iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mtr-058555

Ensembl Protein ID

AES99834

UniProt Accession

G7KH91; A0A0C3XS46; G7KH91_MEDTR

Genbank Protein ID

AES99834.2

Protein Name

E3 ubiquitin-protein ligase COP1

Genbank Nucleotide ID

CM001221

Gene Name

MTR_5g085250

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
MTR_5g085250	AES99834	AES99834
MTR_5g085250	KEH28313	KEH28313

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	1.10e-08	36.4	48	112
E3 adaptor/Cullin RING/DCX/DWD	7.90e-31	106.2	549	586
UBD/Beta-Prp	4.80e-41	142.3	373	674

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawc 69
           ++flCpI +++ +d   +++G+++   +I  +l+++   cP +++ lt+++l Pn  l +l ++  
   Q: 48   KDFLCPICMQIIKDAFLTSCGHSFCYMCIITHLRNKSD-CPCCGHYLTNSNLFPNFLLDKLLKKTS 112
           78*********************************999.****************99987776655 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sdtllvsGsdDgtikvWDlrtgvllk 37
           gH+  v+ ++f s++ l+s+s D t+++WD++++v+++
   Q: 549  GHKKAVSYVKFlSNDELASASTDSTLRLWDVKQNVPVR 586
           8999*******98899*****************99987 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkl........lrslsgheaevtavkfspdgk.ilvtgseDrtikvwdlstgkcvhtlkghedsvlsls 101
            + ++++ f +d++l+at++ +++ikv+d++            + ++   + + +++++++ +k  ++++   +++ vwd+ t+k ++ +++he++++s++
   Q: 373  ANIVSSIEFDRDDDLFATAGVSRRIKVFDFSAVVNeptdahcpVVEMTTRS-KLSCLSWNKYAKnQIASSDYEGIVTVWDVTTRKSLMEYEEHEKRAWSVD 472
           567899*************************94446666665544444333.499999999987456666666**************************** PP
   S: 102  fspsg.dklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdl.ktgkllrtltgghtdsvyslsfdsngkelvsgs 199
           fs+++ + lvsGs+d  ++vw ++++  + +++   ++ ++cv+++p + n+++ Gs+D  +  +dl +  + ++ ++g h+++v  ++f sn  el+s+s
   Q: 473  FSRTDpSMLVSGSDDCKVKVWCTNQEASVLNIDM--KANICCVKYNPGSgNYIAVGSADHHIHYYDLrNISRPVHVFSG-HKKAVSYVKFLSN-DELASAS 569
           ***888***************7777777754444..4559*******99******************556899*****9.************8.6****** PP
   S: 200  ldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW..dlrsgdllktlqlhn.........ssvisvavlsfgdnvlvlgsedskv 289
           +d+t++lwd++++  vrt++gh +  + v ++  +e++++gs+ + ++++   + +  +++ ++ +          s +is  +++ +++ ++++ + +++
   Q: 570  TDSTLRLWDVKQNVPVRTFRGHANEKNFVGLTVSSEYIACGSETNEVFVYhkEISKPLTWHRFSSPDmddaedeagSYFISAVCWKSDRPTILTANSQGTI 670
           **************************************************55555555666666666********999999999***************** PP
   S: 290  niwk 293
           +++ 
   Q: 671  KVLV 674
           9975 PP

Organism

Medicago truncatula

Protein Sequence
(Fasta)

MEEHSVGPLV PAVVKPEPSK NLSTTVTVTG DIAGGDNFPI ATMTELDKDF LCPICMQIIK 60
DAFLTSCGHS FCYMCIITHL RNKSDCPCCG HYLTNSNLFP NFLLDKLLKK TSDRQISKTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACGTGGAAA TATCTCACCC TCACAAACAT CACATTCCTG GACCCACTTT CTTCCACTCT 60
AAACCCGCTT CTCTTCAAAT CACCACCACA CGCATCAAAA CCATTTCATC TCAAAAACCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00400--WD40

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0016604--C:nuclear body
GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0046283--P:anthocyanin-containing compound metabolic process
GO:0006281--P:DNA repair
GO:0009649--P:entrainment of circadian clock
GO:0009640--P:photomorphogenesis
GO:0048573--P:photoperiodism, flowering
GO:0010119--P:regulation of stomatal movement
GO:0009641--P:shade avoidance

KEGG

mtr:MTR_5g085250

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000885	Aegilops tauschii	70.28	0.00e+00	927.00
IUUC-Aml-001265	Ailuropoda melanoleuca	40.33	4.00e-127	447.00
IUUC-Atr-002460	Amborella trichopoda	76.89	0.00e+00	971.00
IUUC-Apl-003796	Anas platyrhynchos	40.54	5.00e-121	427.00
IUUC-Aca-005078	Anolis carolinensis	40.87	4.00e-126	444.00
IUUC-Aly-006014	Arabidopsis lyrata	77.65	0.00e+00	1094.00
IUUC-Ath-007636	Arabidopsis thaliana	77.50	0.00e+00	1095.00
IUUC-Ame-011176	Astyanax mexicanus	56.20	1.00e-39	157.00
IUUC-Bta-012595	Bos taurus	40.45	8.00e-128	450.00
IUUC-Bdi-014152	Brachypodium distachyon	69.21	0.00e+00	949.00
IUUC-Bol-016380	Brassica oleracea	76.83	0.00e+00	1055.00
IUUC-Bra-017690	Brassica rapa	76.13	0.00e+00	1038.00
IUUC-Cja-018926	Callithrix jacchus	40.36	1.00e-127	450.00
IUUC-Cfa-021088	Canis familiaris	40.64	1.00e-127	449.00
IUUC-Cpo-022442	Cavia porcellus	40.06	1.00e-121	429.00
IUUC-Cre-022579	Chlamydomonas reinhardtii	32.48	5.00e-37	147.00
IUUC-Csa-024119	Chlorocebus sabaeus	40.30	4.00e-127	448.00
IUUC-Cin-025375	Ciona intestinalis	37.81	2.00e-120	425.00
IUUC-Cme-027350	Cyanidioschyzon merolae	43.53	3.00e-90	326.00
IUUC-Dre-028453	Danio rerio	40.62	5.00e-127	447.00
IUUC-Dno-029887	Dasypus novemcinctus	39.91	2.00e-128	452.00
IUUC-Dor-031110	Dipodomys ordii	53.27	8.00e-94	337.00
IUUC-Ete-033016	Echinops telfairi	53.27	1.00e-93	337.00
IUUC-Eca-034403	Equus caballus	40.22	3.00e-120	425.00
IUUC-Eeu-034690	Erinaceus europaeus	53.90	7.00e-89	320.00
IUUC-Fca-036475	Felis catus	40.54	9.00e-122	429.00
IUUC-Fal-037189	Ficedula albicollis	40.83	1.00e-126	446.00
IUUC-Gmo-039245	Gadus morhua	39.63	4.00e-119	421.00
IUUC-Gga-040806	Gallus gallus	40.80	2.00e-127	449.00
IUUC-Gac-042177	Gasterosteus aculeatus	39.42	5.00e-124	437.00
IUUC-Gma-044187	Glycine max	91.29	0.00e+00	1256.00
IUUC-Ggo-044430	Gorilla gorilla	36.69	2.00e-80	293.00
IUUC-Hsa-045853	Homo sapiens	40.39	8.00e-128	450.00
IUUC-Itr-048238	Ictidomys tridecemlineatus	53.74	3.00e-72	263.00
IUUC-Lch-050420	Latimeria chalumnae	40.74	1.00e-126	446.00
IUUC-Lpe-051219	Leersia perrieri	73.09	0.00e+00	939.00
IUUC-Loc-052728	Lepisosteus oculatus	41.49	3.00e-122	432.00
IUUC-Laf-053775	Loxodonta africana	40.33	4.00e-128	451.00
IUUC-Meu-056595	Macropus eugenii	41.24	8.00e-59	221.00
IUUC-Mga-059646	Meleagris gallopavo	40.35	1.00e-120	426.00
IUUC-Mmr-060990	Microcebus murinus	40.33	6.00e-127	447.00
IUUC-Mdo-062287	Monodelphis domestica	40.54	6.00e-128	451.00
IUUC-Mmu-064097	Mus musculus	40.80	1.00e-127	449.00
IUUC-Mac-065240	Musa acuminata	71.45	0.00e+00	983.00
IUUC-Mpu-066612	Mustela putorius furo	40.51	8.00e-121	426.00
IUUC-Mlu-067967	Myotis lucifugus	40.10	5.00e-119	421.00
IUUC-Nle-069543	Nomascus leucogenys	40.39	1.00e-127	449.00
IUUC-Opr-070366	Ochotona princeps	45.69	1.00e-45	177.00
IUUC-Ont-071522	Oreochromis niloticus	48.59	6.00e-107	380.00
IUUC-Oan-073409	Ornithorhynchus anatinus	40.32	6.00e-119	420.00
IUUC-Ocu-073756	Oryctolagus cuniculus	40.92	1.00e-123	436.00
IUUC-Oba-075149	Oryza barthii	70.38	0.00e+00	954.00
IUUC-Obr-076563	Oryza brachyantha	73.43	0.00e+00	955.00
IUUC-Ogl-077701	Oryza glaberrima	70.72	0.00e+00	959.00
IUUC-Ogu-078383	Oryza glumaepatula	70.72	0.00e+00	959.00
IUUC-Oin-079965	Oryza indica	69.58	0.00e+00	877.00
IUUC-Olo-080639	Oryza longistaminata	71.49	0.00e+00	942.00
IUUC-Ome-081821	Oryza meridionalis	73.21	0.00e+00	885.00
IUUC-Oni-082622	Oryza nivara	70.72	0.00e+00	959.00
IUUC-Opu-083295	Oryza punctata	70.10	0.00e+00	964.00
IUUC-Oru-084661	Oryza rufipogon	70.72	0.00e+00	959.00
IUUC-Osa-085766	Oryza sativa	70.72	0.00e+00	959.00
IUUC-Ola-086727	Oryzias latipes	40.18	5.00e-126	444.00
IUUC-Oga-088215	Otolemur garnettii	40.19	3.00e-123	435.00
IUUC-Oar-089880	Ovis aries	40.19	4.00e-123	434.00
IUUC-Ptr-090597	Pan troglodytes	40.39	8.00e-128	450.00
IUUC-Pan-091987	Papio anubis	40.39	8.00e-128	450.00
IUUC-Psi-094033	Pelodiscus sinensis	40.50	2.00e-122	432.00
IUUC-Pma-094587	Petromyzon marinus	39.24	1.00e-111	396.00
IUUC-Ppa-095401	Physcomitrella patens	60.66	0.00e+00	820.00
IUUC-Pfo-097388	Poecilia formosa	39.20	2.00e-123	436.00
IUUC-Pab-098029	Pongo abelii	40.39	8.00e-128	450.00
IUUC-Pop-099319	Populus trichocarpa	78.17	0.00e+00	1097.00
IUUC-Pca-100846	Procavia capensis	48.72	3.00e-106	378.00
IUUC-Ppe-101250	Prunus persica	64.26	0.00e+00	861.00
IUUC-Pva-102407	Pteropus vampyrus	39.79	1.00e-123	436.00
IUUC-Rno-105312	Rattus norvegicus	40.80	1.00e-127	449.00
IUUC-Sha-106514	Sarcophilus harrisii	48.50	9.00e-102	362.00
IUUC-Smo-109418	Selaginella moellendorffii	61.83	0.00e+00	792.00
IUUC-Sit-110248	Setaria italica	72.99	0.00e+00	952.00
IUUC-Sly-110895	Solanum lycopersicum	75.44	0.00e+00	1064.00
IUUC-Stu-112386	Solanum tuberosum	72.55	0.00e+00	1010.00
IUUC-Sar-113230	Sorex araneus	44.85	8.00e-71	260.00
IUUC-Sbi-113962	Sorghum bicolor	66.80	0.00e+00	935.00
IUUC-Ssc-115987	Sus scrofa	29.10	2.00e-26	112.00
IUUC-Tgu-116471	Taeniopygia guttata	40.33	6.00e-127	447.00
IUUC-Tru-118231	Takifugu rubripes	38.46	6.00e-113	400.00
IUUC-Tsy-119415	Tarsius syrichta	39.88	1.00e-118	419.00
IUUC-Tni-120893	Tetraodon nigroviridis	37.50	6.00e-110	390.00
IUUC-Tca-121619	Theobroma cacao	77.30	0.00e+00	1098.00
IUUC-Tae-125440	Triticum aestivum	71.54	0.00e+00	955.00
IUUC-Tur-126557	Triticum urartu	70.75	0.00e+00	927.00
IUUC-Tbe-127253	Tupaia belangeri	45.10	2.00e-72	266.00
IUUC-Ttr-129100	Tursiops truncatus	39.75	9.00e-118	416.00
IUUC-Vpa-130613	Vicugna pacos	36.73	2.00e-103	369.00
IUUC-Vvi-131386	Vitis vinifera	74.08	0.00e+00	1020.00
IUUC-Xtr-132033	Xenopus tropicalis	40.91	2.00e-134	472.00
IUUC-Xma-133421	Xiphophorus maculatus	39.20	1.00e-123	436.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence