iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062527

UUCD1 version

UUC-MoD-00525

Ensembl Protein ID

ENSMODP00000025940.3

UniProt Accession

F7A032; F7A032_MONDO

Protein Name

Uncharacterized protein

Gene Name

KLHL8

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000020741.3	ENSMODT00000026404.3	ENSMODP00000025940.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	1.90e-17	63.5	83	148
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	1.80e-09	36.7	182	212

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +Dv+l+vg + + +hk+vLa   ++F+a+fl+e+ es+ ++ +ei+d + ++ ++l+kF+Y+++l++
   Q: 83   CDVTLKVGSKLITCHKLVLACVIPYFRAMFLSEMAESN-QSLIEIRDFDGDAIEDLVKFVYSSRLTL 148
           9************************************9.*************************986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfilkhF 31
           ++Ncl++++fA+ ++  dL+d a+++++ hF
   Q: 182  PSNCLAVRAFAESHNRIDLMDMADRYACEHF 212
           89****************************9 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MCEQINVERE MLTMASESLC PEPPKTYLIK GKNQQQQPPH RQQEDISSNI DGNREESYTF 60
EANEAWKDFH SSLLRFYEDG ELCDVTLKVG SKLITCHKLV LACVIPYFRA MFLSEMAESN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATAGTCATGA CTCTGGGGTC TTTAAATAGC TAAATCCTTG ATGAATTTCA GTGAGAGAAA 60
CTGGGACTTT TTTTTCCTCC TTTCTACCTA CATTGACCTC ATAGCTTTGA ATGGAGAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR030605--KLHL8
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mdo:100017063

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001443	Ailuropoda melanoleuca	89.73	0.00e+00	1139.00
IUUC-Atr-002726	Amborella trichopoda	36.73	3.00e-42	167.00
IUUC-Apl-003978	Anas platyrhynchos	88.46	0.00e+00	1147.00
IUUC-Aca-004958	Anolis carolinensis	85.42	0.00e+00	1080.00
IUUC-Ame-011139	Astyanax mexicanus	84.58	0.00e+00	1064.00
IUUC-Bta-013142	Bos taurus	88.76	0.00e+00	1130.00
IUUC-Cel-018551	Caenorhabditis elegans	40.21	8.00e-129	454.00
IUUC-Cja-019650	Callithrix jacchus	89.41	0.00e+00	1162.00
IUUC-Cfa-021046	Canis familiaris	89.57	0.00e+00	1135.00
IUUC-Cpo-022445	Cavia porcellus	87.80	0.00e+00	1096.00
IUUC-Csa-023642	Chlorocebus sabaeus	89.25	0.00e+00	1161.00
IUUC-Cho-025012	Choloepus hoffmanni	75.04	0.00e+00	848.00
IUUC-Dre-027723	Danio rerio	82.34	0.00e+00	1048.00
IUUC-Dno-028964	Dasypus novemcinctus	88.18	0.00e+00	941.00
IUUC-Dor-030899	Dipodomys ordii	78.15	6.00e-128	451.00
IUUC-Ete-032815	Echinops telfairi	87.00	0.00e+00	1121.00
IUUC-Eca-034162	Equus caballus	92.54	0.00e+00	1128.00
IUUC-Eeu-034660	Erinaceus europaeus	88.28	0.00e+00	1115.00
IUUC-Fca-035659	Felis catus	89.41	0.00e+00	1135.00
IUUC-Fal-037619	Ficedula albicollis	89.41	0.00e+00	1152.00
IUUC-Gmo-038546	Gadus morhua	84.31	0.00e+00	1038.00
IUUC-Ggr-040041	Gaeumannomyces graminis	30.61	1.00e-06	47.40
IUUC-Gga-040770	Gallus gallus	88.76	0.00e+00	1125.00
IUUC-Gac-042557	Gasterosteus aculeatus	77.37	0.00e+00	1032.00
IUUC-Ggo-044741	Gorilla gorilla	89.09	0.00e+00	1160.00
IUUC-Hsa-046025	Homo sapiens	89.09	0.00e+00	1160.00
IUUC-Itr-048541	Ictidomys tridecemlineatus	93.62	0.00e+00	1061.00
IUUC-Loc-052834	Lepisosteus oculatus	87.04	0.00e+00	1008.00
IUUC-Laf-054513	Loxodonta africana	92.75	0.00e+00	1137.00
IUUC-Mcc-054707	Macaca mulatta	89.09	0.00e+00	1157.00
IUUC-Meu-056779	Macropus eugenii	93.74	0.00e+00	1191.00
IUUC-Mga-059676	Meleagris gallopavo	88.60	0.00e+00	1124.00
IUUC-Mmr-061359	Microcebus murinus	87.64	0.00e+00	1113.00
IUUC-Mmu-063112	Mus musculus	86.01	0.00e+00	1125.00
IUUC-Mpu-065800	Mustela putorius furo	89.14	0.00e+00	1136.00
IUUC-Mlu-067536	Myotis lucifugus	87.38	0.00e+00	1094.00
IUUC-Nle-069397	Nomascus leucogenys	89.09	0.00e+00	1159.00
IUUC-Opr-070599	Ochotona princeps	88.16	0.00e+00	939.00
IUUC-Ont-072580	Oreochromis niloticus	84.31	0.00e+00	1046.00
IUUC-Oan-073180	Ornithorhynchus anatinus	91.01	0.00e+00	1163.00
IUUC-Ocu-074026	Oryctolagus cuniculus	91.86	0.00e+00	1120.00
IUUC-Ola-086776	Oryzias latipes	83.79	0.00e+00	1001.00
IUUC-Oga-088651	Otolemur garnettii	88.92	0.00e+00	1132.00
IUUC-Oar-089567	Ovis aries	87.64	0.00e+00	1104.00
IUUC-Ptr-091564	Pan troglodytes	89.09	0.00e+00	1160.00
IUUC-Pan-092578	Papio anubis	89.25	0.00e+00	1161.00
IUUC-Psi-093635	Pelodiscus sinensis	88.61	0.00e+00	1097.00
IUUC-Pma-094660	Petromyzon marinus	61.51	0.00e+00	767.00
IUUC-Pfo-097507	Poecilia formosa	83.92	0.00e+00	971.00
IUUC-Pab-098025	Pongo abelii	89.09	0.00e+00	1160.00
IUUC-Pca-101046	Procavia capensis	83.56	5.00e-176	610.00
IUUC-Ppe-101154	Prunus persica	32.28	8.00e-38	152.00
IUUC-Pva-102359	Pteropus vampyrus	93.41	0.00e+00	868.00
IUUC-Rno-105750	Rattus norvegicus	86.52	0.00e+00	1121.00
IUUC-Sha-107513	Sarcophilus harrisii	93.91	0.00e+00	1206.00
IUUC-Sly-111482	Solanum lycopersicum	32.68	2.00e-41	164.00
IUUC-Stu-112032	Solanum tuberosum	33.07	3.00e-42	166.00
IUUC-Sar-113616	Sorex araneus	68.15	3.00e-113	402.00
IUUC-Ssc-116205	Sus scrofa	88.37	0.00e+00	946.00
IUUC-Tgu-117435	Taeniopygia guttata	89.57	0.00e+00	1154.00
IUUC-Tru-118709	Takifugu rubripes	83.45	0.00e+00	1041.00
IUUC-Tsy-119466	Tarsius syrichta	93.43	0.00e+00	1059.00
IUUC-Tni-119988	Tetraodon nigroviridis	82.74	0.00e+00	1043.00
IUUC-Tbe-127704	Tupaia belangeri	91.42	0.00e+00	1014.00
IUUC-Ttr-128892	Tursiops truncatus	92.87	0.00e+00	882.00
IUUC-Vpa-130545	Vicugna pacos	89.32	0.00e+00	951.00
IUUC-Xtr-132289	Xenopus tropicalis	81.88	0.00e+00	1012.00
IUUC-Xma-133419	Xiphophorus maculatus	84.03	0.00e+00	948.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence