1835.00
IUUC-Oar-090416	Ovis aries	85.37	0.00e+00	1007.00
IUUC-Ptr-091247	Pan troglodytes	85.20	0.00e+00	1765.00
IUUC-Pan-092438	Papio anubis	85.08	0.00e+00	1759.00
IUUC-Psi-093920	Pelodiscus sinensis	75.88	0.00e+00	1691.00
IUUC-Pfo-096334	Poecilia formosa	85.45	0.00e+00	893.00
IUUC-Pab-098452	Pongo abelii	84.62	0.00e+00	1775.00
IUUC-Pca-101081	Procavia capensis	79.58	0.00e+00	1751.00
IUUC-Rno-105102	Rattus norvegicus	78.49	0.00e+00	1581.00
IUUC-Sha-106917	Sarcophilus harrisii	76.75	0.00e+00	1687.00
IUUC-Sar-113711	Sorex araneus	80.30	0.00e+00	1570.00
IUUC-Tgu-116553	Taeniopygia guttata	76.99	0.00e+00	1685.00
IUUC-Tru-118069	Takifugu rubripes	85.71	0.00e+00	901.00
IUUC-Tni-120617	Tetraodon nigroviridis	59.96	0.00e+00	1186.00
IUUC-Ttr-129256	Tursiops truncatus	80.82	0.00e+00	1080.00
IUUC-Xtr-132593	Xenopus tropicalis	71.13	0.00e+00	1525.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence