iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000001706.1	ENSLOCT00000001989.1	ENSLOCP00000001984.1
ENSLOCG00000001706.1	ENSLOCT00000002006.1	ENSLOCP00000002001.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.30e-87	294.3	276	609

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsn..ipelrelllekkkeklneenpkepkgellkslqklfeelw.kskkkavsprellkalkkeaeefsg 86
           +Gl+NlgNt  m  +L  L+   ++ + ++l  +++++ + +n++ ++++l+++++kl++ lw +++++avsp+e++++++k+a++f g
   Q: 276  VGLRNLGNTVSMRVILLGLYTmaTTCFSKQLCFHNSHRRDLNNNSRTNTALMEEFAKLIQTLWtSTSSEAVSPSEFKTQIQKYAPRFVG 364
           6******************973345566665555555555566689*****************99999********************* PP
   S: 87   yeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde...aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           y+qqDaqEfl+flld+l++e+++ +  p+ ++e+ d+   +++    ++k  ++++s i+dlF gqlks+++c +c+  s+ ++pf+dl
   Q: 365  YNQQDAQEFLRFLLDGLHNEVNRVTVRPRATMEDLDHLPDDEKgkrMWNKYLEREDSRIVDLFVGQLKSSLTCSDCGYCSTVFDPFWDL 453
           **********************9888888888888855444447779****************************************** PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefple.Ld 260
           slp+ +k    + sl dc++ ftke+ l+g++k  c +ck++++++kk++++k+P++L+lhLkRf  se++ + +k+++ v+fpl+ Ld
   Q: 454  SLPIAKKGYG-EVSLMDCMRLFTKEDVLDGDEKPTCYRCKARRKCTKKFTIQKFPKILVLHLKRF--SEARVRTSKLSTFVSFPLKdLD 539
           *****99976.779***************************************************..9999****************** PP
   S: 261  lspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           l++f ++++     +  Y+L+av +HsG++ +GHY+ay++n + + W +f+Ds+Vt+++  +v +   s+aYvlfY+
   Q: 540  LREFASENSI----HAVYNLYAVSNHSGTTMGGHYTAYCRNPSTGeWHTFNDSRVTPMSSGQVRT---SDAYVLFYE 609
           ******9443....78*************************65555*******************...********8 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

MSRASSTAKR YTSTYTSHYG SYSSSLASGL GSYGERDKLS YKSPSSSYTP SSYLSMGASR 60
ARNHSTSSEP DRGRPVPRAD ILGSRRSESL SRTPGKGYSS GLSGGGGYAG YSYSPTQPSY 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTCGTG CTTCCTCCAC GGCCAAGCGC TACACCTCCA CCTACACCAG CCACTATGGC 60
TCCTACAGTT CCTCCTTGGC GTCGGGCCTG GGCTCCTATG GAGAGCGGGA CAAGCTTTCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001988	Ailuropoda melanoleuca	55.01	1.00e-162	566.00
IUUC-Aca-005132	Anolis carolinensis	75.57	2.00e-160	559.00
IUUC-Ame-011102	Astyanax mexicanus	80.00	1.00e-156	545.00
IUUC-Bta-012529	Bos taurus	59.85	2.00e-153	536.00
IUUC-Cja-019016	Callithrix jacchus	53.85	1.00e-146	513.00
IUUC-Cfa-020714	Canis familiaris	56.30	3.00e-165	575.00
IUUC-Cpo-021727	Cavia porcellus	56.49	9.00e-162	563.00
IUUC-Csa-023071	Chlorocebus sabaeus	78.63	5.00e-158	550.00
IUUC-Cin-025797	Ciona intestinalis	49.71	2.00e-95	342.00
IUUC-Csv-026132	Ciona savignyi	48.53	8.00e-92	330.00
IUUC-Dre-027872	Danio rerio	81.77	1.00e-172	598.00
IUUC-Dno-029329	Dasypus novemcinctus	55.59	7.00e-171	593.00
IUUC-Dor-030574	Dipodomys ordii	56.32	4.00e-158	551.00
IUUC-Dme-032208	Drosophila melanogaster	46.49	3.00e-74	273.00
IUUC-Eca-033361	Equus caballus	54.65	9.00e-162	563.00
IUUC-Eeu-035272	Erinaceus europaeus	84.15	1.00e-87	317.00
IUUC-Fca-036497	Felis catus	56.13	1.00e-164	572.00
IUUC-Fal-036766	Ficedula albicollis	77.56	7.00e-157	547.00
IUUC-Gmo-039129	Gadus morhua	63.08	1.00e-125	442.00
IUUC-Gga-040889	Gallus gallus	72.81	5.00e-134	471.00
IUUC-Gac-042475	Gasterosteus aculeatus	68.64	8.00e-140	489.00
IUUC-Ggo-044814	Gorilla gorilla	71.70	5.00e-140	490.00
IUUC-Hsa-045937	Homo sapiens	78.57	3.00e-157	548.00
IUUC-Itr-048171	Ictidomys tridecemlineatus	57.10	6.00e-163	567.00
IUUC-Lch-050527	Latimeria chalumnae	83.48	9.00e-175	606.00
IUUC-Laf-054167	Loxodonta africana	78.19	2.00e-163	568.00
IUUC-Mcc-055584	Macaca mulatta	54.69	1.00e-160	559.00
IUUC-Meu-056542	Macropus eugenii	77.62	5.00e-157	547.00
IUUC-Mga-060020	Meleagris gallopavo	77.87	3.00e-155	541.00
IUUC-Mmr-060989	Microcebus murinus	55.87	5.00e-163	567.00
IUUC-Mdo-062761	Monodelphis domestica	77.62	5.00e-157	547.00
IUUC-Mmu-063710	Mus musculus	55.78	9.00e-161	560.00
IUUC-Mpu-066573	Mustela putorius furo	55.62	9.00e-163	566.00
IUUC-Nle-070013	Nomascus leucogenys	54.25	2.00e-150	525.00
IUUC-Opr-070907	Ochotona princeps	78.29	1.00e-156	546.00
IUUC-Ont-071944	Oreochromis niloticus	87.75	0.00e+00	625.00
IUUC-Oan-073105	Ornithorhynchus anatinus	73.29	4.00e-134	470.00
IUUC-Ocu-073941	Oryctolagus cuniculus	78.57	2.00e-157	548.00
IUUC-Ola-087412	Oryzias latipes	82.00	6.00e-159	554.00
IUUC-Oga-088973	Otolemur garnettii	55.35	6.00e-161	560.00
IUUC-Oar-089916	Ovis aries	55.73	4.00e-165	574.00
IUUC-Ptr-090998	Pan troglodytes	78.57	2.00e-157	549.00
IUUC-Pan-092686	Papio anubis	54.84	5.00e-161	561.00
IUUC-Psi-093284	Pelodiscus sinensis	64.94	2.00e-109	388.00
IUUC-Pma-094462	Petromyzon marinus	63.59	5.00e-70	256.00
IUUC-Pno-094986	Phaeosphaeria nodorum	33.53	7.00e-45	176.00
IUUC-Pfo-097352	Poecilia formosa	86.65	0.00e+00	638.00
IUUC-Pab-098688	Pongo abelii	49.53	1.00e-129	456.00
IUUC-Pca-100205	Procavia capensis	76.29	1.00e-153	536.00
IUUC-Pva-103188	Pteropus vampyrus	78.57	5.00e-156	544.00
IUUC-Pte-104348	Pyrenophora teres	32.33	4.00e-43	170.00
IUUC-Rno-105853	Rattus norvegicus	55.85	7.00e-161	560.00
IUUC-Sha-107237	Sarcophilus harrisii	77.34	6.00e-157	547.00
IUUC-Sar-113103	Sorex araneus	75.14	3.00e-147	514.00
IUUC-Ssc-115955	Sus scrofa	56.67	2.00e-156	545.00
IUUC-Tgu-116894	Taeniopygia guttata	77.90	5.00e-156	543.00
IUUC-Tru-117703	Takifugu rubripes	65.34	7.00e-130	456.00
IUUC-Tsy-118879	Tarsius syrichta	78.86	3.00e-157	548.00
IUUC-Tni-119866	Tetraodon nigroviridis	80.99	4.00e-167	580.00
IUUC-Ttr-128773	Tursiops truncatus	55.40	5.00e-159	554.00
IUUC-Vpa-130402	Vicugna pacos	84.68	1.00e-108	386.00
IUUC-Xtr-132658	Xenopus tropicalis	77.90	9.00e-155	540.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence