iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Aml-001631

Ensembl Protein ID

ENSAMEP00000003023.1

UniProt Accession

G1L807; G1L807_AILME

Genbank Protein ID

ENSAMEP00000003023

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ACTA01152213

Gene Name

ARHGEF6

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMEG00000002774.1	ENSAMET00000003149.1	ENSAMEP00000003023.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.40e-14	52.6	164	218

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            v++ ++++ +n+deL+  kGd+++v     +++gW++g  +l+g+ G fP+n+v++++
   Q: 164  IVKARFNFKQTNEDELSVCKGDIIYVT--RVEEGGWWEG--TLNGRTGWFPSNYVREIK 218
           68999*********************7..999*******..8**************997 PP

Organism

Ailuropoda melanoleuca

Protein Sequence
(Fasta)

MNPEERIVTW LISLGVLDSP KKTICDPEEF LKSSLKNGVV LCKLLSRLRP GSLEKYCAEP 60
QTEADCLSNI ADFLKGCATL QVEVFDPDDL YSGVNFSKVL STLLAVNKAT EDQLSERPCG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAATCCAG AAGAGAGAAT CGTGACATGG CTTATATCCT TGGGAGTTTT AGATTCCCCC 60
AAAAAGACCA TCTGTGATCC GGAGGAGTTC TTGAAGTCCT CGCTGAAGAA TGGGGTAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0344--Guanine-nucleotide releasing factor
KW-1185--Reference proteome

Interpro

IPR001715--CH-domain
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR032409--GEF_CC
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain

PROSITE

PS50021--CH
PS00741--DH_1
PS50010--DH_2
PS50003--PH_DOMAIN
PS50002--SH3

Pfam

PF16523--betaPIX_CC
PF00307--CH
PF00169--PH
PF00621--RhoGEF
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00033--CH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0035556--P:intracellular signal transduction
GO:0035023--P:regulation of Rho protein signal transduction

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-003960	Anas platyrhynchos	66.32	0.00e+00	1051.00
IUUC-Aca-004988	Anolis carolinensis	62.30	0.00e+00	972.00
IUUC-Bta-013527	Bos taurus	82.37	0.00e+00	1305.00
IUUC-Cja-018935	Callithrix jacchus	79.12	0.00e+00	1262.00
IUUC-Cfa-021269	Canis familiaris	83.53	0.00e+00	1306.00
IUUC-Cpo-021620	Cavia porcellus	78.15	0.00e+00	1239.00
IUUC-Csa-023415	Chlorocebus sabaeus	81.55	0.00e+00	1273.00
IUUC-Dno-029201	Dasypus novemcinctus	80.16	0.00e+00	1272.00
IUUC-Dor-030868	Dipodomys ordii	64.62	0.00e+00	937.00
IUUC-Eca-033500	Equus caballus	82.60	0.00e+00	1285.00
IUUC-Eeu-035269	Erinaceus europaeus	82.18	2.00e-165	575.00
IUUC-Fca-035683	Felis catus	83.29	0.00e+00	1295.00
IUUC-Fal-037611	Ficedula albicollis	67.02	0.00e+00	1054.00
IUUC-Gga-040940	Gallus gallus	65.58	0.00e+00	1046.00
IUUC-Ggo-044755	Gorilla gorilla	79.81	0.00e+00	1270.00
IUUC-Hsa-046210	Homo sapiens	81.44	0.00e+00	1272.00
IUUC-Lch-049517	Latimeria chalumnae	61.46	0.00e+00	986.00
IUUC-Loc-052393	Lepisosteus oculatus	57.46	0.00e+00	960.00
IUUC-Laf-054196	Loxodonta africana	85.96	0.00e+00	1147.00
IUUC-Mcc-055716	Macaca mulatta	81.55	0.00e+00	1273.00
IUUC-Meu-056285	Macropus eugenii	73.43	0.00e+00	677.00
IUUC-Mtr-058576	Medicago truncatula	44.62	5.00e-11	62.00
IUUC-Mga-060029	Meleagris gallopavo	66.20	0.00e+00	1059.00
IUUC-Mmr-060803	Microcebus murinus	79.70	0.00e+00	1268.00
IUUC-Mdo-062654	Monodelphis domestica	70.80	0.00e+00	1147.00
IUUC-Mmu-063479	Mus musculus	83.57	0.00e+00	1115.00
IUUC-Mpu-066065	Mustela putorius furo	84.57	0.00e+00	1304.00
IUUC-Mlu-068222	Myotis lucifugus	80.53	0.00e+00	1244.00
IUUC-Nle-069379	Nomascus leucogenys	81.90	0.00e+00	1279.00
IUUC-Opr-070687	Ochotona princeps	72.23	0.00e+00	806.00
IUUC-Oan-073067	Ornithorhynchus anatinus	71.23	0.00e+00	1154.00
IUUC-Ocu-074852	Oryctolagus cuniculus	80.74	0.00e+00	1252.00
IUUC-Oga-089048	Otolemur garnettii	82.89	0.00e+00	1311.00
IUUC-Oar-089339	Ovis aries	82.02	0.00e+00	1299.00
IUUC-Pan-092666	Papio anubis	77.43	0.00e+00	1216.00
IUUC-Psi-093116	Pelodiscus sinensis	66.09	0.00e+00	1075.00
IUUC-Pab-098567	Pongo abelii	82.13	0.00e+00	1281.00
IUUC-Pca-100997	Procavia capensis	73.47	0.00e+00	928.00
IUUC-Pva-102500	Pteropus vampyrus	79.70	0.00e+00	1250.00
IUUC-Rno-104974	Rattus norvegicus	84.13	0.00e+00	1098.00
IUUC-Sar-113420	Sorex araneus	80.64	0.00e+00	1066.00
IUUC-Ssc-115679	Sus scrofa	81.36	0.00e+00	1120.00
IUUC-Tgu-117069	Taeniopygia guttata	66.90	0.00e+00	1063.00
IUUC-Tru-118488	Takifugu rubripes	54.53	0.00e+00	820.00
IUUC-Tsy-119243	Tarsius syrichta	71.23	0.00e+00	838.00
IUUC-Tni-120584	Tetraodon nigroviridis	57.16	0.00e+00	793.00
IUUC-Tbe-127994	Tupaia belangeri	80.22	0.00e+00	876.00
IUUC-Ttr-128839	Tursiops truncatus	86.51	0.00e+00	1133.00
IUUC-Vpa-130144	Vicugna pacos	74.07	0.00e+00	1097.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence