iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	5.90e-12	46.2	31	97

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikd.vqpevfrallkFlYtgklde 67
           +Dv++vv+g++f+ahk vL  sS++F+ l  +  + s++   +++ d v ++ f+a+++F+Y+  l +
   Q: 31   CDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSDQATVTHL-DiVTAQGFKAIIDFMYSAHLAL 97
           9*****************************999898884555555.55**************998865 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MNNRKEDMEI TSHYRHLLRE LNEQRQHGVL CDVCVVVEGK VFKAHKNVLL GSSRYFKTLY 60
CQVQKTSDQA TVTHLDIVTA QGFKAIIDFM YSAHLALTSR NVIEVMSAAS FLQMTDIVQA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CACCGGTCCG CGGCCACGGC GCCAGCCCGC GCCCGCGCCC CATGGGGTCA CAGGTAAGCT 60
GCGCCGGCTC ATTGTCCGCG CGGCCGGGCT GGCGCACCAC GCCGGGGCCG GGGCTAAAGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000210--BTB/POZ_dom
IPR004039--Rubredoxin-type_fold
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0046872--F:metal ion binding
GO:0003676--F:nucleic acid binding
GO:2001199--P:negative regulation of dendritic cell differentiation
GO:0030853--P:negative regulation of granulocyte differentiation
GO:0045650--P:negative regulation of macrophage differentiation
GO:0045656--P:negative regulation of monocyte differentiation
GO:2001200--P:positive regulation of dendritic cell differentiation

KEGG

rno:311718

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002267	Ailuropoda melanoleuca	91.04	0.00e+00	927.00
IUUC-Apl-004220	Anas platyrhynchos	80.90	0.00e+00	969.00
IUUC-Aca-005350	Anolis carolinensis	77.20	0.00e+00	935.00
IUUC-Ame-011334	Astyanax mexicanus	61.67	0.00e+00	716.00
IUUC-Bta-012773	Bos taurus	83.36	0.00e+00	948.00
IUUC-Cja-019261	Callithrix jacchus	77.39	0.00e+00	878.00
IUUC-Cfa-021070	Canis familiaris	91.67	0.00e+00	763.00
IUUC-Cpo-021350	Cavia porcellus	92.68	0.00e+00	1050.00
IUUC-Csa-023182	Chlorocebus sabaeus	92.27	0.00e+00	1017.00
IUUC-Cin-025354	Ciona intestinalis	39.20	2.00e-22	100.00
IUUC-Csv-026323	Ciona savignyi	40.00	3.00e-23	103.00
IUUC-Dre-027453	Danio rerio	62.54	0.00e+00	719.00
IUUC-Dno-029375	Dasypus novemcinctus	85.40	0.00e+00	679.00
IUUC-Dor-030991	Dipodomys ordii	70.50	0.00e+00	790.00
IUUC-Eca-033346	Equus caballus	91.78	0.00e+00	986.00
IUUC-Eeu-034489	Erinaceus europaeus	85.78	0.00e+00	708.00
IUUC-Fca-035853	Felis catus	86.52	0.00e+00	981.00
IUUC-Fal-037546	Ficedula albicollis	79.20	0.00e+00	939.00
IUUC-Gmo-038589	Gadus morhua	82.00	2.00e-72	264.00
IUUC-Gga-040354	Gallus gallus	80.07	0.00e+00	948.00
IUUC-Ggo-045007	Gorilla gorilla	91.47	0.00e+00	1000.00
IUUC-Hsa-046360	Homo sapiens	91.53	0.00e+00	1009.00
IUUC-Itr-048566	Ictidomys tridecemlineatus	89.68	0.00e+00	1023.00
IUUC-Lch-050668	Latimeria chalumnae	76.41	0.00e+00	890.00
IUUC-Loc-052410	Lepisosteus oculatus	69.54	0.00e+00	812.00
IUUC-Laf-054523	Loxodonta africana	88.20	0.00e+00	952.00
IUUC-Mcc-055030	Macaca mulatta	93.25	0.00e+00	972.00
IUUC-Meu-056772	Macropus eugenii	81.20	0.00e+00	1002.00
IUUC-Mga-059531	Meleagris gallopavo	78.74	0.00e+00	925.00
IUUC-Mmr-061653	Microcebus murinus	83.55	0.00e+00	988.00
IUUC-Mdo-062023	Monodelphis domestica	82.03	0.00e+00	1022.00
IUUC-Mmu-063957	Mus musculus	98.84	0.00e+00	1163.00
IUUC-Mpu-065784	Mustela putorius furo	88.02	0.00e+00	983.00
IUUC-Mlu-067188	Myotis lucifugus	81.36	0.00e+00	961.00
IUUC-Nle-069839	Nomascus leucogenys	91.04	0.00e+00	909.00
IUUC-Ont-071549	Oreochromis niloticus	61.30	0.00e+00	707.00
IUUC-Oan-073288	Ornithorhynchus anatinus	79.01	0.00e+00	1004.00
IUUC-Ocu-074031	Oryctolagus cuniculus	66.28	0.00e+00	701.00
IUUC-Ola-087013	Oryzias latipes	61.49	0.00e+00	707.00
IUUC-Oga-089158	Otolemur garnettii	84.88	0.00e+00	963.00
IUUC-Oar-090145	Ovis aries	81.24	0.00e+00	764.00
IUUC-Ptr-090525	Pan troglodytes	90.42	0.00e+00	993.00
IUUC-Pan-092450	Papio anubis	92.08	0.00e+00	1015.00
IUUC-Psi-093791	Pelodiscus sinensis	80.53	0.00e+00	981.00
IUUC-Pfo-096728	Poecilia formosa	57.84	0.00e+00	689.00
IUUC-Pab-098690	Pongo abelii	93.02	0.00e+00	936.00
IUUC-Pva-103107	Pteropus vampyrus	84.35	0.00e+00	685.00
IUUC-Sha-107445	Sarcophilus harrisii	82.03	0.00e+00	1014.00
IUUC-Sar-113744	Sorex araneus	78.43	8.00e-171	592.00
IUUC-Tgu-117181	Taeniopygia guttata	83.33	0.00e+00	937.00
IUUC-Tru-117668	Takifugu rubripes	60.69	0.00e+00	703.00
IUUC-Tsy-119528	Tarsius syrichta	93.44	2.00e-166	578.00
IUUC-Tni-120403	Tetraodon nigroviridis	80.99	1.00e-65	243.00
IUUC-Tbe-128061	Tupaia belangeri	72.79	2.00e-165	575.00
IUUC-Ttr-128681	Tursiops truncatus	89.08	0.00e+00	814.00
IUUC-Xma-133121	Xiphophorus maculatus	61.13	0.00e+00	639.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence