iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCJAG00000011179.2	ENSCJAT00000021795.1	ENSCJAP00000020621.1
ENSCJAG00000011179.2	ENSCJAT00000021777.2	ENSCJAP00000020602.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	97.01	0.00e+00	1014.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Callithrix jacchus

Protein Sequence
(Fasta)

MAAASVTPPG SLELLQPGFS KTLLGTKLEA KYLCSACRNV LRRPFQAQCG HRYCSFCLAS 60
ILSSGPQNCA ACVHEGIYEE GISILESSSA FPDNAARREV ESLPAVCPSD GCTWKGTLKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACCAGCTT CCTCTGGAGG CTGCAGCACA GGCCTGACCT TCGAATGTCT GAAAAACAGA 60
GGCCAGCTCT TGGTGTGAGC AAGTGGACTG TGGCTATCTG AGGTGGGCAC TTCCCTTGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0675--Receptor
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

KEGG

cjc:100404226

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	86.04	0.00e+00	908.00
IUUC-Apl-004202	Anas platyrhynchos	74.86	0.00e+00	834.00
IUUC-Aca-005029	Anolis carolinensis	58.47	9.00e-149	520.00
IUUC-Ame-011841	Astyanax mexicanus	54.88	0.00e+00	638.00
IUUC-Bta-013180	Bos taurus	85.55	0.00e+00	890.00
IUUC-Cfa-021205	Canis familiaris	90.22	0.00e+00	921.00
IUUC-Cpo-021346	Cavia porcellus	88.62	0.00e+00	922.00
IUUC-Csa-023809	Chlorocebus sabaeus	95.52	0.00e+00	889.00
IUUC-Dre-027669	Danio rerio	58.33	7.00e-178	616.00
IUUC-Dno-029458	Dasypus novemcinctus	82.79	0.00e+00	887.00
IUUC-Dor-030338	Dipodomys ordii	86.43	0.00e+00	835.00
IUUC-Eca-034401	Equus caballus	90.10	0.00e+00	944.00
IUUC-Eeu-034668	Erinaceus europaeus	71.34	4.00e-108	385.00
IUUC-Fca-036057	Felis catus	86.62	0.00e+00	930.00
IUUC-Fal-037560	Ficedula albicollis	71.46	0.00e+00	735.00
IUUC-Gmo-038964	Gadus morhua	62.70	0.00e+00	663.00
IUUC-Gga-040425	Gallus gallus	74.95	0.00e+00	827.00
IUUC-Gac-041908	Gasterosteus aculeatus	63.96	0.00e+00	679.00
IUUC-Ggo-044606	Gorilla gorilla	89.62	0.00e+00	925.00
IUUC-Hsa-046952	Homo sapiens	97.01	0.00e+00	1014.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	76.25	0.00e+00	780.00
IUUC-Lch-049571	Latimeria chalumnae	58.97	0.00e+00	695.00
IUUC-Loc-051973	Lepisosteus oculatus	62.98	0.00e+00	637.00
IUUC-Laf-053815	Loxodonta africana	83.10	0.00e+00	848.00
IUUC-Mcc-054888	Macaca mulatta	96.81	0.00e+00	1010.00
IUUC-Meu-056547	Macropus eugenii	73.29	0.00e+00	665.00
IUUC-Mga-059819	Meleagris gallopavo	74.85	0.00e+00	784.00
IUUC-Mdo-062570	Monodelphis domestica	81.47	0.00e+00	848.00
IUUC-Mmu-063133	Mus musculus	86.43	0.00e+00	874.00
IUUC-Mac-064547	Musa acuminata	32.65	4.00e-06	47.40
IUUC-Mpu-065802	Mustela putorius furo	87.30	0.00e+00	926.00
IUUC-Nle-070155	Nomascus leucogenys	98.20	0.00e+00	1024.00
IUUC-Opr-070856	Ochotona princeps	84.65	4.00e-112	398.00
IUUC-Ont-071930	Oreochromis niloticus	63.98	0.00e+00	709.00
IUUC-Ola-087397	Oryzias latipes	60.71	0.00e+00	687.00
IUUC-Oga-088109	Otolemur garnettii	94.61	0.00e+00	993.00
IUUC-Oar-090310	Ovis aries	76.67	0.00e+00	795.00
IUUC-Ptr-090643	Pan troglodytes	97.60	0.00e+00	1020.00
IUUC-Pan-091933	Papio anubis	97.41	0.00e+00	1013.00
IUUC-Psi-093681	Pelodiscus sinensis	72.94	0.00e+00	782.00
IUUC-Pfo-096148	Poecilia formosa	60.52	0.00e+00	694.00
IUUC-Pab-098631	Pongo abelii	97.41	0.00e+00	1021.00
IUUC-Pca-100582	Procavia capensis	65.89	3.00e-88	318.00
IUUC-Pva-102396	Pteropus vampyrus	74.45	0.00e+00	740.00
IUUC-Rno-106120	Rattus norvegicus	84.03	0.00e+00	861.00
IUUC-Sha-106493	Sarcophilus harrisii	81.67	0.00e+00	874.00
IUUC-Sit-110103	Setaria italica	26.27	5.00e-05	43.90
IUUC-Sar-113570	Sorex araneus	93.92	2.00e-100	358.00
IUUC-Ssc-115843	Sus scrofa	84.62	0.00e+00	914.00
IUUC-Tgu-117144	Taeniopygia guttata	69.88	0.00e+00	706.00
IUUC-Tru-117853	Takifugu rubripes	61.38	0.00e+00	687.00
IUUC-Tni-120256	Tetraodon nigroviridis	64.87	0.00e+00	718.00
IUUC-Tur-126325	Triticum urartu	26.27	2.00e-05	45.10
IUUC-Tbe-127943	Tupaia belangeri	65.99	1.00e-101	362.00
IUUC-Ttr-129246	Tursiops truncatus	88.29	0.00e+00	901.00
IUUC-Xtr-132279	Xenopus tropicalis	60.00	2.00e-174	605.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence