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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063091
Ensembl Protein ID ENSMUSP00000129589.1
UniProt Accession Q9CXX9; Q99LC1; CUED2_MOUSE
Genbank Protein ID BAE19943.1; BAB29035.1; AAH03442.1
Protein Name CUE domain-containing protein 2
Genbank Nucleotide ID AB232359; AK013884; BC003442
Gene Name Cuedc2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000036748.15 ENSMUST00000167861.7 ENSMUSP00000129589.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
UBD/Alpha-Helix/CUE 87.11 1.00e-141 499.00 IUUC-Hsa-046256
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     Controls PGR and ESR1 protein levels through their targeting for ubiquitination and subsequent proteasomal degradation.
 Controls PGR and ESR1 protein levels through their targeting for ubiquitination and subsequent proteasomal degradation.
Protein Sequence
(Fasta)
MELERIVGSA LLTFVQAHLP EADLSGLDEV IFSYVLGVLE DLGPSGPSEE NFDMEAFTEM 60
MEAYVPGFAH IPRGIIGDMM QKLSVQLSDA RNKENLHPQS SCVQGQVPIF PETPRQAEKL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063091|UBD,CUE|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGGCCCCGCC TTTGATCTCG TTGGTGGGGC TAGGGGGGGT GATAAGAACT GCACCGCGCG 60
GGACAAGTTG CTGGCGGCGC CTGACGGAGC AGGTGATTTC CCCTCCGGCC TTAGGAGAGT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063091|UBD,CUE|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0833--Ubl conjugation pathway
Interpro

IPR003892--CUE
PROSITE

PS51140--CUE
Gene Ontology

GO:0005829--C:cytosol
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:1900016--P:negative regulation of cytokine production involved in inflammatory response
GO:0010936--P:negative regulation of macrophage cytokine production
KEGG mmu:67116
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001790 Ailuropoda melanoleuca 88.11 2.00e-141 494.00
IUUC-Apl-003944 Anas platyrhynchos 53.79 2.00e-72 265.00
IUUC-Ago-007785 Ashbya gossypii 35.85 6.30e-01 28.90
IUUC-Acl-008346 Aspergillus clavatus 36.11 7.10e+00 26.60
IUUC-Afl-008434 Aspergillus flavus 36.36 2.50e+00 26.60
IUUC-Ang-009821 Aspergillus niger 40.74 2.00e-02 33.90
IUUC-Ame-011202 Astyanax mexicanus 45.64 9.00e-67 246.00
IUUC-Bta-012549 Bos taurus 73.17 3.00e-112 397.00
IUUC-Cja-019719 Callithrix jacchus 81.25 3.00e-128 451.00
IUUC-Cfa-021223 Canis familiaris 87.41 4.00e-144 503.00
IUUC-Cpo-021485 Cavia porcellus 85.21 3.00e-138 484.00
IUUC-Cre-022630 Chlamydomonas reinhardtii 63.64 2.20e-01 30.80
IUUC-Csa-023808 Chlorocebus sabaeus 84.67 6.00e-134 469.00
IUUC-Cne-026987 Cryptococcus neoformans 32.43 3.60e+00 27.70
IUUC-Dre-027377 Danio rerio 42.36 2.00e-53 202.00
IUUC-Dno-029148 Dasypus novemcinctus 83.97 3.00e-137 481.00
IUUC-Dor-030884 Dipodomys ordii 86.59 6.00e-122 429.00
IUUC-Dme-031833 Drosophila melanogaster 27.84 1.00e-29 123.00
IUUC-Eca-033224 Equus caballus 87.11 2.00e-142 498.00
IUUC-Fca-036557 Felis catus 87.11 1.00e-139 489.00
IUUC-Fal-036631 Ficedula albicollis 54.42 1.00e-77 283.00
IUUC-Fso-038371 Fusarium solani 35.14 4.80e+00 26.90
IUUC-Gmo-038930 Gadus morhua 44.67 1.00e-63 236.00
IUUC-Gga-041066 Gallus gallus 55.10 2.00e-75 275.00
IUUC-Gac-041736 Gasterosteus aculeatus 44.22 1.00e-65 243.00
IUUC-Ggo-045551 Gorilla gorilla 85.07 2.00e-133 468.00
IUUC-Hsa-046256 Homo sapiens 85.37 4.00e-135 473.00
IUUC-Itr-047925 Ictidomys tridecemlineatus 87.06 6.00e-145 506.00
IUUC-Lch-049728 Latimeria chalumnae 57.45 6.00e-43 166.00
IUUC-Loc-052375 Lepisosteus oculatus 46.53 3.00e-60 224.00
IUUC-Laf-054367 Loxodonta africana 83.92 3.00e-135 474.00
IUUC-Mcc-055535 Macaca mulatta 85.12 1.00e-134 472.00
IUUC-Meu-056716 Macropus eugenii 56.99 7.00e-84 303.00
IUUC-Mla-059087 Melampsora laricipopulina 31.19 2.70e-01 28.10
IUUC-Mga-059259 Meleagris gallopavo 55.07 8.00e-76 276.00
IUUC-Mdo-062874 Monodelphis domestica 55.56 5.00e-58 217.00
IUUC-Mpu-066538 Mustela putorius furo 87.11 2.00e-140 491.00
IUUC-Mlu-068118 Myotis lucifugus 84.97 6.00e-136 476.00
IUUC-Nle-069262 Nomascus leucogenys 85.37 4.00e-135 473.00
IUUC-Opr-070887 Ochotona princeps 83.22 1.00e-131 462.00
IUUC-Ont-072566 Oreochromis niloticus 44.59 6.00e-65 240.00
IUUC-Oan-073555 Ornithorhynchus anatinus 54.64 1.00e-82 299.00
IUUC-Ocu-073954 Oryctolagus cuniculus 85.71 4.00e-140 490.00
IUUC-Ola-087131 Oryzias latipes 41.72 2.00e-56 212.00
IUUC-Oga-088232 Otolemur garnettii 81.18 6.00e-118 416.00
IUUC-Oar-090288 Ovis aries 80.42 8.00e-126 442.00
IUUC-Ptr-091641 Pan troglodytes 85.37 4.00e-135 473.00
IUUC-Pan-092307 Papio anubis 85.03 2.00e-140 491.00
IUUC-Psi-093174 Pelodiscus sinensis 49.82 6.00e-58 217.00
IUUC-Pfo-096255 Poecilia formosa 46.13 4.00e-65 241.00
IUUC-Pab-098066 Pongo abelii 85.52 8.00e-140 489.00
IUUC-Pca-101113 Procavia capensis 81.12 2.00e-126 444.00
IUUC-Pva-102662 Pteropus vampyrus 83.57 2.00e-127 448.00
IUUC-Rno-105183 Rattus norvegicus 84.21 2.00e-122 431.00
IUUC-Sha-107507 Sarcophilus harrisii 59.04 1.00e-93 335.00
IUUC-Spo-108252 Schizosaccharomyces pombe 24.67 3.40e-01 30.00
IUUC-Sre-115033 Sporisorium reilianum 37.84 1.70e+00 28.50
IUUC-Ssc-115243 Sus scrofa 63.64 8.00e-55 209.00
IUUC-Tgu-117106 Taeniopygia guttata 54.17 2.00e-73 268.00
IUUC-Tru-117992 Takifugu rubripes 45.15 2.00e-64 238.00
IUUC-Tni-120145 Tetraodon nigroviridis 44.95 3.00e-66 244.00
IUUC-Tbe-127268 Tupaia belangeri 87.39 2.00e-108 384.00
IUUC-Uma-129410 Ustilago maydis 37.84 2.50e+00 28.10
IUUC-Xtr-132299 Xenopus tropicalis 50.35 1.00e-73 269.00
IUUC-Xma-133702 Xiphophorus maculatus 46.48 4.00e-66 244.00
Created Date 25-Jun-2017

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