iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000009559.5	ENSGALT00000046521.1	ENSGALP00000045900.1
ENSGALG00000009559.5	ENSGALT00000080084.1	ENSGALP00000052147.1
ENSGALG00000009559.5	ENSGALT00000015564.5	ENSGALP00000015548.5

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.90e-12	47.2	105	134

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H++ v + ++ s+ t l++ + Dg++k+W+
   Q: 105  HSGAVLAGRWnSEgTALATVGEDGQVKIWS 134
           7777777789888899*************8 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

MRLKTSLLKE PKHKELVSCV GWTTADELYS CSDDHQILKW NLLTSETSRV VKLPDDTYPI 60
DLHWLPRSVG GKKQSQAESF VLTSSDGKFH LISKVGRVEK SVEAHSGAVL AGRWNSEGTA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGTGCGGG CGGATGCCGA GGGCGGCGGG CACGGCCGGA GGGAGCGCGG CGGGGGACTG 60
GTCCTGAAGC AGAGATCCCG AGCGGTGCCG GTGGGGAAGC GGGGAGGCGG CCCGCCGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0060349--P:bone morphogenesis
GO:0002062--P:chondrocyte differentiation
GO:0060271--P:cilium assembly
GO:0050680--P:negative regulation of epithelial cell proliferation
GO:2000051--P:negative regulation of non-canonical Wnt signaling pathway
GO:1905515--P:non-motile cilium assembly
GO:0001649--P:osteoblast differentiation
GO:0045880--P:positive regulation of smoothened signaling pathway
GO:0007224--P:smoothened signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001564	Ailuropoda melanoleuca	88.71	0.00e+00	838.00
IUUC-Apl-003721	Anas platyrhynchos	96.80	0.00e+00	1504.00
IUUC-Aca-004488	Anolis carolinensis	88.09	0.00e+00	1399.00
IUUC-Ame-011402	Astyanax mexicanus	81.03	0.00e+00	814.00
IUUC-Bta-013037	Bos taurus	78.01	0.00e+00	1221.00
IUUC-Cel-018360	Caenorhabditis elegans	43.16	0.00e+00	684.00
IUUC-Cja-019076	Callithrix jacchus	75.89	0.00e+00	1123.00
IUUC-Cfa-020999	Canis familiaris	85.71	0.00e+00	1387.00
IUUC-Cpo-021333	Cavia porcellus	77.82	0.00e+00	1199.00
IUUC-Cre-022899	Chlamydomonas reinhardtii	46.66	0.00e+00	691.00
IUUC-Csa-023699	Chlorocebus sabaeus	85.47	0.00e+00	1382.00
IUUC-Cho-024904	Choloepus hoffmanni	78.70	0.00e+00	764.00
IUUC-Cin-025399	Ciona intestinalis	57.61	0.00e+00	956.00
IUUC-Csv-026186	Ciona savignyi	54.93	0.00e+00	919.00
IUUC-Dre-028276	Danio rerio	75.69	0.00e+00	1276.00
IUUC-Dno-029824	Dasypus novemcinctus	86.00	0.00e+00	1400.00
IUUC-Dor-031141	Dipodomys ordii	82.03	0.00e+00	1316.00
IUUC-Dme-031620	Drosophila melanogaster	36.34	8.00e-146	510.00
IUUC-Ete-033028	Echinops telfairi	62.34	4.00e-138	485.00
IUUC-Eca-033339	Equus caballus	85.77	0.00e+00	1380.00
IUUC-Eeu-034909	Erinaceus europaeus	84.84	0.00e+00	920.00
IUUC-Fca-035780	Felis catus	86.53	0.00e+00	1364.00
IUUC-Fal-037447	Ficedula albicollis	84.70	0.00e+00	1325.00
IUUC-Gmo-038657	Gadus morhua	61.79	0.00e+00	839.00
IUUC-Gac-041586	Gasterosteus aculeatus	71.82	0.00e+00	1014.00
IUUC-Hsa-047005	Homo sapiens	85.56	0.00e+00	1403.00
IUUC-Itr-048757	Ictidomys tridecemlineatus	87.37	0.00e+00	1035.00
IUUC-Lch-050459	Latimeria chalumnae	81.82	0.00e+00	1339.00
IUUC-Loc-052774	Lepisosteus oculatus	79.97	0.00e+00	1074.00
IUUC-Laf-053765	Loxodonta africana	85.37	0.00e+00	1345.00
IUUC-Mcc-055052	Macaca mulatta	85.47	0.00e+00	1382.00
IUUC-Meu-056368	Macropus eugenii	75.69	0.00e+00	1192.00
IUUC-Mga-059488	Meleagris gallopavo	98.71	0.00e+00	1529.00
IUUC-Mmr-061527	Microcebus murinus	86.27	0.00e+00	1381.00
IUUC-Mdo-062850	Monodelphis domestica	86.37	0.00e+00	1148.00
IUUC-Mmu-063117	Mus musculus	85.85	0.00e+00	1384.00
IUUC-Mpu-066550	Mustela putorius furo	85.94	0.00e+00	1265.00
IUUC-Mlu-067772	Myotis lucifugus	82.80	0.00e+00	1297.00
IUUC-Nle-069215	Nomascus leucogenys	84.78	0.00e+00	1390.00
IUUC-Opr-070725	Ochotona princeps	65.96	0.00e+00	1014.00
IUUC-Ont-072147	Oreochromis niloticus	74.07	0.00e+00	1263.00
IUUC-Oan-073176	Ornithorhynchus anatinus	89.38	1.00e-59	220.00
IUUC-Ocu-073896	Oryctolagus cuniculus	85.81	0.00e+00	1130.00
IUUC-Ola-086767	Oryzias latipes	68.24	0.00e+00	965.00
IUUC-Oga-088113	Otolemur garnettii	85.19	0.00e+00	1400.00
IUUC-Oar-089683	Ovis aries	82.34	0.00e+00	1326.00
IUUC-Ptr-091563	Pan troglodytes	85.70	0.00e+00	1404.00
IUUC-Pan-092042	Papio anubis	85.33	0.00e+00	1380.00
IUUC-Psi-093306	Pelodiscus sinensis	90.22	0.00e+00	1469.00
IUUC-Ppa-095694	Physcomitrella patens	46.33	0.00e+00	730.00
IUUC-Pfo-096800	Poecilia formosa	73.49	0.00e+00	1240.00
IUUC-Pab-098356	Pongo abelii	85.43	0.00e+00	1399.00
IUUC-Pva-102246	Pteropus vampyrus	80.97	0.00e+00	1290.00
IUUC-Rno-105195	Rattus norvegicus	84.79	0.00e+00	1386.00
IUUC-Sha-107056	Sarcophilus harrisii	87.22	0.00e+00	1406.00
IUUC-Smo-109240	Selaginella moellendorffii	43.95	1.00e-178	619.00
IUUC-Sar-113301	Sorex araneus	77.55	9.00e-138	484.00
IUUC-Ssc-116040	Sus scrofa	87.40	2.00e-134	471.00
IUUC-Tgu-117127	Taeniopygia guttata	86.11	0.00e+00	1368.00
IUUC-Tru-118663	Takifugu rubripes	72.02	0.00e+00	1216.00
IUUC-Tsy-119207	Tarsius syrichta	84.25	0.00e+00	792.00
IUUC-Tni-120705	Tetraodon nigroviridis	71.71	0.00e+00	1211.00
IUUC-Tbe-127434	Tupaia belangeri	72.40	0.00e+00	881.00
IUUC-Ttr-128937	Tursiops truncatus	86.18	0.00e+00	1395.00
IUUC-Vpa-130518	Vicugna pacos	82.01	0.00e+00	1288.00
IUUC-Xtr-131879	Xenopus tropicalis	78.08	0.00e+00	1279.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence