iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Gac-041867

UUCD1 version

UUC-GaA-01261

Ensembl Protein ID

ENSGACP00000027459.1

UniProt Accession

G3QC43; G3QC43_GASAC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGACG00000020768.1	ENSGACT00000027511.1	ENSGACP00000027459.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.10e-57	196.2	163	648

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.....kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeef 84
           +G++N+gNtC++ +v+Q+L+++p +r+l+l+     +  ek++  + ++++ +++++l+ lf+ ++ s+++ v+p++ ++ l+++ +  
   Q: 163  VGIRNVGNTCWFSAVIQSLFHLPVFRRLVLSyhlseRILEKCKSHS-DKRNIAFMQELRCLFALMVGSTRRFVDPSAAVELLRDAFRT- 249
           6******************************999887788887664.79999*******************************99986. PP
   S: 85   sgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldls 173
           ++ +q+D++Ef + lld le+++                 +l  +  +k + k+k+++++lF g++ ++ +  + +++    e+f +++
   Q: 250  NEAQQHDVSEFSHKLLDWLEDAF-----------------QLAANDFSKVEDKQKNPMVQLFYGTFVTERR--HEGKTLCNIEQFGQYP 319
           9**********************.................23333347889999************96655..567777889******* PP
   S: 174  lpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdls 262
           l+v+g +     +l++cLe  + e e+e+   +++   ++++++ ++ ++kklP+vL+++L+Rf+f+ + +++eki+kk+ef + + ++
   Q: 320  LQVNGFN-----NLDECLEGAMVEREIES---LHS---EHSVTSGRERWFKKLPPVLTFELSRFEFNTQLGRPEKIHKKLEFSQIIYMD 397
           *******.....9*********9999995...555...456778899****************************************** PP
   S: 263  pfcts..........................................................................peekqke... 274
           +++++                                                                                    
   Q: 398  RYLHKnigqtherrgevkklkeqlaalqqklecyknygsgptkypladmlqfvlefsttkptcvspaedlgpasptpasH-----Plsd 481
           *****777666666666666666666666666666666666666555555555555555555555555555555555550.....0555 PP
   S: 275  ......................................................................................... 274
                                                                                                    
   Q: 482  liskdnsepedsdasegavsgvsscqrtpiykpftqcrlpvdcpphpaphsvteeelhfvktclqrwrtevendinelkasidrltqvl 570
           55555555566666677777777777777788888888888888888888888888888888888888888889999999999999999 PP
   S: 275  ..........kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                     +  Y+L+av+vH+G++s GHY+ay++++ ++ W++++D ++te+++ee ++++      ++aY+l+Y 
   Q: 571  egmyadnclcQAPYRLHAVLVHEGQASAGHYWAYIYDHANQrWMKYNDISITESSWEELERDSFggmtnASAYCLMYI 648
           99999999999**************************88888*******************87799***********6 PP

Organism

Gasterosteus aculeatus

Protein Sequence
(Fasta)

LLVYLTPDCC FPLSDLFTRQ SKILIDQLRE ITGIQDPQVL NRALNASQGD IGNAVGLLTT 60
QPAEVQDPGE TQEPGPSAEA WDGQKGTLGL LSDFSGPPKD ELQTAIELSL QESHKAQEEE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGCTAGTAT ATCTCACGCC TGACTGTTGT TTCCCTTTGT CCGATCTTTT CACTCGCCAG 60
AGCAAGATCC TGATCGACCA GCTGAGGGAG ATCACTGGCA TCCAGGACCC CCAGGTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR009060--UBA-like
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001836	Ailuropoda melanoleuca	54.55	0.00e+00	1131.00
IUUC-Apl-004010	Anas platyrhynchos	52.49	0.00e+00	1091.00
IUUC-Aca-004741	Anolis carolinensis	53.03	0.00e+00	695.00
IUUC-Acl-008164	Aspergillus clavatus	36.19	5.00e-12	67.40
IUUC-Ang-009577	Aspergillus niger	33.59	5.00e-11	63.90
IUUC-Ate-010275	Aspergillus terreus	30.17	2.00e-10	61.60
IUUC-Bgr-011993	Blumeria graminis	37.84	6.00e-12	67.00
IUUC-Bta-013377	Bos taurus	54.37	0.00e+00	1105.00
IUUC-Cja-019977	Callithrix jacchus	53.89	0.00e+00	1123.00
IUUC-Cfa-020378	Canis familiaris	58.46	0.00e+00	761.00
IUUC-Cpo-021817	Cavia porcellus	53.88	0.00e+00	1112.00
IUUC-Csa-023446	Chlorocebus sabaeus	55.57	0.00e+00	745.00
IUUC-Cho-024717	Choloepus hoffmanni	46.36	0.00e+00	653.00
IUUC-Csv-025911	Ciona savignyi	36.22	1.00e-141	497.00
IUUC-Cme-027167	Cyanidioschyzon merolae	31.22	4.00e-16	80.90
IUUC-Dre-028105	Danio rerio	73.43	0.00e+00	991.00
IUUC-Dor-030955	Dipodomys ordii	53.13	0.00e+00	1077.00
IUUC-Ete-032828	Echinops telfairi	48.59	0.00e+00	676.00
IUUC-Eca-034300	Equus caballus	54.04	0.00e+00	1094.00
IUUC-Eeu-034458	Erinaceus europaeus	53.39	0.00e+00	976.00
IUUC-Fca-035753	Felis catus	55.43	0.00e+00	1146.00
IUUC-Gmo-039593	Gadus morhua	73.23	0.00e+00	1533.00
IUUC-Ggo-045384	Gorilla gorilla	53.80	0.00e+00	1121.00
IUUC-Hsa-046277	Homo sapiens	53.80	0.00e+00	1118.00
IUUC-Itr-048276	Ictidomys tridecemlineatus	48.55	0.00e+00	627.00
IUUC-Kpa-049349	Komagataella pastoris	34.78	8.00e-10	60.10
IUUC-Lch-049692	Latimeria chalumnae	58.10	0.00e+00	1201.00
IUUC-Laf-053808	Loxodonta africana	50.96	0.00e+00	1054.00
IUUC-Mcc-055473	Macaca mulatta	55.57	0.00e+00	745.00
IUUC-Meu-056416	Macropus eugenii	46.28	0.00e+00	869.00
IUUC-Mga-060011	Meleagris gallopavo	52.68	0.00e+00	1062.00
IUUC-Mvi-060527	Microbotryum violaceum	26.06	6.00e-09	57.00
IUUC-Mmr-060720	Microcebus murinus	54.00	0.00e+00	1082.00
IUUC-Mdo-061955	Monodelphis domestica	54.66	0.00e+00	1102.00
IUUC-Mmu-063870	Mus musculus	57.73	0.00e+00	766.00
IUUC-Mpu-066454	Mustela putorius furo	56.43	0.00e+00	756.00
IUUC-Mlu-067487	Myotis lucifugus	53.09	0.00e+00	1069.00
IUUC-Nle-070044	Nomascus leucogenys	53.39	0.00e+00	1113.00
IUUC-Opr-070888	Ochotona princeps	64.31	1.00e-96	348.00
IUUC-Ont-072386	Oreochromis niloticus	87.55	0.00e+00	1234.00
IUUC-Ocu-074523	Oryctolagus cuniculus	53.35	0.00e+00	1090.00
IUUC-Ola-086393	Oryzias latipes	77.16	0.00e+00	1658.00
IUUC-Oga-088618	Otolemur garnettii	53.69	0.00e+00	1114.00
IUUC-Oar-089848	Ovis aries	53.49	0.00e+00	1138.00
IUUC-Psi-093422	Pelodiscus sinensis	54.34	0.00e+00	732.00
IUUC-Pma-094250	Petromyzon marinus	46.37	9.00e-66	243.00
IUUC-Pno-095093	Phaeosphaeria nodorum	43.42	1.00e-12	68.90
IUUC-Pfo-096466	Poecilia formosa	85.04	0.00e+00	1234.00
IUUC-Pab-098337	Pongo abelii	53.39	0.00e+00	1112.00
IUUC-Pva-102226	Pteropus vampyrus	51.99	0.00e+00	998.00
IUUC-Pte-104300	Pyrenophora teres	21.78	6.00e-12	67.00
IUUC-Rno-105735	Rattus norvegicus	57.27	0.00e+00	759.00
IUUC-Sha-107489	Sarcophilus harrisii	55.29	0.00e+00	1149.00
IUUC-Spo-108381	Schizosaccharomyces pombe	37.86	3.00e-11	64.70
IUUC-Ssl-108532	Sclerotinia sclerotiorum	31.48	1.00e-09	59.70
IUUC-Tgu-116609	Taeniopygia guttata	53.04	0.00e+00	1048.00
IUUC-Tru-117807	Takifugu rubripes	76.14	0.00e+00	1605.00
IUUC-Tni-119983	Tetraodon nigroviridis	77.09	0.00e+00	1674.00
IUUC-Ttr-128887	Tursiops truncatus	51.02	0.00e+00	1007.00
IUUC-Vda-129742	Verticillium dahliae	25.94	2.00e-10	62.00
IUUC-Vpa-130614	Vicugna pacos	54.49	0.00e+00	861.00
IUUC-Xtr-132436	Xenopus tropicalis	51.35	0.00e+00	1026.00
IUUC-Xma-133995	Xiphophorus maculatus	85.30	0.00e+00	1193.00
IUUC-Yli-134560	Yarrowia lipolytica	31.85	4.00e-12	67.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence