iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000017342.3	ENSMMUT00000053695.1	ENSMMUP00000054548.1
ENSMMUG00000017342.3	ENSMMUT00000073300.1	ENSMMUP00000041971.1
ENSMMUG00000017342.3	ENSMMUT00000041548.2	ENSMMUP00000034574.2
ENSMMUG00000017342.3	ENSMMUT00000024384.3	ENSMMUP00000022822.3
ENSMMUG00000017342.3	ENSMMUT00000069122.1	ENSMMUP00000047792.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	5.70e-21	75.8	50	117
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	2.40e-11	42.7	150	180

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dv++v ++ e++ah++vLaa+S++F+a+f++e++es+  ++v ik+v+   +r l++++Yt +++ +e
   Q: 50   CDVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESR-AKRVRIKEVDGWTLRMLIDYVYTAEIQVTE 117
           8*************************************.*************************99765 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 2    eNclgilrfAdlydcpdLkdaaldfilkhFk 32
            Nclgi++fAd++ c+dL  +a++++++hF+
   Q: 150  VNCLGIRAFADMHACTDLLNKANTYAEQHFT 180
           6*****************************7 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MYRCTKQGHQ KPLDSKDDNT EKHCPVTVNP WHMKKAFKVM NELRSQNLLC DVTIVAEDME 60
ISAHRVVLAA CSPYFHAMFT GEMSESRAKR VRIKEVDGWT LRMLIDYVYT AEIQVTEENV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCGCCCGCCG GTCCCGTCGC CGCCGCCCAG CACTCGGGCG AGCGCGGGAG CCGCGCAGTA 60
GACGGAGCGC GCCTGGCCGA GCCGGCCATG GCCGCGGGGG CCGCCGCCGC AGGTGGTGGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0003779--F:actin binding
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002378	Ailuropoda melanoleuca	98.11	0.00e+00	1149.00
IUUC-Apl-003260	Anas platyrhynchos	92.28	0.00e+00	1089.00
IUUC-Aca-005143	Anolis carolinensis	87.99	0.00e+00	1079.00
IUUC-Cel-018136	Caenorhabditis elegans	41.42	7.00e-124	437.00
IUUC-Cja-018942	Callithrix jacchus	98.12	0.00e+00	1155.00
IUUC-Cfa-020886	Canis familiaris	98.46	0.00e+00	1162.00
IUUC-Cpo-022543	Cavia porcellus	98.63	0.00e+00	1156.00
IUUC-Csa-023088	Chlorocebus sabaeus	98.97	0.00e+00	1157.00
IUUC-Csv-026032	Ciona savignyi	60.30	0.00e+00	689.00
IUUC-Dre-028082	Danio rerio	80.96	0.00e+00	964.00
IUUC-Dno-029873	Dasypus novemcinctus	96.10	0.00e+00	1137.00
IUUC-Dor-030460	Dipodomys ordii	78.04	0.00e+00	841.00
IUUC-Dse-031229	Dothistroma septosporum	37.14	5.00e-08	51.20
IUUC-Dme-032172	Drosophila melanogaster	61.47	0.00e+00	663.00
IUUC-Eca-033798	Equus caballus	97.77	0.00e+00	1150.00
IUUC-Eeu-034824	Erinaceus europaeus	90.04	0.00e+00	954.00
IUUC-Fca-036455	Felis catus	98.46	0.00e+00	1162.00
IUUC-Fal-037293	Ficedula albicollis	91.70	0.00e+00	1028.00
IUUC-Gmo-038811	Gadus morhua	77.93	0.00e+00	862.00
IUUC-Gga-040805	Gallus gallus	91.78	0.00e+00	1087.00
IUUC-Gac-041979	Gasterosteus aculeatus	80.56	0.00e+00	868.00
IUUC-Ggo-044620	Gorilla gorilla	93.49	0.00e+00	1094.00
IUUC-Hsa-046265	Homo sapiens	98.63	0.00e+00	1155.00
IUUC-Lch-049939	Latimeria chalumnae	82.76	0.00e+00	964.00
IUUC-Loc-052780	Lepisosteus oculatus	86.11	0.00e+00	1019.00
IUUC-Laf-053800	Loxodonta africana	97.61	0.00e+00	1152.00
IUUC-Meu-056011	Macropus eugenii	95.19	0.00e+00	1038.00
IUUC-Mmr-061067	Microcebus murinus	98.61	0.00e+00	1144.00
IUUC-Mdo-062977	Monodelphis domestica	94.68	0.00e+00	1119.00
IUUC-Mmu-064035	Mus musculus	98.43	0.00e+00	1142.00
IUUC-Mpu-066726	Mustela putorius furo	98.63	0.00e+00	1163.00
IUUC-Mlu-067020	Myotis lucifugus	97.95	0.00e+00	1151.00
IUUC-Nle-069456	Nomascus leucogenys	98.12	0.00e+00	1158.00
IUUC-Opr-071130	Ochotona princeps	87.99	0.00e+00	1006.00
IUUC-Ont-072219	Oreochromis niloticus	81.16	0.00e+00	919.00
IUUC-Oan-073699	Ornithorhynchus anatinus	93.29	0.00e+00	946.00
IUUC-Ocu-074045	Oryctolagus cuniculus	97.94	0.00e+00	1148.00
IUUC-Oga-088494	Otolemur garnettii	97.95	0.00e+00	1156.00
IUUC-Oar-089645	Ovis aries	97.77	0.00e+00	1146.00
IUUC-Ptr-091063	Pan troglodytes	98.63	0.00e+00	1155.00
IUUC-Pan-092273	Papio anubis	100.00	0.00e+00	959.00
IUUC-Psi-093946	Pelodiscus sinensis	90.82	0.00e+00	1098.00
IUUC-Pma-094177	Petromyzon marinus	74.51	0.00e+00	796.00
IUUC-Pfo-096817	Poecilia formosa	80.14	0.00e+00	932.00
IUUC-Pab-097768	Pongo abelii	98.46	0.00e+00	1153.00
IUUC-Pca-100607	Procavia capensis	82.35	0.00e+00	830.00
IUUC-Pva-102218	Pteropus vampyrus	92.28	0.00e+00	1066.00
IUUC-Rno-105250	Rattus norvegicus	97.60	0.00e+00	1144.00
IUUC-Sar-113249	Sorex araneus	98.43	0.00e+00	1141.00
IUUC-Ssc-115423	Sus scrofa	97.95	0.00e+00	1153.00
IUUC-Tgu-117050	Taeniopygia guttata	90.58	0.00e+00	1072.00
IUUC-Tru-118239	Takifugu rubripes	81.12	0.00e+00	960.00
IUUC-Tsy-119377	Tarsius syrichta	83.88	0.00e+00	988.00
IUUC-Tni-120122	Tetraodon nigroviridis	81.27	0.00e+00	877.00
IUUC-Ttr-128574	Tursiops truncatus	99.41	0.00e+00	700.00
IUUC-Vpa-130707	Vicugna pacos	93.55	0.00e+00	860.00
IUUC-Xtr-132035	Xenopus tropicalis	85.84	0.00e+00	1040.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence