iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSSCG00000005838.3	ENSSSCT00000034674.1	ENSSSCP00000030488.1
ENSSSCG00000005838.3	ENSSSCT00000006417.2	ENSSSCP00000006248.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	85.19	0.00e+00	918.00	IUUC-Hsa-046952

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Sus scrofa

Protein Sequence
(Fasta)

WLSGLGLGGA VAPMAAASVT PPGSLDLLQP GFSKTLLGTK LEDKYLCSAC RNVLRRPFQA 60
QCGHRYCSYC LSNILSSGPQ NCAACVHEGI YEEGVSILES SSAFPDNAAR REVESLPAVC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCTCTCAG GTCTGCAGCA GGTGGGGCTA GCCTGTCCCC AGGCTCCAGA GGGCACTGAG 60
AGCCCGCGCT CCCTTTCCTG AGCCCCTCGT CCTGAGTGCG CAGACCCTGG TGGCCGCCGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0732--Signal
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR002083--MATH/TRAF_dom
IPR012227--TNF_rcpt--assoc_TRAF
IPR008974--TRAF-like
IPR027133--TRAF2
IPR032070--TRAF_BIRC3-bd
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS
IPR001293--Znf_TRAF

PROSITE

PS50144--MATH
PS00518--ZF_RING_1
PS50089--ZF_RING_2
PS50145--ZF_TRAF

Pfam

PF16673--TRAF_BIRC3_bd
PF00097--zf-C3HC4
PF02176--zf-TRAF

SMART

SM00061--MATH
SM00184--RING

Gene Ontology

GO:1990597--C:AIP1-IRE1 complex
GO:0035631--C:CD40 receptor complex
GO:0009898--C:cytoplasmic side of plasma membrane
GO:0005829--C:cytosol
GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:0045121--C:membrane raft
GO:0097057--C:TRAF2-GSTP1 complex
GO:0000151--C:ubiquitin ligase complex
GO:0012506--C:vesicle membrane
GO:0046625--F:sphingolipid binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007250--P:activation of NF-kappaB-inducing kinase activity
GO:0043623--P:cellular protein complex assembly
GO:0071732--P:cellular response to nitric oxide
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:1903721--P:positive regulation of I-kappaB phosphorylation
GO:0032743--P:positive regulation of interleukin-2 production
GO:0043507--P:positive regulation of JUN kinase activity
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0090073--P:positive regulation of protein homodimerization activity
GO:0002726--P:positive regulation of T cell cytokine production
GO:1903265--P:positive regulation of tumor necrosis factor-mediated signaling pathway
GO:0097300--P:programmed necrotic cell death
GO:0051865--P:protein autoubiquitination
GO:0030163--P:protein catabolic process
GO:0070207--P:protein homotrimerization
GO:0070534--P:protein K63-linked ubiquitination
GO:0051023--P:regulation of immunoglobulin secretion
GO:0033209--P:tumor necrosis factor-mediated signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002344	Ailuropoda melanoleuca	89.10	0.00e+00	932.00
IUUC-Apl-004202	Anas platyrhynchos	71.40	0.00e+00	810.00
IUUC-Aca-005029	Anolis carolinensis	53.98	2.00e-140	492.00
IUUC-Ame-011841	Astyanax mexicanus	57.69	0.00e+00	693.00
IUUC-Bta-013180	Bos taurus	88.57	0.00e+00	920.00
IUUC-Cja-019813	Callithrix jacchus	85.00	0.00e+00	914.00
IUUC-Cfa-021205	Canis familiaris	87.12	0.00e+00	907.00
IUUC-Cpo-021346	Cavia porcellus	84.04	0.00e+00	894.00
IUUC-Csa-023809	Chlorocebus sabaeus	83.98	0.00e+00	800.00
IUUC-Dre-027669	Danio rerio	55.43	5.00e-177	613.00
IUUC-Dno-029458	Dasypus novemcinctus	81.03	0.00e+00	874.00
IUUC-Dor-030338	Dipodomys ordii	82.34	0.00e+00	811.00
IUUC-Eca-034401	Equus caballus	89.04	0.00e+00	954.00
IUUC-Eeu-034668	Erinaceus europaeus	93.42	9.00e-83	300.00
IUUC-Fca-036057	Felis catus	88.97	0.00e+00	958.00
IUUC-Fal-037560	Ficedula albicollis	69.22	0.00e+00	713.00
IUUC-Gmo-038964	Gadus morhua	59.77	0.00e+00	656.00
IUUC-Gga-040425	Gallus gallus	72.40	0.00e+00	809.00
IUUC-Gac-041908	Gasterosteus aculeatus	60.99	0.00e+00	668.00
IUUC-Ggo-044606	Gorilla gorilla	78.65	0.00e+00	827.00
IUUC-Hsa-046952	Homo sapiens	85.38	0.00e+00	917.00
IUUC-Itr-049016	Ictidomys tridecemlineatus	71.14	0.00e+00	736.00
IUUC-Lch-049571	Latimeria chalumnae	58.28	0.00e+00	694.00
IUUC-Loc-051973	Lepisosteus oculatus	61.31	0.00e+00	627.00
IUUC-Laf-053815	Loxodonta africana	82.50	0.00e+00	857.00
IUUC-Mcc-054888	Macaca mulatta	85.19	0.00e+00	912.00
IUUC-Meu-056547	Macropus eugenii	67.83	0.00e+00	634.00
IUUC-Mga-059819	Meleagris gallopavo	70.35	0.00e+00	761.00
IUUC-Mdo-062570	Monodelphis domestica	77.33	0.00e+00	840.00
IUUC-Mmu-063133	Mus musculus	82.12	0.00e+00	845.00
IUUC-Mac-064547	Musa acuminata	30.51	5.00e-06	47.00
IUUC-Mpu-065802	Mustela putorius furo	88.35	0.00e+00	936.00
IUUC-Nle-070155	Nomascus leucogenys	85.77	0.00e+00	923.00
IUUC-Opr-070856	Ochotona princeps	76.52	2.00e-107	382.00
IUUC-Ont-071930	Oreochromis niloticus	62.69	0.00e+00	711.00
IUUC-Ola-087397	Oryzias latipes	60.37	0.00e+00	689.00
IUUC-Oga-088109	Otolemur garnettii	84.81	0.00e+00	910.00
IUUC-Oar-090310	Ovis aries	79.96	0.00e+00	814.00
IUUC-Ptr-090643	Pan troglodytes	85.77	0.00e+00	920.00
IUUC-Pan-091933	Papio anubis	85.77	0.00e+00	914.00
IUUC-Psi-093681	Pelodiscus sinensis	72.16	0.00e+00	775.00
IUUC-Pfo-096148	Poecilia formosa	60.56	0.00e+00	697.00
IUUC-Pab-098631	Pongo abelii	84.40	0.00e+00	926.00
IUUC-Pca-100582	Procavia capensis	59.42	1.00e-81	296.00
IUUC-Pva-102396	Pteropus vampyrus	72.50	0.00e+00	739.00
IUUC-Rno-106120	Rattus norvegicus	80.96	0.00e+00	835.00
IUUC-Sha-106493	Sarcophilus harrisii	77.69	0.00e+00	863.00
IUUC-Sar-113570	Sorex araneus	90.06	7.00e-97	346.00
IUUC-Tgu-117144	Taeniopygia guttata	65.65	0.00e+00	687.00
IUUC-Tru-117853	Takifugu rubripes	60.84	0.00e+00	686.00
IUUC-Tni-120256	Tetraodon nigroviridis	62.31	0.00e+00	707.00
IUUC-Tbe-127943	Tupaia belangeri	62.03	5.00e-98	350.00
IUUC-Ttr-129246	Tursiops truncatus	87.31	0.00e+00	902.00
IUUC-Xtr-132279	Xenopus tropicalis	57.23	2.00e-170	592.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence