iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-089600

Ensembl Protein ID

ENSOARP00000020518.1

UniProt Accession

W5QCS0; W5QCS0_SHEEP

Genbank Protein ID

ENSOARP00000020518

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01025789

Gene Name

RBCK1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000019106.1	ENSOART00000020801.1	ENSOARP00000020518.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
ULD/UDP/UBQ/UBQ_Other	5.40e-07	29.6	60	120

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

ULD/UDP/UBQ/UBQ_Other

   S: 4    tvksldgseltlk..vnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadyglk 62
            v++++  + t++  v p++tVa LK++++   g+pp  q++++ G+ L +d  tL ++g++
   Q: 60   SVEDAQMHTVTIWltVRPDMTVASLKDMVFLDYGFPPTLQQWVI-GQRLaRDQETLHSHGVR 120
           5666665577777889****************************.55555*********996 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MDEKIKKAEE VAQRLSRAVA GGDEQVAMQC AIWLAEQRVP LNVQLKPEVS PTQDIRLWVS 60
VEDAQMHTVT IWLTVRPDMT VASLKDMVFL DYGFPPTLQQ WVIGQRLARD QETLHSHGVR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCGCACCCC GGAGGGCGCT CCCGCTCCCA GCAGGGAGAA GGGCTCCGGC CTAGCGCCCT 60
GGCTGTGCGG CGCCCCTCCT CCCCTTCCCC GCAGCCAGGC CTGTCCAGTT TCCTCTGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR002867--IBR_dom
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50053--UBIQUITIN_2
PS01358--ZF_RANBP2_1
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF01485--IBR
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0060546--P:negative regulation of necroptotic process
GO:0032088--P:negative regulation of NF-kappaB transcription factor activity
GO:2001238--P:positive regulation of extrinsic apoptotic signaling pathway
GO:0042346--P:positive regulation of NF-kappaB import into nucleus
GO:0051092--P:positive regulation of NF-kappaB transcription factor activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination
GO:0050852--P:T cell receptor signaling pathway

KEGG

oas:101122207

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	89.61	0.00e+00	846.00
IUUC-Apl-003627	Anas platyrhynchos	58.11	2.00e-18	83.20
IUUC-Aca-004507	Anolis carolinensis	64.10	7.00e-151	526.00
IUUC-Ame-011008	Astyanax mexicanus	52.16	2.00e-141	495.00
IUUC-Bta-013247	Bos taurus	96.08	0.00e+00	912.00
IUUC-Cja-018880	Callithrix jacchus	90.98	0.00e+00	867.00
IUUC-Cfa-020477	Canis familiaris	91.37	0.00e+00	872.00
IUUC-Cpo-021558	Cavia porcellus	86.67	0.00e+00	822.00
IUUC-Csa-024129	Chlorocebus sabaeus	91.76	0.00e+00	829.00
IUUC-Cin-025630	Ciona intestinalis	37.93	2.00e-82	300.00
IUUC-Csv-026069	Ciona savignyi	50.80	5.00e-73	267.00
IUUC-Dre-027591	Danio rerio	50.48	7.00e-141	493.00
IUUC-Dno-029015	Dasypus novemcinctus	87.84	0.00e+00	828.00
IUUC-Dor-030313	Dipodomys ordii	81.67	0.00e+00	733.00
IUUC-Ete-032908	Echinops telfairi	78.00	0.00e+00	724.00
IUUC-Eca-034295	Equus caballus	76.94	0.00e+00	712.00
IUUC-Eeu-034454	Erinaceus europaeus	81.69	1.00e-113	403.00
IUUC-Fca-036380	Felis catus	91.76	0.00e+00	877.00
IUUC-Fal-037440	Ficedula albicollis	58.82	1.00e-14	70.50
IUUC-Gmo-038561	Gadus morhua	53.86	2.00e-121	429.00
IUUC-Gac-041319	Gasterosteus aculeatus	51.36	3.00e-137	481.00
IUUC-Ggo-044456	Gorilla gorilla	62.12	5.00e-141	494.00
IUUC-Hsa-045738	Homo sapiens	92.35	0.00e+00	830.00
IUUC-Itr-049042	Ictidomys tridecemlineatus	90.00	0.00e+00	829.00
IUUC-Lch-050269	Latimeria chalumnae	43.76	3.00e-113	402.00
IUUC-Loc-052776	Lepisosteus oculatus	62.86	1.00e-109	390.00
IUUC-Laf-054269	Loxodonta africana	88.04	0.00e+00	846.00
IUUC-Mcc-055669	Macaca mulatta	92.16	0.00e+00	844.00
IUUC-Mga-059615	Meleagris gallopavo	56.25	8.00e-18	81.30
IUUC-Mmr-061562	Microcebus murinus	89.85	0.00e+00	759.00
IUUC-Mdo-062263	Monodelphis domestica	75.58	0.00e+00	724.00
IUUC-Mmu-064325	Mus musculus	86.86	0.00e+00	803.00
IUUC-Mpu-066385	Mustela putorius furo	91.18	0.00e+00	874.00
IUUC-Mlu-067000	Myotis lucifugus	88.63	0.00e+00	831.00
IUUC-Nle-069812	Nomascus leucogenys	91.76	0.00e+00	838.00
IUUC-Opr-070575	Ochotona princeps	94.61	3.00e-106	379.00
IUUC-Ont-072405	Oreochromis niloticus	50.10	2.00e-134	472.00
IUUC-Ocu-074358	Oryctolagus cuniculus	78.12	0.00e+00	742.00
IUUC-Ola-086403	Oryzias latipes	52.60	4.00e-138	484.00
IUUC-Oga-087986	Otolemur garnettii	89.80	0.00e+00	811.00
IUUC-Ptr-091224	Pan troglodytes	92.16	0.00e+00	828.00
IUUC-Pan-092739	Papio anubis	92.35	0.00e+00	847.00
IUUC-Pma-094407	Petromyzon marinus	58.41	3.00e-104	372.00
IUUC-Pfo-097161	Poecilia formosa	52.30	6.00e-134	470.00
IUUC-Pab-098627	Pongo abelii	92.16	0.00e+00	823.00
IUUC-Pca-100641	Procavia capensis	88.68	0.00e+00	793.00
IUUC-Pva-102670	Pteropus vampyrus	89.41	0.00e+00	858.00
IUUC-Rno-105504	Rattus norvegicus	87.25	0.00e+00	800.00
IUUC-Sha-107342	Sarcophilus harrisii	74.42	0.00e+00	739.00
IUUC-Sar-113425	Sorex araneus	85.84	8.00e-110	390.00
IUUC-Ssc-115904	Sus scrofa	93.64	4.00e-89	320.00
IUUC-Tru-118096	Takifugu rubripes	51.35	8.00e-140	490.00
IUUC-Tni-119873	Tetraodon nigroviridis	50.49	2.00e-138	485.00
IUUC-Tbe-127578	Tupaia belangeri	88.42	0.00e+00	679.00
IUUC-Ttr-129107	Tursiops truncatus	93.33	0.00e+00	843.00
IUUC-Vpa-130353	Vicugna pacos	89.47	6.00e-114	404.00
IUUC-Xtr-132168	Xenopus tropicalis	42.80	2.00e-94	339.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence