iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-070098

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01099418

Gene Name

TRAF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000002954.2	ENSNLET00000003788.2	ENSNLEP00000003611.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.30e-06	28.0	18	56

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPl 44
           C++C  ++++++ v  CgH f+ +Clq +     +s + f+CP 
   Q: 18   CPLCGKPMREPVQVSTCGHRFCDTCLQEF-----LSEGVFKCPE 56
           ********99888888**********999.....89*******6 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSEG VFKCPEDQLP 60
LDYAKXXXDP ELEVQVLGLP IRCIHSEEGC RWSGPLRHLQ GHLNTCSFNV IPCPNRCPMK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCGGGCTT CACAGCCGAG CCCTGGCAGC GACCGCCAGT CGGCGCCGCC CGGAGCCGGG 60
AGCACCGCTC CAGCGAGGCG CGGGCTGTGG GGCCGCCGCG TGCCTGGCCC CGCTCGCCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027138--TRAF4
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0046330--P:positive regulation of JNK cascade
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0042981--P:regulation of apoptotic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001287	Ailuropoda melanoleuca	95.10	0.00e+00	885.00
IUUC-Ame-011530	Astyanax mexicanus	76.60	0.00e+00	765.00
IUUC-Bta-013582	Bos taurus	96.60	0.00e+00	907.00
IUUC-Cja-019883	Callithrix jacchus	94.79	1.00e-51	194.00
IUUC-Cfa-020133	Canis familiaris	90.43	0.00e+00	835.00
IUUC-Cpo-022021	Cavia porcellus	97.02	0.00e+00	913.00
IUUC-Csa-023199	Chlorocebus sabaeus	97.87	0.00e+00	919.00
IUUC-Dre-028193	Danio rerio	75.74	0.00e+00	760.00
IUUC-Dno-028917	Dasypus novemcinctus	97.02	0.00e+00	911.00
IUUC-Ete-032433	Echinops telfairi	96.38	0.00e+00	908.00
IUUC-Fca-036155	Felis catus	96.60	0.00e+00	908.00
IUUC-Gmo-038860	Gadus morhua	76.60	0.00e+00	763.00
IUUC-Gga-041052	Gallus gallus	79.79	0.00e+00	815.00
IUUC-Gac-041489	Gasterosteus aculeatus	76.81	0.00e+00	763.00
IUUC-Ggo-044996	Gorilla gorilla	98.30	0.00e+00	922.00
IUUC-Hsa-046252	Homo sapiens	98.51	0.00e+00	924.00
IUUC-Hvu-047127	Hordeum vulgare	36.71	2.00e-07	50.10
IUUC-Itr-048232	Ictidomys tridecemlineatus	97.45	0.00e+00	915.00
IUUC-Kpa-049340	Komagataella pastoris	25.56	6.00e-14	72.00
IUUC-Lpe-051100	Leersia perrieri	38.57	8.00e-08	51.20
IUUC-Loc-052312	Lepisosteus oculatus	76.65	0.00e+00	762.00
IUUC-Laf-054376	Loxodonta africana	97.02	0.00e+00	910.00
IUUC-Mcc-055684	Macaca mulatta	97.87	0.00e+00	919.00
IUUC-Mmr-061198	Microcebus murinus	97.45	0.00e+00	914.00
IUUC-Mdo-062585	Monodelphis domestica	85.53	0.00e+00	817.00
IUUC-Mmu-064303	Mus musculus	95.53	0.00e+00	902.00
IUUC-Mpu-066854	Mustela putorius furo	96.17	0.00e+00	904.00
IUUC-Ont-071518	Oreochromis niloticus	76.55	0.00e+00	762.00
IUUC-Ocu-073841	Oryctolagus cuniculus	97.23	0.00e+00	913.00
IUUC-Ola-086674	Oryzias latipes	76.33	0.00e+00	759.00
IUUC-Oga-088510	Otolemur garnettii	97.02	0.00e+00	912.00
IUUC-Oar-089225	Ovis aries	93.40	0.00e+00	868.00
IUUC-Pan-092725	Papio anubis	97.87	0.00e+00	919.00
IUUC-Pfo-096341	Poecilia formosa	76.33	0.00e+00	763.00
IUUC-Pva-103131	Pteropus vampyrus	97.33	3.00e-141	494.00
IUUC-Rno-105996	Rattus norvegicus	95.74	0.00e+00	902.00
IUUC-Sly-111800	Solanum lycopersicum	29.17	2.00e-05	45.80
IUUC-Tru-117602	Takifugu rubripes	76.60	0.00e+00	765.00
IUUC-Tur-126067	Triticum urartu	35.51	1.00e-08	53.90

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence