iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Csa-024141

Ensembl Protein ID

ENSCSAP00000018411.1

UniProt Accession

A0A0D9SC22; A0A0D9SC22_CHLSB

Genbank Protein ID

ENSCSAP00000018411

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AQIB01075930

Gene Name

TRIM59

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCSAG00000018892.1	ENSCSAT00000018982.1	ENSCSAP00000018411.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.90e-09	37.9	10	60
E3 activity/RING/U-box	2.30e-06	27.5	6	89

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENI----LQASGNFYiwrplriplkCPNCR 60
           **********.***************999....567777766666666777****8 PP

E3 activity/RING/U-box

   S: 4    eeflCpIslelMrdPvvlpsGitydrssIekwlasggk...........tcPvtrqpl.....teedlvPnltlrrliqawcee 71
           ee+ CpI + +++dP vlp+ +t+ r+++e  l+ +g+           +cP +r+ +       e+l  n +lr++i+++ +e
   Q: 6    EELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNfyiwrplriplKCPNCRSIIeiaptGIESLPVNFALRAIIEKYQQE 89
           7999*****************************999999**********99999986533321456777799999999999776 PP

Organism

Chlorocebus sabaeus

Protein Sequence
(Fasta)

MHNFEEELTC PICYSIFEDP RVLPCSHTFC RNCLENILQA SGNFYIWRPL RIPLKCPNCR 60
SIIEIAPTGI ESLPVNFALR AIIEKYQQED HPDIVTCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCACAATT TTGAGGAAGA GTTAACTTGT CCCATATGTT ACAGTATTTT TGAAGATCCT 60
CGTGTACTGC CATGCTCTCA TACATTTTGT AGAAATTGTT TGGAAAACAT TCTTCAGGCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING

Gene Ontology

GO:0005783--C:endoplasmic reticulum
GO:0016021--C:integral component of membrane
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0043124--P:negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046597--P:negative regulation of viral entry into host cell

KEGG

csab:103241395

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002249	Ailuropoda melanoleuca	89.05	0.00e+00	745.00
IUUC-Apl-003996	Anas platyrhynchos	58.77	2.00e-125	442.00
IUUC-Aca-005141	Anolis carolinensis	57.28	2.00e-133	468.00
IUUC-Ame-011353	Astyanax mexicanus	53.59	1.00e-101	362.00
IUUC-Bta-013440	Bos taurus	91.16	0.00e+00	680.00
IUUC-Cfa-021168	Canis familiaris	89.53	0.00e+00	744.00
IUUC-Cpo-021702	Cavia porcellus	75.87	4.00e-178	617.00
IUUC-Dre-028408	Danio rerio	47.88	2.00e-89	322.00
IUUC-Dno-029180	Dasypus novemcinctus	88.34	0.00e+00	729.00
IUUC-Ete-033028	Echinops telfairi	87.62	1.00e-167	583.00
IUUC-Eca-034357	Equus caballus	89.33	0.00e+00	716.00
IUUC-Fca-036287	Felis catus	90.07	0.00e+00	748.00
IUUC-Gga-040739	Gallus gallus	57.64	3.00e-136	478.00
IUUC-Ggo-045307	Gorilla gorilla	94.29	0.00e+00	754.00
IUUC-Hsa-045690	Homo sapiens	94.54	0.00e+00	754.00
IUUC-Itr-048230	Ictidomys tridecemlineatus	91.07	0.00e+00	760.00
IUUC-Laf-054522	Loxodonta africana	86.07	0.00e+00	716.00
IUUC-Mcc-055145	Macaca mulatta	98.51	0.00e+00	784.00
IUUC-Mmr-061197	Microcebus murinus	92.80	0.00e+00	771.00
IUUC-Mdo-062631	Monodelphis domestica	60.74	4.00e-137	481.00
IUUC-Mmu-064217	Mus musculus	84.58	0.00e+00	681.00
IUUC-Mpu-065691	Mustela putorius furo	90.82	0.00e+00	758.00
IUUC-Mlu-067742	Myotis lucifugus	86.78	0.00e+00	691.00
IUUC-Nle-069722	Nomascus leucogenys	95.04	0.00e+00	787.00
IUUC-Oan-073382	Ornithorhynchus anatinus	61.19	2.00e-137	481.00
IUUC-Oar-089206	Ovis aries	88.83	0.00e+00	741.00
IUUC-Pan-092189	Papio anubis	98.76	0.00e+00	786.00
IUUC-Psi-093523	Pelodiscus sinensis	63.55	4.00e-146	510.00
IUUC-Pma-094162	Petromyzon marinus	33.64	3.00e-47	181.00
IUUC-Pfo-096032	Poecilia formosa	47.88	4.00e-89	321.00
IUUC-Pva-103089	Pteropus vampyrus	88.78	0.00e+00	710.00
IUUC-Pgr-103338	Puccinia graminis	36.23	9.00e-07	47.00
IUUC-Rno-105440	Rattus norvegicus	85.32	0.00e+00	687.00
IUUC-Ssc-115809	Sus scrofa	88.83	0.00e+00	708.00
IUUC-Tru-118402	Takifugu rubripes	44.63	3.00e-95	341.00
IUUC-Tni-119737	Tetraodon nigroviridis	45.13	4.00e-85	308.00
IUUC-Ttr-128921	Tursiops truncatus	89.53	0.00e+00	718.00
IUUC-Vpa-130397	Vicugna pacos	90.55	0.00e+00	752.00
IUUC-Xtr-132752	Xenopus tropicalis	42.55	2.00e-85	308.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence