iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.20e-10	40.7	759	811

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlvi.ekeeqdegWlkgvkelegkrGlfPenF 58
           +v +l+dy+a+  deL++++G+ v+v+  +  ++ +W+ +   l+g++G +P n+
   Q: 759  VVYALWDYSAEFGDELSFREGESVTVLrRDGPEETDWWWA--ALHGQEGYVPRNY 811
           6889***********************8777788999999..8***********9 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MDSEAFQQAR DLLDLNFQSL AMKHMDLKQM ELDTAAAKVD ELTKQLESLW SDSPAPPGTQ 60
AGVPSRMSRY STSPVPEHFG SRGSLQKIAA DGVEARFGRS ESAPSLHPYS PLSPKGRPSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACAGCG AGGCATTCCA ACAGGCGAGG GACCTTCTGG ATCTGAACTT CCAGTGTAAG 60
CTGGCAGCCT GGTGGATGAG CAGGGCCCGG TAAGGGGGAG GGGGTGGAGG GGACAACGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0040--ANK repeat
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR002110--Ankyrin_rpt
IPR020683--Ankyrin_rpt-contain_dom
IPR028320--iASPP
IPR001452--SH3_domain

PROSITE

PS50297--ANK_REP_REGION
PS50088--ANK_REPEAT
PS50002--SH3

Pfam

PF12796--Ank_2
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00248--ANK
SM00326--SH3

Gene Ontology

GO:0030054--C:cell junction
GO:0005829--C:cytosol
GO:0045171--C:intercellular bridge
GO:0006915--P:apoptotic process
GO:0060048--P:cardiac muscle contraction
GO:0003215--P:cardiac right ventricle morphogenesis
GO:0031076--P:embryonic camera-type eye development
GO:0042633--P:hair cycle
GO:0035264--P:multicellular organism growth
GO:0048871--P:multicellular organismal homeostasis
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0045597--P:positive regulation of cell differentiation
GO:0009791--P:post-embryonic development
GO:0006351--P:transcription, DNA-templated
GO:0003229--P:ventricular cardiac muscle tissue development

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001236	Ailuropoda melanoleuca	85.94	0.00e+00	647.00
IUUC-Aca-004907	Anolis carolinensis	79.70	3.00e-98	352.00
IUUC-Bta-012555	Bos taurus	84.59	0.00e+00	1078.00
IUUC-Cfa-020223	Canis familiaris	85.07	0.00e+00	630.00
IUUC-Cpo-022180	Cavia porcellus	77.93	0.00e+00	1108.00
IUUC-Csa-023984	Chlorocebus sabaeus	93.37	1.00e-157	549.00
IUUC-Dre-027600	Danio rerio	49.00	1.00e-91	330.00
IUUC-Dno-029486	Dasypus novemcinctus	87.03	0.00e+00	743.00
IUUC-Dor-030334	Dipodomys ordii	87.10	6.00e-163	568.00
IUUC-Eca-033590	Equus caballus	83.80	0.00e+00	671.00
IUUC-Gac-041648	Gasterosteus aculeatus	51.47	2.00e-95	343.00
IUUC-Hsa-046974	Homo sapiens	93.54	6.00e-162	564.00
IUUC-Itr-048093	Ictidomys tridecemlineatus	83.15	0.00e+00	1016.00
IUUC-Lch-049426	Latimeria chalumnae	56.39	3.00e-95	342.00
IUUC-Laf-054593	Loxodonta africana	84.50	0.00e+00	1113.00
IUUC-Mcc-055896	Macaca mulatta	82.92	6.00e-162	564.00
IUUC-Mmr-061007	Microcebus murinus	79.26	0.00e+00	1009.00
IUUC-Mmu-063188	Mus musculus	94.68	0.00e+00	1292.00
IUUC-Mac-065548	Musa acuminata	34.52	7.00e-06	45.80
IUUC-Mpu-066381	Mustela putorius furo	86.57	7.00e-179	620.00
IUUC-Nle-069627	Nomascus leucogenys	93.82	1.00e-162	566.00
IUUC-Ont-071459	Oreochromis niloticus	49.17	2.00e-90	327.00
IUUC-Ocu-074924	Oryctolagus cuniculus	73.73	5.00e-116	410.00
IUUC-Obr-076350	Oryza brachyantha	34.07	5.00e-03	35.40
IUUC-Olo-080981	Oryza longistaminata	34.07	8.00e-03	35.00
IUUC-Ola-087294	Oryzias latipes	50.45	4.00e-94	339.00
IUUC-Oga-088356	Otolemur garnettii	85.03	0.00e+00	1133.00
IUUC-Oar-089777	Ovis aries	92.86	6.00e-156	544.00
IUUC-Ptr-090843	Pan troglodytes	83.42	3.00e-162	565.00
IUUC-Pfo-096934	Poecilia formosa	51.53	7.00e-98	351.00
IUUC-Pab-098564	Pongo abelii	93.82	4.00e-163	567.00
IUUC-Pca-100382	Procavia capensis	76.69	0.00e+00	873.00
IUUC-Pva-102159	Pteropus vampyrus	93.47	3.00e-166	578.00
IUUC-Tru-117623	Takifugu rubripes	51.46	1.00e-93	337.00
IUUC-Tni-120255	Tetraodon nigroviridis	53.69	1.00e-94	340.00
IUUC-Xtr-132435	Xenopus tropicalis	70.80	3.00e-90	326.00
IUUC-Xma-133548	Xiphophorus maculatus	51.13	3.00e-94	339.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence