iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052334

Ensembl Protein ID

ENSLOCP00000008516.1

UniProt Accession

W5MJF7; W5MJF7_LEPOC

Genbank Protein ID

ENSLOCP00000008516

Protein Name

Inhibitor of growth protein

Genbank Nucleotide ID

AHAT01034837

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000007026.1	ENSLOCT00000008526.1	ENSLOCP00000008516.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.80e-10	38.8	201	248

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C++ + +e  ++ C++  C+ ewfH+aC++l+   ++p+ + w+Cp+C++
   Q: 201  TYC-LCHQVSYGE--MIGCDNtdCSiEWFHFACVGLT---TKPRGK-WYCPRCSQ 248
           69*.*******99..*****999999***********...899996.******97 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MAAGMYLEHY LDSNSYCGFP VEAQFGKDIM RTLSPPSSDL KGQIDGLARE YTANARTLSS 60
EQKLSLLRQI QQSYSKCKEF GDDKVQLAMQ TYEMAGENSV LGTLSELMRS VPFTVTVTVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGGCTG GGATGTATTT GGAGCATTAT TTGGACAGTA AGTGATAACT ATCATTATCC 60
CTTTCTGAGA AAATCGATTA TTTGGAAGTA TCCCTCGGAT ACTTAATGCA GAAGAAAAAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028647--ING4
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016573--P:histone acetylation
GO:0008285--P:negative regulation of cell proliferation
GO:0043065--P:positive regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ame-011133	Astyanax mexicanus	73.91	5.00e-107	380.00
IUUC-Dre-028264	Danio rerio	73.12	3.00e-105	374.00
IUUC-Dor-031136	Dipodomys ordii	58.51	3.00e-67	247.00
IUUC-Gmo-038982	Gadus morhua	70.47	4.00e-101	360.00
IUUC-Gac-042184	Gasterosteus aculeatus	70.68	5.00e-100	356.00
IUUC-Hvu-047046	Hordeum vulgare	32.70	1.00e-27	116.00
IUUC-Ont-072446	Oreochromis niloticus	68.38	1.00e-97	349.00
IUUC-Ola-086429	Oryzias latipes	67.59	2.00e-95	341.00
IUUC-Pfo-096617	Poecilia formosa	70.36	2.00e-101	361.00
IUUC-Sre-115124	Sporisorium reilianum	59.32	4.00e-22	99.80
IUUC-Tru-118253	Takifugu rubripes	70.20	6.00e-101	359.00
IUUC-Ttr-128300	Tursiops truncatus	81.98	5.00e-52	197.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence