iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMUSG00000040811.15	ENSMUST00000117338.7	ENSMUSP00000112491.1
ENSMUSG00000040811.15	ENSMUST00000120595.7	ENSMUSP00000112447.2
ENSMUSG00000040811.15	ENSMUST00000148246.7	ENSMUSP00000115466.1
ENSMUSG00000040811.15	ENSMUST00000048502.9	ENSMUSP00000037654.8

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress	GXD
DNA & RNA Element
AREsite	circBase	microRNA	TRANSFAC
RAID2
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	9.60e-19	67.8	696	732
UBD/Beta-Prp	1.60e-40	140.3	638	838

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gH++ +t l++ +d t +v+ s+D  i  WD+ t+++
   Q: 696  GHSSFITHLDWaQDsTCFVTNSGDYEILYWDPVTCKQ 732
           8***********888****************999876 PP

UBD/Beta-Prp

   S: 80   dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee...tlsghdgvvncvvvhpdgnllvsGslDrtvrlWd 165
           d +t + v + +  ++++  +sfsp+g +l++Gshd+ + v+ +++g    +     sgh+++++++ + +d+ ++v+ s D  +  Wd
   Q: 638  DTETHDLVAIHTDGNEQISVVSFSPDGAYLAVGSHDNLVYVYTVDQGGRKVSrlgKCSGHSSFITHLDWAQDSTCFVTNSGDYEILYWD 726
           889999999999**********************************99998889999******************************** PP
   S: 166  l.................ktgkllrtl.......tgghtdsvyslsfdsngkelvsgsldgtvklwdlq...tgecvrtlnghtdnvks 227
                             +t++++  +       +g++  +++ ++ +++gk lvs+++ g+v l+++         +++ gh++ v+ 
   Q: 727  PvtckqitsadtvrnvewATATCVLGFgvfgiwpEGADGTDINAVARSHDGKLLVSADDFGKVHLFSYPccqPRALSHKYGGHSSHVTN 815
           **********************************9********************************98776666799*********** PP
   S: 228  vrfs.pnderlvsgssDgsiriW 249
           v+f+ +++  l +g++D s+  W
   Q: 816  VAFLwDDSMALTTGGKDTSVLQW 838
           ***978888899999*****999 PP

Organism

Mus musculus

Protein Sequence
(Fasta)

MATGGRAWGG DRARAGAAGA GGGCGGAMAE RGPAFCGLYD TSSLLQYCND DNLSGTSGME 60
VDDRVSALEQ RLQLQEDELA VLKAALADAL RRLRACEEQG AALRARSTPK GRAPPRLGTT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGACAGTACC TAGGGGGACC CCGACGCAGC CAATCCTGAC CTGAAGACTG TTGCGGGGGT 60
TGGGGGAACG GACAGAGCAG TCTCTCGACA CCCTTACAGG GCATCCTAGG GGATGACCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR005108--HELP
IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF03451--HELP
PF00400--WD40

SMART

SM00320--WD40

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002155	Ailuropoda melanoleuca	95.11	0.00e+00	1466.00
IUUC-Aca-005316	Anolis carolinensis	74.65	0.00e+00	1158.00
IUUC-Ame-011647	Astyanax mexicanus	66.08	0.00e+00	1040.00
IUUC-Bta-013267	Bos taurus	95.21	0.00e+00	1508.00
IUUC-Cja-019146	Callithrix jacchus	89.44	0.00e+00	1211.00
IUUC-Cfa-020267	Canis familiaris	96.19	0.00e+00	1523.00
IUUC-Cin-025784	Ciona intestinalis	54.95	0.00e+00	747.00
IUUC-Csv-026305	Ciona savignyi	48.25	0.00e+00	753.00
IUUC-Dre-028734	Danio rerio	66.63	0.00e+00	1084.00
IUUC-Dno-028961	Dasypus novemcinctus	93.33	0.00e+00	1437.00
IUUC-Eca-033785	Equus caballus	94.70	0.00e+00	1496.00
IUUC-Eeu-035302	Erinaceus europaeus	93.46	0.00e+00	715.00
IUUC-Fca-036170	Felis catus	91.59	0.00e+00	1420.00
IUUC-Gac-042643	Gasterosteus aculeatus	63.87	0.00e+00	1004.00
IUUC-Ggo-044669	Gorilla gorilla	90.93	0.00e+00	1397.00
IUUC-Hsa-046141	Homo sapiens	95.67	0.00e+00	1514.00
IUUC-Itr-048788	Ictidomys tridecemlineatus	94.36	0.00e+00	1489.00
IUUC-Loc-052518	Lepisosteus oculatus	67.93	0.00e+00	1065.00
IUUC-Laf-054137	Loxodonta africana	89.64	0.00e+00	1170.00
IUUC-Mcc-055780	Macaca mulatta	94.38	0.00e+00	1184.00
IUUC-Meu-056664	Macropus eugenii	83.33	0.00e+00	1121.00
IUUC-Mmr-060853	Microcebus murinus	94.55	0.00e+00	1502.00
IUUC-Mdo-062224	Monodelphis domestica	85.11	0.00e+00	1182.00
IUUC-Mpu-066043	Mustela putorius furo	96.17	0.00e+00	1516.00
IUUC-Mlu-067125	Myotis lucifugus	74.21	0.00e+00	1051.00
IUUC-Nle-069618	Nomascus leucogenys	87.28	0.00e+00	1297.00
IUUC-Opr-070228	Ochotona princeps	87.09	0.00e+00	1141.00
IUUC-Ont-071258	Oreochromis niloticus	64.38	0.00e+00	1028.00
IUUC-Ocu-074087	Oryctolagus cuniculus	82.08	0.00e+00	856.00
IUUC-Oga-088048	Otolemur garnettii	92.01	0.00e+00	1444.00
IUUC-Oar-089907	Ovis aries	94.42	0.00e+00	1234.00
IUUC-Pan-092082	Papio anubis	95.45	0.00e+00	1509.00
IUUC-Pfo-096717	Poecilia formosa	62.44	0.00e+00	1020.00
IUUC-Pab-097619	Pongo abelii	94.74	0.00e+00	1274.00
IUUC-Pca-101070	Procavia capensis	83.83	0.00e+00	1085.00
IUUC-Pva-102957	Pteropus vampyrus	89.74	0.00e+00	1188.00
IUUC-Rno-105074	Rattus norvegicus	98.29	0.00e+00	1284.00
IUUC-Sha-106692	Sarcophilus harrisii	82.60	0.00e+00	1233.00
IUUC-Tru-117809	Takifugu rubripes	62.42	0.00e+00	1067.00
IUUC-Tni-120815	Tetraodon nigroviridis	63.45	0.00e+00	1077.00
IUUC-Ttr-128263	Tursiops truncatus	89.66	0.00e+00	1201.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence