iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111285

Ensembl Protein ID

Solyc07g065630.2.1

UniProt Accession

K4CHP1; K4CHP1_SOLLC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc07g065630.2	Solyc07g065630.2.1	Solyc07g065630.2.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.60e-122	408.3	3418	3756
UBD/Alpha-Helix/UBA	7.10e-09	36.3	1296	1335

Active Site

Position(s)	Description	Evidence
3724	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 3    sdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlp 91
           +dlk rl+v+f+gEeg+d+gG+tre+++lls+ ++++ + lf ++ ++++t+qpnp+s ++ +ehl++F+f+Gr+++kal+dg+lld++
   Q: 3418 QDLKGRLNVHFQGEEGIDAGGLTREWYQLLSRVIFDKGALLF-TTVGNNATFQPNPNSVYQ-TEHLSYFKFVGRVVAKALFDGQLLDVH 3504
           79************************************9999.566688999******986.5************************** PP
   S: 92   lsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.....lgetkeeeLkpgGenipVtneNkeeYvk 175
           +++sfyk++lg+k++++d+e+vdp++yk+lk+++en+ sdi +l++ +   ++ee+       e++++eLkpgG+ni+Vt+e k+eYv+
   Q: 3505 FTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWMLENDVSDIPDLTFSMD--ADEEKlilyeKTEVTDYELKPGGRNIRVTEETKHEYVD 3591
           ************************************6666666533333..444446784445566778******************** PP
   S: 176  lvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerkaf 264
           lv++++l++ i+ q++af eGf+e++p el+s+F+ +elelli+G +eid+edlk++t+y+g yt  s aiqwFwev+++fs+e+ ++f
   Q: 3592 LVADHILTNAIRPQINAFLEGFSELVPRELISIFNDKELELLISGLPEIDMEDLKANTEYTG-YTTASTAIQWFWEVVKGFSKEDMARF 3679
           ************************************************************66.************************** PP
   S: 265  LqFvTgssrlPlgGfaelk....prlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           LqFvTg+s++Pl+Gf++l+    p++f+i+k +++++rlPs++TCfn+L+LPeY+ske+l+e+Ll+Ai+e+ +gF++
   Q: 3680 LQFVTGTSKVPLEGFKALQgisgPQRFQIHKaYGAPERLPSAHTCFNQLDLPEYTSKEQLQERLLLAIHEAsEGFGF 3756
           *******************************99999***********************************9***85 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLldg 41
           de  +  +veMGF+r +a +aLr+   n++e+A+e+L+++
   Q: 1296 DETTISTIVEMGFSRGRAEEALRRVeTNSVEMAMEWLFSH 1335
           78999*******************66************97 PP

Organism

Solanum lycopersicum

Protein Sequence
(Fasta)

MKLKRRRAVE VPPKIRSFIS SITATPLENI EEPLKSFVWE FDKGDFYHWV DLFNHFDTFF 60
EKYIKYRKDL QFDDHFLESD PQFPREAVLQ VLRVIRIILE NCTNKHFYSS YEHHLSALLA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAAGTTAA AGCGAAGGAG GGCTGTAGAA GTGGTAAGTG ATATATGTAT ATGTTTTTGA 60
TTTTTTGATC ATACGTGAAT TGGTTCGAAG CGTGATTGTT CGGTGGTTTT TTTAGGTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001684	Ailuropoda melanoleuca	51.67	1.00e-127	452.00
IUUC-Atr-003044	Amborella trichopoda	58.77	0.00e+00	3735.00
IUUC-Aca-005263	Anolis carolinensis	51.67	7.00e-128	453.00
IUUC-Aly-006083	Arabidopsis lyrata	60.66	0.00e+00	2622.00
IUUC-Ath-007472	Arabidopsis thaliana	61.94	0.00e+00	4137.00
IUUC-Ame-011067	Astyanax mexicanus	51.66	8.00e-127	449.00
IUUC-Bta-012813	Bos taurus	51.67	1.00e-127	452.00
IUUC-Bra-016637	Brassica rapa	58.32	0.00e+00	3793.00
IUUC-Cel-018179	Caenorhabditis elegans	44.38	4.00e-121	430.00
IUUC-Cja-018741	Callithrix jacchus	51.78	4.00e-127	450.00
IUUC-Cfa-020083	Canis familiaris	51.67	1.00e-127	452.00
IUUC-Csa-023853	Chlorocebus sabaeus	51.67	9.00e-128	452.00
IUUC-Cho-024718	Choloepus hoffmanni	54.45	2.00e-117	418.00
IUUC-Dre-028525	Danio rerio	50.36	5.00e-113	404.00
IUUC-Dno-029680	Dasypus novemcinctus	51.67	7.00e-128	452.00
IUUC-Dor-030902	Dipodomys ordii	46.33	2.00e-108	388.00
IUUC-Dme-032122	Drosophila melanogaster	51.05	4.00e-123	437.00
IUUC-Eca-033915	Equus caballus	51.12	1.00e-125	445.00
IUUC-Eeu-034963	Erinaceus europaeus	51.33	1.00e-125	446.00
IUUC-Fca-035824	Felis catus	51.67	1.00e-127	452.00
IUUC-Gmo-039073	Gadus morhua	51.89	2.00e-128	454.00
IUUC-Gac-042430	Gasterosteus aculeatus	51.89	3.00e-128	454.00
IUUC-Gma-044247	Glycine max	67.06	0.00e+00	4371.00
IUUC-Hsa-046879	Homo sapiens	51.67	2.00e-127	452.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	51.67	9.00e-128	451.00
IUUC-Lch-050252	Latimeria chalumnae	52.00	3.00e-127	451.00
IUUC-Lpe-050915	Leersia perrieri	56.96	0.00e+00	3499.00
IUUC-Loc-052472	Lepisosteus oculatus	53.40	5.00e-128	453.00
IUUC-Laf-054154	Loxodonta africana	51.67	8.00e-128	452.00
IUUC-Mcc-055085	Macaca mulatta	51.67	8.00e-128	452.00
IUUC-Meu-056436	Macropus eugenii	40.36	6.00e-76	278.00
IUUC-Mtr-058088	Medicago truncatula	65.00	0.00e+00	2607.00
IUUC-Mmr-060820	Microcebus murinus	51.67	8.00e-128	452.00
IUUC-Mdo-062930	Monodelphis domestica	51.67	5.00e-128	453.00
IUUC-Mmu-063601	Mus musculus	51.67	1.00e-127	452.00
IUUC-Mac-065557	Musa acuminata	53.17	0.00e+00	1562.00
IUUC-Mpu-066653	Mustela putorius furo	51.67	1.00e-127	452.00
IUUC-Mlu-067418	Myotis lucifugus	51.67	8.00e-128	452.00
IUUC-Nle-069418	Nomascus leucogenys	51.67	1.00e-127	452.00
IUUC-Ont-071300	Oreochromis niloticus	51.89	3.00e-128	454.00
IUUC-Oan-073046	Ornithorhynchus anatinus	51.44	2.00e-126	448.00
IUUC-Ocu-074178	Oryctolagus cuniculus	51.67	6.00e-128	453.00
IUUC-Oba-075252	Oryza barthii	55.13	0.00e+00	2219.00
IUUC-Obr-076762	Oryza brachyantha	56.45	0.00e+00	3466.00
IUUC-Ogl-077590	Oryza glaberrima	58.88	0.00e+00	1265.00
IUUC-Ogu-077981	Oryza glumaepatula	55.04	0.00e+00	2164.00
IUUC-Oin-079663	Oryza indica	52.16	0.00e+00	1940.00
IUUC-Olo-080326	Oryza longistaminata	55.01	0.00e+00	2197.00
IUUC-Oni-082342	Oryza nivara	55.07	0.00e+00	2245.00
IUUC-Opu-083428	Oryza punctata	56.85	0.00e+00	3465.00
IUUC-Oru-084559	Oryza rufipogon	55.17	0.00e+00	2213.00
IUUC-Osa-086200	Oryza sativa	66.84	0.00e+00	1268.00
IUUC-Olu-087813	Ostreococcus lucimarinus	52.80	1.00e-126	445.00
IUUC-Oga-088903	Otolemur garnettii	51.67	1.00e-127	452.00
IUUC-Oar-090210	Ovis aries	51.67	7.00e-128	453.00
IUUC-Ppa-095657	Physcomitrella patens	49.49	0.00e+00	1762.00
IUUC-Pfo-096232	Poecilia formosa	51.89	2.00e-128	455.00
IUUC-Pab-098583	Pongo abelii	51.67	1.00e-127	452.00
IUUC-Pop-099520	Populus trichocarpa	67.01	0.00e+00	4435.00
IUUC-Pca-100596	Procavia capensis	38.95	1.00e-88	320.00
IUUC-Ppe-102109	Prunus persica	70.10	0.00e+00	4703.00
IUUC-Pva-102116	Pteropus vampyrus	47.77	3.00e-113	404.00
IUUC-Sha-106961	Sarcophilus harrisii	51.67	6.00e-128	453.00
IUUC-Spo-108024	Schizosaccharomyces pombe	32.20	5.00e-141	496.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	45.48	1.00e-95	343.00
IUUC-Smo-109640	Selaginella moellendorffii	42.98	0.00e+00	1606.00
IUUC-Sit-110149	Setaria italica	53.27	0.00e+00	2042.00
IUUC-Stu-112501	Solanum tuberosum	99.20	0.00e+00	686.00
IUUC-Sar-113291	Sorex araneus	52.62	2.00e-122	435.00
IUUC-Sbi-113794	Sorghum bicolor	47.30	0.00e+00	1789.00
IUUC-Ssc-115754	Sus scrofa	51.67	1.00e-127	452.00
IUUC-Tru-118570	Takifugu rubripes	51.89	1.00e-128	455.00
IUUC-Tni-120836	Tetraodon nigroviridis	51.00	2.00e-124	441.00
IUUC-Tca-121646	Theobroma cacao	69.76	0.00e+00	4617.00
IUUC-Tbe-127793	Tupaia belangeri	37.45	7.00e-85	308.00
IUUC-Ttr-129253	Tursiops truncatus	51.67	1.00e-127	452.00
IUUC-Vpa-130708	Vicugna pacos	51.67	2.00e-127	451.00
IUUC-Vvi-131559	Vitis vinifera	74.15	0.00e+00	2035.00
IUUC-Xtr-132123	Xenopus tropicalis	49.23	2.00e-115	411.00
IUUC-Xma-133869	Xiphophorus maculatus	51.89	1.00e-128	455.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence