iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ocu-074936

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAGW02011155

Gene Name

SH3RF1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000003098.3	ENSOCUT00000031902.2	ENSOCUP00000023060.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.80e-08	33.2	12	53
UBD/SH3	4.10e-48	161.2	457	512

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cle+++   +vlpC+H+f++ Cl  +      s++e rCP Cr
   Q: 12   CPVCLERLDASAKVLPCQHTFCKRCLLGI----VGSRNELRCPECR 53
           **********9**************9777....899*********8 PP

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
           +  ++y+y++ ++deL+l+kG++ lv  + +   gW kg++  + k G+fP n+v+ +
   Q: 457  VYVAIYPYTPRKEDELELRKGEMFLVF-ERC-QDGWFKGTSMHTSKIGVFPGNYVAPV 512
           5679**********************9.555.569********************988 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MDESALLDLL ECPVCLERLD ASAKVLPCQH TFCKRCLLGI VGSRNELRCP ECRTLVGSGV 60
EELPSNILLV RLLDGIKQRP WKPGPSGGSG TNCTNALRAQ GSTVANCSSK DLQSSQGGQQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCAAAGTCT GAAATGGATG TTACATGAAT CATTTTAAGG GATGCACACG ATTATGAACG 60
TTCCTGAAGC TTTCCTGTCA GTCAAATAGA TAAAAGATGG ATGAATCTGC CTTGTTGGAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001452--SH3_domain
IPR028502--SH3RF1
IPR018957--Znf_C3HC4_RING-type
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50002--SH3
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00018--SH3_1
PF14604--SH3_9
PF00097--zf-C3HC4

PRINTS

PR00452--SH3DOMAIN

SMART

SM00184--RING
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0043154--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0046328--P:regulation of JNK cascade

KEGG

ocu:100354589

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001528	Ailuropoda melanoleuca	89.66	0.00e+00	1315.00
IUUC-Apl-003961	Anas platyrhynchos	79.02	0.00e+00	1164.00
IUUC-Aca-004386	Anolis carolinensis	75.42	0.00e+00	1159.00
IUUC-Ame-010659	Astyanax mexicanus	73.26	7.00e-150	524.00
IUUC-Bta-012563	Bos taurus	89.32	3.00e-106	379.00
IUUC-Cja-019730	Callithrix jacchus	91.64	0.00e+00	1336.00
IUUC-Cfa-020992	Canis familiaris	89.76	0.00e+00	1360.00
IUUC-Cpo-021304	Cavia porcellus	91.96	0.00e+00	1423.00
IUUC-Csa-023925	Chlorocebus sabaeus	92.86	0.00e+00	1367.00
IUUC-Cho-024630	Choloepus hoffmanni	82.76	0.00e+00	891.00
IUUC-Cin-025274	Ciona intestinalis	46.25	5.00e-72	264.00
IUUC-Csv-026136	Ciona savignyi	42.34	8.00e-72	263.00
IUUC-Cme-027278	Cyanidioschyzon merolae	44.19	4.00e-07	50.40
IUUC-Dre-028290	Danio rerio	61.25	0.00e+00	900.00
IUUC-Dno-029083	Dasypus novemcinctus	86.96	0.00e+00	1283.00
IUUC-Dor-030388	Dipodomys ordii	95.51	0.00e+00	691.00
IUUC-Dme-032207	Drosophila melanogaster	45.90	7.00e-64	238.00
IUUC-Ete-032809	Echinops telfairi	84.29	1.00e-120	427.00
IUUC-Eca-034185	Equus caballus	91.00	0.00e+00	1091.00
IUUC-Eeu-034816	Erinaceus europaeus	78.46	0.00e+00	1135.00
IUUC-Fca-036439	Felis catus	90.10	0.00e+00	1382.00
IUUC-Fal-037074	Ficedula albicollis	78.12	0.00e+00	1141.00
IUUC-Gmo-039443	Gadus morhua	69.11	7.00e-94	338.00
IUUC-Gga-040749	Gallus gallus	81.92	0.00e+00	917.00
IUUC-Gac-041420	Gasterosteus aculeatus	73.57	4.00e-149	521.00
IUUC-Ggo-045215	Gorilla gorilla	92.52	0.00e+00	1379.00
IUUC-Hsa-046315	Homo sapiens	92.41	0.00e+00	1373.00
IUUC-Itr-048265	Ictidomys tridecemlineatus	90.27	2.00e-152	531.00
IUUC-Lch-049453	Latimeria chalumnae	69.78	0.00e+00	895.00
IUUC-Loc-052248	Lepisosteus oculatus	39.96	1.00e-77	284.00
IUUC-Laf-053651	Loxodonta africana	90.09	0.00e+00	1311.00
IUUC-Mcc-054688	Macaca mulatta	92.75	0.00e+00	1394.00
IUUC-Meu-056291	Macropus eugenii	73.53	0.00e+00	765.00
IUUC-Mga-059944	Meleagris gallopavo	77.12	0.00e+00	1142.00
IUUC-Mmr-061553	Microcebus murinus	89.84	0.00e+00	1261.00
IUUC-Mdo-062313	Monodelphis domestica	76.78	0.00e+00	1166.00
IUUC-Mmu-063516	Mus musculus	90.96	0.00e+00	1392.00
IUUC-Mpu-066064	Mustela putorius furo	89.62	0.00e+00	1334.00
IUUC-Mlu-067312	Myotis lucifugus	86.52	0.00e+00	1273.00
IUUC-Nle-069035	Nomascus leucogenys	92.08	0.00e+00	1375.00
IUUC-Opr-070690	Ochotona princeps	90.13	0.00e+00	674.00
IUUC-Ont-071484	Oreochromis niloticus	58.19	0.00e+00	853.00
IUUC-Oan-073305	Ornithorhynchus anatinus	81.49	0.00e+00	1209.00
IUUC-Ola-086675	Oryzias latipes	59.90	2.00e-174	606.00
IUUC-Oga-087933	Otolemur garnettii	81.17	0.00e+00	1021.00
IUUC-Oar-090408	Ovis aries	88.98	7.00e-108	384.00
IUUC-Ptr-090865	Pan troglodytes	92.75	0.00e+00	1378.00
IUUC-Pan-092362	Papio anubis	92.86	0.00e+00	1367.00
IUUC-Psi-093876	Pelodiscus sinensis	78.15	0.00e+00	1190.00
IUUC-Pfo-097116	Poecilia formosa	66.45	0.00e+00	723.00
IUUC-Pab-098127	Pongo abelii	92.52	0.00e+00	1376.00
IUUC-Pca-100485	Procavia capensis	96.44	0.00e+00	723.00
IUUC-Pva-102661	Pteropus vampyrus	87.17	0.00e+00	1271.00
IUUC-Rno-105728	Rattus norvegicus	88.74	0.00e+00	1340.00
IUUC-Sha-106515	Sarcophilus harrisii	85.36	0.00e+00	862.00
IUUC-Sar-113161	Sorex araneus	94.94	0.00e+00	664.00
IUUC-Ssc-115314	Sus scrofa	92.60	0.00e+00	683.00
IUUC-Tgu-117012	Taeniopygia guttata	78.46	0.00e+00	1149.00
IUUC-Tru-118467	Takifugu rubripes	63.21	6.00e-158	551.00
IUUC-Tsy-119566	Tarsius syrichta	83.60	9.00e-177	613.00
IUUC-Tni-120830	Tetraodon nigroviridis	58.45	3.00e-167	582.00
IUUC-Tbe-128070	Tupaia belangeri	96.95	0.00e+00	731.00
IUUC-Ttr-128161	Tursiops truncatus	94.90	5.00e-143	501.00
IUUC-Xtr-132628	Xenopus tropicalis	77.05	0.00e+00	887.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence