iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSDARG00000074121.4	ENSDART00000153129.1	ENSDARP00000127379.1
ENSDARG00000074121.4	ENSDART00000152971.1	ENSDARP00000127353.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.20e-49	167.1	264	314

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
            ++ly++ a + +eL +  Gd ++++  ++ d gWl+g  + + +rG+fP+ Fv+
   Q: 264  GIALYEFRALEPGELDFDVGDRIRIL--ASMDDGWLEG--QIHSRRGVFPHRFVK 314
           579***********************..**********..7************97 PP

Organism

Danio rerio

Protein Sequence
(Fasta)

MEAGSVVRAV FEFLPSVSEE LPLFTGDVIE VLSVVDEFWL LGNKDGVTGQ FPTTFVESVT 60
IPGTKAGENL YVCINDFNSA EAGNLPLKRG DVVAAESSMD SVWMRGHNAW GSRGLFPVSC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCTTCAGGCA TGTGGAAGGC AGCCCTGCGC TTGCTGTCAG CAGAGGGTGG TGTGTGTGTG 60
TTGATGTTGA TGTCAGCATG GAGGCAGTTC AGGATCAGCC TGCTCATGCT GGCGCTTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR004148--BAR_dom
IPR000219--DH-domain
IPR001331--GDS_CDC24_CS
IPR011511--SH3_2
IPR001452--SH3_domain

PROSITE

PS51021--BAR
PS00741--DH_1
PS50010--DH_2
PS50002--SH3

Pfam

PF03114--BAR
PF00621--RhoGEF
PF07653--SH3_2
PF14604--SH3_9

SMART

SM00721--BAR
SM00325--RhoGEF
SM00326--SH3

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0060271--P:cilium assembly
GO:0001822--P:kidney development
GO:0043547--P:positive regulation of GTPase activity
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction

KEGG

dre:100005174

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002128	Ailuropoda melanoleuca	63.90	0.00e+00	867.00
IUUC-Apl-003934	Anas platyrhynchos	66.11	0.00e+00	874.00
IUUC-Aca-005005	Anolis carolinensis	65.36	0.00e+00	893.00
IUUC-Ame-011361	Astyanax mexicanus	79.18	0.00e+00	1315.00
IUUC-Bta-013210	Bos taurus	55.96	0.00e+00	913.00
IUUC-Cel-018396	Caenorhabditis elegans	26.50	3.00e-31	131.00
IUUC-Cja-019104	Callithrix jacchus	56.00	0.00e+00	925.00
IUUC-Cfa-020960	Canis familiaris	63.50	0.00e+00	870.00
IUUC-Cpo-022440	Cavia porcellus	60.70	0.00e+00	887.00
IUUC-Csa-023391	Chlorocebus sabaeus	58.19	0.00e+00	971.00
IUUC-Cho-024795	Choloepus hoffmanni	47.95	0.00e+00	739.00
IUUC-Cin-025137	Ciona intestinalis	35.68	2.00e-33	135.00
IUUC-Dno-029750	Dasypus novemcinctus	57.33	0.00e+00	963.00
IUUC-Dor-031109	Dipodomys ordii	61.03	0.00e+00	862.00
IUUC-Ete-032660	Echinops telfairi	58.33	0.00e+00	716.00
IUUC-Eca-033433	Equus caballus	57.64	0.00e+00	949.00
IUUC-Eeu-034929	Erinaceus europaeus	57.68	1.00e-124	441.00
IUUC-Fca-035859	Felis catus	64.89	0.00e+00	888.00
IUUC-Fal-036653	Ficedula albicollis	57.80	0.00e+00	937.00
IUUC-Gmo-038948	Gadus morhua	74.11	0.00e+00	981.00
IUUC-Gga-040279	Gallus gallus	65.36	0.00e+00	846.00
IUUC-Gac-041641	Gasterosteus aculeatus	68.86	0.00e+00	1220.00
IUUC-Hsa-046063	Homo sapiens	65.52	0.00e+00	898.00
IUUC-Itr-049071	Ictidomys tridecemlineatus	56.28	0.00e+00	939.00
IUUC-Lch-049865	Latimeria chalumnae	60.26	0.00e+00	782.00
IUUC-Loc-051754	Lepisosteus oculatus	70.27	0.00e+00	1295.00
IUUC-Laf-054037	Loxodonta africana	40.09	1.00e-106	382.00
IUUC-Mcc-055002	Macaca mulatta	58.52	0.00e+00	975.00
IUUC-Meu-056420	Macropus eugenii	51.44	0.00e+00	768.00
IUUC-Mga-059868	Meleagris gallopavo	61.47	0.00e+00	834.00
IUUC-Mmr-060767	Microcebus murinus	57.86	0.00e+00	974.00
IUUC-Mdo-061939	Monodelphis domestica	57.85	0.00e+00	941.00
IUUC-Mmu-063980	Mus musculus	54.58	0.00e+00	882.00
IUUC-Mpu-065913	Mustela putorius furo	57.89	0.00e+00	988.00
IUUC-Mlu-067340	Myotis lucifugus	50.84	1.00e-77	285.00
IUUC-Nle-069343	Nomascus leucogenys	58.30	0.00e+00	973.00
IUUC-Opr-070694	Ochotona princeps	55.73	0.00e+00	950.00
IUUC-Ont-071844	Oreochromis niloticus	70.59	0.00e+00	1183.00
IUUC-Oan-073605	Ornithorhynchus anatinus	64.91	3.00e-21	96.70
IUUC-Ocu-074406	Oryctolagus cuniculus	57.97	0.00e+00	984.00
IUUC-Ola-087343	Oryzias latipes	67.28	0.00e+00	788.00
IUUC-Oga-088847	Otolemur garnettii	58.19	0.00e+00	965.00
IUUC-Oar-089817	Ovis aries	61.73	0.00e+00	839.00
IUUC-Pan-092104	Papio anubis	58.62	0.00e+00	970.00
IUUC-Psi-094045	Pelodiscus sinensis	55.35	7.00e-64	239.00
IUUC-Pma-094663	Petromyzon marinus	44.57	1.00e-133	471.00
IUUC-Pfo-096714	Poecilia formosa	67.06	0.00e+00	1178.00
IUUC-Pab-097918	Pongo abelii	58.41	0.00e+00	975.00
IUUC-Pca-101096	Procavia capensis	51.52	5.00e-127	449.00
IUUC-Pva-102490	Pteropus vampyrus	55.61	0.00e+00	968.00
IUUC-Rno-105908	Rattus norvegicus	55.57	0.00e+00	910.00
IUUC-Sha-107509	Sarcophilus harrisii	58.15	0.00e+00	960.00
IUUC-Ssc-115250	Sus scrofa	55.64	0.00e+00	928.00
IUUC-Tru-118279	Takifugu rubripes	65.55	0.00e+00	1200.00
IUUC-Tni-120459	Tetraodon nigroviridis	75.04	0.00e+00	903.00
IUUC-Tbe-127753	Tupaia belangeri	38.36	3.00e-96	347.00
IUUC-Ttr-129096	Tursiops truncatus	61.42	0.00e+00	860.00
IUUC-Vpa-130643	Vicugna pacos	57.67	0.00e+00	719.00
IUUC-Xtr-131979	Xenopus tropicalis	57.83	0.00e+00	1039.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence