• HOME
  • BROWSE
  • SEARCH
  • LINK
  • DOWNLOAD
  • USER GUIDE
  • Protein
  • Gene
  • Annotation
  • Classification
  • Domain Profile
  • Function
  • Protein Sequence
  • Nucleotide Sequence
  • Keyword
  • GO
  • Orthology
  • TOP

Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-064311
Ensembl Protein ID ENSMUSP00000046951.6
UniProt Accession Q8CFE5; Q80TC3; Q8BZY9; BTBD7_MOUSE
Genbank Protein ID BAC28177.1; BAC65804.1; AAH41669.1; AAH57303.1
Protein Name BTB/POZ domain-containing protein 7; Function-unkown protein 1
Genbank Nucleotide ID AK033160; AK122522; BC041669; BC057303
Gene Name Btbd7; Fup1; Kiaa1525
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000041702.6 ENSMUST00000045652.6 ENSMUSP00000046951.6
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusdbPTM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB 6.10e-20 72.5 142 208
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/BCR/BTB_Other: BTB
   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd..vqpevfrallkFlYtgkld 66
           +Dv l+ +++ f++h+++Laa++++F+ l+++  e +  +  ++i+   ++   f+all++lYtg++ 
   Q: 142  TDVDLIFQETCFPVHRAILAARCPFFKTLLSSSPEYGA-EIIMDISTagIDMPMFSALLHYLYTGEFG 208
           79****************************99888876.6677777356****************975 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression.
 Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression.
Protein Sequence
(Fasta)
MGANASNYPH SCSPRVGGNS QAQQTFIGTS SYSQQGYGCE SKLYSLDHGH EKPQDKKKRT 60
SGLATLKKKF IKRRKSNRSA DHAKQMRELL SGWDVRDVNA LVEEYEGTSA LKELSLQASL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-064311|E3,BTB_Other|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AATGGCGACG GGGGGAACCT GGAGTGGTCC CGGAGCCTAA GCCACTGACA GGAGAGGGGA 60
GGGCGGCGGC GGCGGCTGGA GGAGAATGGC CGCGGGGGCT GGCGCCAGTG CGGACGACGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-064311|E3,BTB_Other|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0449--Lipoprotein
KW-0519--Myristate
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
PROSITE

PS50097--BTB
Pfam

PF07707--BACK
PF00651--BTB
SMART

SM00875--BACK
SM00225--BTB
Gene Ontology

GO:0005634--C:nucleus
GO:0007275--P:multicellular organism development
GO:0060693--P:regulation of branching involved in salivary gland morphogenesis
KEGG mmu:238386
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001669 Ailuropoda melanoleuca 92.76 0.00e+00 2003.00
IUUC-Apl-004146 Anas platyrhynchos 88.41 0.00e+00 1988.00
IUUC-Aca-004531 Anolis carolinensis 85.04 0.00e+00 1820.00
IUUC-Ame-011888 Astyanax mexicanus 66.46 0.00e+00 1338.00
IUUC-Bta-012739 Bos taurus 93.72 0.00e+00 2049.00
IUUC-Cja-019090 Callithrix jacchus 91.98 0.00e+00 2051.00
IUUC-Cfa-021272 Canis familiaris 93.36 0.00e+00 2011.00
IUUC-Cpo-021381 Cavia porcellus 89.77 0.00e+00 2018.00
IUUC-Csa-023734 Chlorocebus sabaeus 92.81 0.00e+00 1956.00
IUUC-Cho-024830 Choloepus hoffmanni 72.42 4.00e-130 459.00
IUUC-Dre-027552 Danio rerio 67.19 0.00e+00 1397.00
IUUC-Dno-028927 Dasypus novemcinctus 92.83 0.00e+00 2047.00
IUUC-Dor-030455 Dipodomys ordii 86.22 0.00e+00 1100.00
IUUC-Dme-031575 Drosophila melanogaster 46.53 3.00e-157 549.00
IUUC-Ete-032546 Echinops telfairi 81.33 0.00e+00 1656.00
IUUC-Eca-033548 Equus caballus 91.42 0.00e+00 1957.00
IUUC-Fca-036539 Felis catus 93.54 0.00e+00 2041.00
IUUC-Fal-037224 Ficedula albicollis 84.50 0.00e+00 1945.00
IUUC-Gmo-039413 Gadus morhua 80.36 0.00e+00 647.00
IUUC-Gga-040778 Gallus gallus 93.81 0.00e+00 735.00
IUUC-Gac-041839 Gasterosteus aculeatus 65.11 0.00e+00 1389.00
IUUC-Ggo-045450 Gorilla gorilla 93.12 0.00e+00 2043.00
IUUC-Hsa-046103 Homo sapiens 93.12 0.00e+00 2078.00
IUUC-Itr-048595 Ictidomys tridecemlineatus 98.97 0.00e+00 801.00
IUUC-Lch-050622 Latimeria chalumnae 80.62 0.00e+00 1780.00
IUUC-Loc-052889 Lepisosteus oculatus 73.84 0.00e+00 1563.00
IUUC-Laf-053392 Loxodonta africana 92.12 0.00e+00 2003.00
IUUC-Mcc-055838 Macaca mulatta 93.06 0.00e+00 2013.00
IUUC-Meu-056638 Macropus eugenii 78.10 0.00e+00 1469.00
IUUC-Mtr-058684 Medicago truncatula 30.43 2.00e-04 41.20
IUUC-Mga-059339 Meleagris gallopavo 86.78 0.00e+00 1973.00
IUUC-Mmr-061046 Microcebus murinus 92.50 0.00e+00 2034.00
IUUC-Mdo-062182 Monodelphis domestica 92.77 0.00e+00 1604.00
IUUC-Mpu-066893 Mustela putorius furo 93.01 0.00e+00 2034.00
IUUC-Mlu-067087 Myotis lucifugus 91.89 0.00e+00 2000.00
IUUC-Nle-069780 Nomascus leucogenys 92.95 0.00e+00 2008.00
IUUC-Opr-070487 Ochotona princeps 85.88 0.00e+00 990.00
IUUC-Ont-071582 Oreochromis niloticus 65.04 0.00e+00 1393.00
IUUC-Oan-072900 Ornithorhynchus anatinus 88.11 0.00e+00 1914.00
IUUC-Ocu-073746 Oryctolagus cuniculus 93.88 0.00e+00 1735.00
IUUC-Ola-086582 Oryzias latipes 64.62 0.00e+00 1370.00
IUUC-Oga-088013 Otolemur garnettii 92.43 0.00e+00 2011.00
IUUC-Oar-089234 Ovis aries 91.77 0.00e+00 2002.00
IUUC-Ptr-091490 Pan troglodytes 93.21 0.00e+00 2034.00
IUUC-Pan-092592 Papio anubis 93.06 0.00e+00 2012.00
IUUC-Psi-093163 Pelodiscus sinensis 88.24 0.00e+00 1895.00
IUUC-Pma-094133 Petromyzon marinus 55.01 7.00e-84 303.00
IUUC-Pfo-096674 Poecilia formosa 64.30 0.00e+00 1381.00
IUUC-Pab-098305 Pongo abelii 93.13 0.00e+00 2053.00
IUUC-Pva-102998 Pteropus vampyrus 92.30 0.00e+00 2051.00
IUUC-Rno-105445 Rattus norvegicus 97.17 0.00e+00 2044.00
IUUC-Sha-106737 Sarcophilus harrisii 89.12 0.00e+00 1904.00
IUUC-Sar-113474 Sorex araneus 97.60 0.00e+00 1186.00
IUUC-Ssc-116111 Sus scrofa 93.27 0.00e+00 2045.00
IUUC-Tgu-117204 Taeniopygia guttata 87.20 0.00e+00 1947.00
IUUC-Tru-118753 Takifugu rubripes 64.74 0.00e+00 1387.00
IUUC-Tsy-119632 Tarsius syrichta 90.67 0.00e+00 1966.00
IUUC-Tni-120088 Tetraodon nigroviridis 64.11 0.00e+00 1385.00
IUUC-Tbe-127435 Tupaia belangeri 95.41 0.00e+00 1337.00
IUUC-Ttr-128912 Tursiops truncatus 87.70 0.00e+00 1862.00
IUUC-Vpa-130654 Vicugna pacos 98.71 0.00e+00 1354.00
IUUC-Xtr-132530 Xenopus tropicalis 82.11 0.00e+00 1851.00
Created Date 25-Jun-2017

https://dev.news.makassarkota.go.id/public/pgsoft-demo/ https://jdih.sumbawabaratkab.go.id/lato/pg-soft-demo/ https://dev.news.makassarkota.go.id/public/slot-gacor/ http://pbb.tanahbumbukab.go.id/-/slot-gacor/ slot gacor https://siakad.unipra.ac.id/sass/slot-gacor-x500/ http://kpm.dinus.ac.id/assets/images/berita/slot/
Copyright © 2004-2017.The CUCKOO Workgroup. All Rights Reserved