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Tag Content
iUUCD ID IUUC-Sha-106851
Ensembl Protein ID ENSSHAP00000002745.1
UniProt Accession G3VHU1; G3VHU1_SARHA
Genbank Protein ID ENSSHAP00000002745
Protein Name Uncharacterized protein
Genbank Nucleotide ID AEFK01104458
Gene Name ITSN1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSSHAG00000002428.1 ENSSHAT00000002776.1 ENSSHAP00000002745.1
ENSSHAG00000002428.1 ENSSHAT00000002777.1 ENSSHAP00000002746.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 2.80e-66 219.5 1160 1212
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v+ +ydy+aqnddeL ++kG ++ v+  +++d +W+kg  e +g+ GlfP+n+v+ 
   Q: 1160 QVIGMYDYTAQNDDELAFNKGQIINVL--NKEDPDWWKG--EVNGQVGLFPSNYVKM 1212
           46779**********************..8889******..9*************85 PP
   
Organism Sarcophilus harrisii
Protein Sequence
(Fasta)
MAQFPTSFGG SLDIWAITVE ERTKHDQQFH SLKPTSGFIT GDQARNFFFQ SGLPQPVLAQ 60
IWALADMNND GRMDQIEFSI AMKLIKLKLQ GYQLPATLPP VMKQQPVAIS GAPTFGIGGI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sha-106851|UBD,SH3|Sarcophilus harrisii
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GCTTCTACTA GCGAGCTAAA AGTGACAGAA CCATGGCTCA ATTTCCGACA TCTTTTGGTG 60
GTAAGTTTTC ACGTTTTTTT CTTTAGCAAG TTGCAAAGTG CATTGACGGA AAGGTCTGCA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sha-106851|UBD,SH3|Sarcophilus harrisii
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0106--Calcium
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
Interpro

IPR000008--C2_dom
IPR000219--DH-domain
IPR011992--EF-hand-dom_pair
IPR018247--EF_Hand_1_Ca_BS
IPR002048--EF_hand_dom
IPR000261--EH_dom
IPR001331--GDS_CDC24_CS
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS00741--DH_1
PS50010--DH_2
PS00018--EF_HAND_1
PS50222--EF_HAND_2
PS50031--EH
PS50003--PH_DOMAIN
PS50002--SH3
Pfam

PF00168--C2
PF12763--EF-hand_4
PF16652--PH_13
PF00621--RhoGEF
PF00018--SH3_1
PF14604--SH3_9
PRINTS

PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00054--EFh
SM00027--EH
SM00233--PH
SM00325--RhoGEF
SM00326--SH3
Gene Ontology

GO:0005905--C:clathrin-coated pit
GO:0030139--C:endocytic vesicle
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0005509--F:calcium ion binding
GO:0019209--F:kinase activator activity
GO:0005089--F:Rho guanyl-nucleotide exchange factor activity
GO:0043524--P:negative regulation of neuron apoptotic process
GO:0051897--P:positive regulation of protein kinase B signaling
GO:0035023--P:regulation of Rho protein signal transduction
GO:0007264--P:small GTPase mediated signal transduction
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000722 Aegilops tauschii 41.67 3.00e-14 74.70
IUUC-Aml-001218 Ailuropoda melanoleuca 90.96 0.00e+00 2292.00
IUUC-Apl-003335 Anas platyrhynchos 90.74 0.00e+00 2217.00
IUUC-Aca-005130 Anolis carolinensis 88.90 0.00e+00 2195.00
IUUC-Ago-007935 Ashbya gossypii 35.07 2.00e-14 73.90
IUUC-Ame-011878 Astyanax mexicanus 76.20 0.00e+00 1910.00
IUUC-Bta-012863 Bos taurus 90.48 0.00e+00 2256.00
IUUC-Bdi-014016 Brachypodium distachyon 29.53 1.00e-14 75.90
IUUC-Bol-015187 Brassica oleracea 37.66 1.00e-10 61.60
IUUC-Bra-017706 Brassica rapa 35.83 1.00e-12 68.90
IUUC-Cel-018490 Caenorhabditis elegans 33.97 1.00e-43 172.00
IUUC-Cja-019012 Callithrix jacchus 91.44 0.00e+00 2278.00
IUUC-Cfa-020272 Canis familiaris 91.36 0.00e+00 2303.00
IUUC-Cpo-021352 Cavia porcellus 84.73 0.00e+00 2706.00
IUUC-Csa-023122 Chlorocebus sabaeus 65.38 0.00e+00 1282.00
IUUC-Cho-024969 Choloepus hoffmanni 80.28 0.00e+00 1799.00
IUUC-Cin-025435 Ciona intestinalis 45.71 0.00e+00 974.00
IUUC-Csv-026290 Ciona savignyi 58.07 0.00e+00 787.00
IUUC-Cne-026918 Cryptococcus neoformans 33.55 5.00e-39 157.00
IUUC-Dre-028623 Danio rerio 76.00 0.00e+00 1930.00
IUUC-Dno-030044 Dasypus novemcinctus 90.61 0.00e+00 2265.00
IUUC-Dor-030272 Dipodomys ordii 84.32 0.00e+00 1980.00
IUUC-Dme-032099 Drosophila melanogaster 53.46 5.00e-44 173.00
IUUC-Ete-032927 Echinops telfairi 96.39 0.00e+00 1023.00
IUUC-Eca-033469 Equus caballus 91.36 0.00e+00 2262.00
IUUC-Eeu-034977 Erinaceus europaeus 85.74 0.00e+00 1029.00
IUUC-Fca-036419 Felis catus 91.44 0.00e+00 2264.00
IUUC-Fal-037236 Ficedula albicollis 88.28 0.00e+00 2205.00
IUUC-Gmo-039632 Gadus morhua 68.75 0.00e+00 1654.00
IUUC-Gga-040835 Gallus gallus 88.41 0.00e+00 2184.00
IUUC-Gac-041948 Gasterosteus aculeatus 71.31 0.00e+00 1786.00
IUUC-Ggo-045405 Gorilla gorilla 55.84 0.00e+00 1631.00
IUUC-Hsa-045699 Homo sapiens 91.83 0.00e+00 2313.00
IUUC-Hvu-047530 Hordeum vulgare 31.18 4.00e-14 73.20
IUUC-Itr-048773 Ictidomys tridecemlineatus 89.00 0.00e+00 2216.00
IUUC-Lch-050502 Latimeria chalumnae 78.89 0.00e+00 1624.00
IUUC-Lpe-051250 Leersia perrieri 41.67 3.00e-14 74.30
IUUC-Loc-052613 Lepisosteus oculatus 79.30 0.00e+00 1957.00
IUUC-Laf-053608 Loxodonta africana 90.05 0.00e+00 2277.00
IUUC-Mcc-055720 Macaca mulatta 91.28 0.00e+00 2290.00
IUUC-Meu-056445 Macropus eugenii 88.84 0.00e+00 1767.00
IUUC-Mtr-057705 Medicago truncatula 36.27 2.00e-12 68.20
IUUC-Mla-059128 Melampsora laricipopulina 29.91 1.00e-38 156.00
IUUC-Mga-059997 Meleagris gallopavo 58.22 0.00e+00 1438.00
IUUC-Mvi-060268 Microbotryum violaceum 29.40 2.00e-43 171.00
IUUC-Mmr-061258 Microcebus murinus 91.99 0.00e+00 2272.00
IUUC-Mdo-062019 Monodelphis domestica 97.22 0.00e+00 2338.00
IUUC-Mmu-063885 Mus musculus 90.09 0.00e+00 2276.00
IUUC-Mpu-066431 Mustela putorius furo 64.97 0.00e+00 1290.00
IUUC-Mlu-068190 Myotis lucifugus 58.27 0.00e+00 1392.00
IUUC-Nle-070116 Nomascus leucogenys 61.27 0.00e+00 935.00
IUUC-Opr-070441 Ochotona princeps 85.15 0.00e+00 1996.00
IUUC-Ont-071752 Oreochromis niloticus 72.57 0.00e+00 1785.00
IUUC-Oan-073390 Ornithorhynchus anatinus 87.79 0.00e+00 2139.00
IUUC-Ocu-073753 Oryctolagus cuniculus 89.00 0.00e+00 2854.00
IUUC-Ogu-078849 Oryza glumaepatula 41.67 3.00e-14 74.30
IUUC-Olo-080259 Oryza longistaminata 41.67 2.00e-14 74.70
IUUC-Ome-081199 Oryza meridionalis 41.67 3.00e-14 74.30
IUUC-Oni-082167 Oryza nivara 41.67 5.00e-14 73.60
IUUC-Oru-084541 Oryza rufipogon 41.67 5.00e-14 73.60
IUUC-Ola-086482 Oryzias latipes 55.47 0.00e+00 1108.00
IUUC-Olu-087698 Ostreococcus lucimarinus 28.75 2.00e-17 84.00
IUUC-Oga-088602 Otolemur garnettii 91.83 0.00e+00 2282.00
IUUC-Oar-090195 Ovis aries 90.64 0.00e+00 2264.00
IUUC-Ptr-091363 Pan troglodytes 91.91 0.00e+00 2315.00
IUUC-Pan-092385 Papio anubis 91.70 0.00e+00 2303.00
IUUC-Psi-093136 Pelodiscus sinensis 63.77 0.00e+00 1289.00
IUUC-Pfo-097486 Poecilia formosa 74.29 0.00e+00 1821.00
IUUC-Pab-098281 Pongo abelii 80.98 0.00e+00 1932.00
IUUC-Pca-100270 Procavia capensis 74.47 0.00e+00 1268.00
IUUC-Pva-102335 Pteropus vampyrus 89.06 0.00e+00 2203.00
IUUC-Pgr-103473 Puccinia graminis 28.99 2.00e-36 149.00
IUUC-Ptt-103973 Puccinia triticina 24.01 7.00e-26 114.00
IUUC-Rno-106122 Rattus norvegicus 89.00 0.00e+00 2244.00
IUUC-Sja-107736 Schizosaccharomyces japonicus 26.63 6.00e-18 86.30
IUUC-Smo-108995 Selaginella moellendorffii 36.62 4.00e-08 53.10
IUUC-Sit-110414 Setaria italica 40.48 4.00e-14 73.90
IUUC-Sbi-114170 Sorghum bicolor 38.89 3.00e-14 74.30
IUUC-Sre-115028 Sporisorium reilianum 34.13 6.00e-32 134.00
IUUC-Ssc-115562 Sus scrofa 61.04 0.00e+00 1159.00
IUUC-Tgu-117028 Taeniopygia guttata 89.32 0.00e+00 2236.00
IUUC-Tru-117789 Takifugu rubripes 76.02 0.00e+00 1850.00
IUUC-Tsy-119039 Tarsius syrichta 92.31 0.00e+00 1381.00
IUUC-Tni-119952 Tetraodon nigroviridis 74.26 0.00e+00 1714.00
IUUC-Tae-123242 Triticum aestivum 41.67 4.00e-14 73.60
IUUC-Tur-126623 Triticum urartu 40.00 4.00e-14 73.90
IUUC-Tbe-127754 Tupaia belangeri 79.74 0.00e+00 1598.00
IUUC-Ttr-129178 Tursiops truncatus 90.73 0.00e+00 2259.00
IUUC-Uma-129456 Ustilago maydis 31.01 8.00e-32 133.00
IUUC-Vpa-130687 Vicugna pacos 84.32 0.00e+00 1061.00
IUUC-Xtr-132905 Xenopus tropicalis 86.39 0.00e+00 2158.00
Created Date 25-Jun-2017

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