iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mcc-054605

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

JSUE03016751

Gene Name

SOCS7

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000020531.3	ENSMMUT00000028895.3	ENSMMUP00000027040.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box	1.10e-13	51.9	551	598

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/ECS/SOCS_VHL_BC-box

   S: 2    sklwllrseprSLqhLCRlaIrrclgsqrlkaidkLPLPksLkdYLlyedy 52
           +++ +++s++ SLqhLCR++Ir++++++++   + LPLPk L++Y++++ y
   Q: 551  LYPVSRFSNVKSLQHLCRFRIRQLVRIDHI---PDLPLPKPLISYIRKFYY 598
           567899*********************998...*************99976 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MVFRNVGRPP EEEDVEAAPE PGPSELLCPR HRCALDPKAL PPGLALERTW GPAAGLEAQL 60
AALGLGQPAG PGVKTVGGGC CPCPCPPQPP PPQPQPPAVA PQAGEDPTET SDALLVLEGL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TCCTATCTCT GTTGCCTACT GGGTGAACTT GGGCAANNNN NNNNNNNNNN NNNNNNCCCC 60
GAGCCAGGCC CGCCGCCGCC GCCCCCGGGC CATGGCCCCC CGCCGCCACC CTTCCTCGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000980--SH2
IPR028423--SOCS7
IPR001496--SOCS_box

PROSITE

PS50001--SH2
PS50225--SOCS

Pfam

PF00017--SH2
PF07525--SOCS_box

SMART

SM00252--SH2
SM00253--SOCS
SM00969--SOCS_box

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0004860--F:protein kinase inhibitor activity
GO:0019221--P:cytokine-mediated signaling pathway
GO:0045444--P:fat cell differentiation
GO:0008286--P:insulin receptor signaling pathway
GO:0035556--P:intracellular signal transduction
GO:0021819--P:layer formation in cerebral cortex
GO:0046426--P:negative regulation of JAK-STAT cascade
GO:0006469--P:negative regulation of protein kinase activity
GO:0016567--P:protein ubiquitination
GO:0021942--P:radial glia guided migration of Purkinje cell

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001668	Ailuropoda melanoleuca	83.56	0.00e+00	642.00
IUUC-Apl-003277	Anas platyrhynchos	91.78	8.00e-73	265.00
IUUC-Aca-004639	Anolis carolinensis	97.28	4.00e-108	383.00
IUUC-Ame-011301	Astyanax mexicanus	62.44	2.00e-123	435.00
IUUC-Bta-013483	Bos taurus	89.63	0.00e+00	717.00
IUUC-Cja-019765	Callithrix jacchus	100.00	6.00e-164	569.00
IUUC-Cfa-020109	Canis familiaris	87.94	0.00e+00	630.00
IUUC-Cpo-021555	Cavia porcellus	86.05	3.00e-172	597.00
IUUC-Csa-023580	Chlorocebus sabaeus	92.19	0.00e+00	706.00
IUUC-Cho-024431	Choloepus hoffmanni	99.21	4.00e-72	265.00
IUUC-Dre-028183	Danio rerio	63.12	3.00e-132	466.00
IUUC-Dno-028858	Dasypus novemcinctus	88.18	0.00e+00	700.00
IUUC-Dor-031071	Dipodomys ordii	79.56	1.00e-114	405.00
IUUC-Dme-031876	Drosophila melanogaster	43.65	3.00e-43	170.00
IUUC-Ete-032928	Echinops telfairi	77.34	2.00e-98	352.00
IUUC-Eca-033250	Equus caballus	84.13	6.00e-171	593.00
IUUC-Eeu-034946	Erinaceus europaeus	73.14	2.00e-46	179.00
IUUC-Fca-036589	Felis catus	85.96	3.00e-180	624.00
IUUC-Fal-037316	Ficedula albicollis	93.07	4.00e-112	397.00
IUUC-Gmo-038552	Gadus morhua	91.26	2.00e-53	201.00
IUUC-Gga-041248	Gallus gallus	96.76	6.00e-108	382.00
IUUC-Gac-041469	Gasterosteus aculeatus	83.47	2.00e-56	211.00
IUUC-Ggo-045282	Gorilla gorilla	99.69	4.00e-163	566.00
IUUC-Hsa-045926	Homo sapiens	92.03	0.00e+00	708.00
IUUC-Itr-048411	Ictidomys tridecemlineatus	88.17	4.00e-159	554.00
IUUC-Lch-049768	Latimeria chalumnae	65.18	1.00e-146	513.00
IUUC-Loc-051949	Lepisosteus oculatus	76.58	3.00e-120	426.00
IUUC-Laf-053410	Loxodonta africana	87.48	0.00e+00	700.00
IUUC-Meu-056773	Macropus eugenii	80.19	6.00e-107	380.00
IUUC-Mmr-060927	Microcebus murinus	90.10	0.00e+00	696.00
IUUC-Mdo-061892	Monodelphis domestica	81.02	3.00e-170	592.00
IUUC-Mmu-064246	Mus musculus	87.40	0.00e+00	697.00
IUUC-Mpu-065995	Mustela putorius furo	87.36	4.00e-178	617.00
IUUC-Mlu-067526	Myotis lucifugus	87.38	0.00e+00	707.00
IUUC-Nle-069317	Nomascus leucogenys	84.92	1.00e-164	572.00
IUUC-Ont-072258	Oreochromis niloticus	58.97	2.00e-112	399.00
IUUC-Oan-073703	Ornithorhynchus anatinus	80.49	2.00e-36	143.00
IUUC-Ocu-074577	Oryctolagus cuniculus	83.54	0.00e+00	723.00
IUUC-Oga-088426	Otolemur garnettii	89.14	0.00e+00	685.00
IUUC-Oar-089407	Ovis aries	88.36	0.00e+00	644.00
IUUC-Ptr-091327	Pan troglodytes	88.89	7.00e-178	616.00
IUUC-Pan-092064	Papio anubis	88.84	0.00e+00	629.00
IUUC-Psi-093834	Pelodiscus sinensis	94.36	9.00e-154	535.00
IUUC-Pfo-097100	Poecilia formosa	56.53	1.00e-110	394.00
IUUC-Pab-097695	Pongo abelii	83.87	0.00e+00	675.00
IUUC-Pca-100569	Procavia capensis	80.52	5.00e-164	570.00
IUUC-Pva-102784	Pteropus vampyrus	88.82	0.00e+00	690.00
IUUC-Ptt-103775	Puccinia triticina	38.46	1.80e+00	28.10
IUUC-Rno-105485	Rattus norvegicus	88.66	0.00e+00	699.00
IUUC-Sha-106720	Sarcophilus harrisii	83.53	2.00e-166	578.00
IUUC-Sar-112975	Sorex araneus	84.59	2.00e-128	451.00
IUUC-Ssc-116369	Sus scrofa	90.27	0.00e+00	713.00
IUUC-Tgu-116867	Taeniopygia guttata	86.52	7.00e-125	439.00
IUUC-Tru-117562	Takifugu rubripes	77.53	2.00e-100	359.00
IUUC-Tsy-118999	Tarsius syrichta	93.71	1.00e-146	511.00
IUUC-Tni-120793	Tetraodon nigroviridis	61.42	9.00e-123	433.00
IUUC-Tbe-127671	Tupaia belangeri	99.07	1.00e-128	452.00
IUUC-Ttr-128491	Tursiops truncatus	75.19	4.00e-125	441.00
IUUC-Vpa-130104	Vicugna pacos	80.74	5.00e-169	587.00
IUUC-Xtr-132507	Xenopus tropicalis	71.66	1.00e-137	483.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence